Vitamin C and NAC

Someone sent me this article about Vitamin C and NAC. Can our science folks take a look and see if this information is suspect? http://unisci.com/stories/20013/0927015.htm< Raven
I also found this article on NACi and endotoxini<
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9436612&dopt=Abstract
 
Raven 

Feeling 98% well-going for 100. Very low test for Cpni. CAPi since 8-05 for Cpn/Mycoplasma P.,Lyme, Bartonella, Mold exposure,NACi,BHRT, MethyB12 FIRi Sauna. 1-18-11 begin new treatment plan with naturopath

Note that this first study is on an N=14, a very small grouping to be making any speculative conclusions from. This is only of interest if it should be a repeated finding. As it stands, there is such an overwhelming number of studies showing antioxidant">i and other useful effects of these supplementsi, the following study you cite is an example especially in endotoxini diseasesi such as Cpni, that I would hold this aside until further findings.

On Wheldon/Stratton protocol for Cpn in CFSi/FMSi since December 2004.

 

CAPi for Cpni 11/04. Dxi: 25+yrs CFSi & FMSi. Currently: 250 aithromycin mwf, doxycycline 100mg BIDi, restarted Tinii pulses; Vit D2000 units, T4 & T3, 6mg Iodoral

The information in the first article is sound enough as far as it goes, yet they do not differentiate between what was obviously a severe crush of the bicep muscle and other things inflammatory.  What they did to these people will have let large amounts of free iron loose in haemo and myoglobins.  It isn't the same as having a CPni infection.  Besides which they say that the treatment was damaging, but they do not say how, just that there was release of free iron.  I have been taking about three times the amount of vitamin C used in this experiment for at least a couple of years, and more than twice the mount of NACi for about six months at least, yet I show no signs of damage.  In fact my hair has grown by more than half an inch a month this year and my fingernails seem to grow enormously just overnight.  That doesn't sound like I am being harmed.  I think the second paper is far more relevant to people with our infection.........Sarah
Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.
Looking at the abstract of the first study it seems well-mounted and well-reasoned, and the study gave results other than those which were hypothesised, which is always more interesting. If I read the abstract rightly (and it's always risky to read an abstract alone) the authors studied bruised muscle, where there would have been a lot of degenerating myoglobin from dying muscle and haemoglobin from extravasated blood (think of how bruises change colour) and thus a lot of free extracellular iron. This would seem to be a very different case from that of cpni infection where free iron is not - as far as I know - a feature. In fact iron-depletion seems to be a well-established macrophage strategy against cpn infection. There's a vast difference between the situation within cells and in the extracellular millieu around damaged cells. But these are only tentative thoughts.
D W - [Myalgia and hypertension">i (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazolei. No medication now. Morning BP typically 110/75]

Comment viewing options

Select your preferred way to display the comments and click "Save settings" to activate your changes.