Cpn-related research: Member-posted

Interesting Article on Study: Vit D3, Parathyroid Levels and Risk of Falls

Here's an interesting article on a recent study.  I've read quite a bit about the potential link between low levels of Vit D3 and the risk of falls, particularly in the elderly, but I've never really read an explanation why this might occur.    

The last paragraph in the clinical context section of this article attempts to explain the link as follows:

Interesting study on investigational drug rifalazil for treatment of C. pneumoniae

J Antibiot (Tokyo). 2008 Aug;61(8):489-95. Links

Rifalazil Retains Activity Against Rifampin-resistant Mutants of Chlamydia pneumoniae.

Vitamin D Pathways - Importance of IL-15

Here's another interesting area to keep an eye on, namely the apparent importance of IL-15 for bioconversion of 5-hydroxyvitamin D3 (25D3) into bioactive 1,25D3 and the downstream induction of cathelicidins:

Chronic Chlamydia pneumoniae infection and bronchial asthma: Is there a link?

: Indian J Med Microbiol. 2008 Oct-Dec;26(4):338-41.

Chronic Chlamydia pneumoniae infection and bronchial asthmai: Is there a link?

Agarwal A, »

Vitamin D and the immune system: role in protection against bacterial infection.

Curr Opin Nephrol Hypertens. 2008 Jul;17(4):348-52.

Interesting Study on Importance of Vitamin D3 for Proper Thyroid Function

 

Since so many on the site are dealing with thyroid issues, I thought I'd pass this along...

First, here's a little news blurb on the study:

Modern Medicine: Vitamin D Directly Affects Thyroid Function in Mice

 

Below is the full study article.  While the article focuses on Graves' hyperthyroidism, the discussion and conclusion sections list some interesting findings of recent research on Vitamin D3's importance for proper thyroid function in general.   It's well worth a read:

Blastocystis, and IBS

This could be another reason why the CAPi helps IBSi: the flagyli pulses are antiprotozoan.

[To read or download the full text of this 50-page open access article at no charge, click here.]

Blastocystis is a prevalent enteric protozoan that infects a variety of vertebrates. Infection with Blastocystis in humans has been associated with abdominal pain, diarrhea, constipation, fatigue, skin rash, and other symptoms.

Are Influenza Epidemics a Result of Low Sunlight and Vitamin D?

Gotta love this one.

On the Epidemiology of Influenza - Source: Virology Journal, Feb 2008

by John J Cannell, et al.
October 12, 2008

[Note: the full text of this open-access article, outlining evidence that sun/vitamin Di status could have "profound implications for the prevention of influenza" is available free at http://www.virologyj.com/content/5/1/29 ]

Prof. Solbach

Hi everybody,

Gieffers, Rupp and Solbach published about Cpni, especially about Cpn in macrophages and its persistencei even in the presence of antibioticsi.

Prof. Dr. Solbach is head of the Institute for medical microbiology and hygiene at Lübeck, Germany.

I just talked to him on the phone. Prof. Solbach is very interested in the topic and our community in the internet. I invited him to post here and give directly into our discussion. He kindly accepted.

So stay tuned ...

Greez

Andreas

Molecular detection of Parachlamydia-like organisms in cerebrospinal fluid of patients with multiple sclerosis.

Mult Scler. 2008 May;14(4):564-6

Molecular detection of Parachlamydia-like organisms in cerebrospinal fluid of patients with multiple sclerosis.

Cpn DNA and mRNA in PMBC's and CSF of patients with multiple sclerosis.

Neurosci Res. 2008 Sep;62(1):58-61.

Chlamydophila pneumoniae cultured from the late-onset Alzheimer brain

Int J Med Microbiol. 2008 Sep 29. [Epub ahead of print]Click here to read

Initial characterization of Chlamydophila (Chlamydia) pneumoniae cultured from the late-onset Alzheimer brain.

Dreses-Werringloer U, Bhuiyan M, Zhao Y, Gérard HC, Whittum-Hudson JA, Hudson AP. Department of Immunology and Microbiology, Wayne State University School of Medicine, Gordon H. Scott Hall, 540 East Canfield Avenue, Detroit, MI 48201, USA.

Is leucine working?

Hello,

I remember some of you saying you started taking leucine immediately after learning about it from Andreas.

Have you felt any changes attributable to the supplement?

How much are you taking?

When I get my 500 g supply I will probably dissolve several grams in a liter of water and take it throughout the day, to somewhat replicate the experiment described in the thesis. I haven't figured out the quantity yet.

Before getting your updates I remain somewhat skeptical since no increase in the leucine concentration was found in the cells of the treated mice.

Let's see first how you're doing.

New TB Vaccine wakes persisters

Came across this today, and thought it was very interesting (for obvious reasons).

http://news.bbc.co.uk/1/hi/wales/mid/7656676.stm

Ground-breaking research by scientists in Wales and Russia is being used to develop a new vaccine for tuberculosis. Aberystwyth University and the Russian Academy of Sciences have been working in partnership for a decade.

Scientists discovered a new protein in humans in the late 1990s, which is now being developed to control bacteria which cause tuberculosis (TB).

Work started on the vaccine in the late 1990s, when researchers discovered a new family of proteins able to "resuscitate bacteria" found harmlessly in and around the human body.

More and more on Vitamin D

Following are some new Vitamin Di abstracts by Holick. With 1,25-dihydroxyvitamin D involved in regulating more than 200 genesi, you would think it might not be such a good idea to formulate treatment around Vitamin D starvation...
Jim