This may sound somewhat superficial but effects me greatly. The only reason it really effects me is, I have always had problems with social phobia but was able to deal. When people would look at me, I would think the worse, can't really explain it. I think it all started when I had a bad bout of acne in my college yrs. It effected me greatly.

Then I was struck with this disease and it totally ruined my esteem.

I'm get anxious when I keep hearing 'are you tired, you look tired' which means you look like shit..

I lost a lot of facial muscle and fat and the cpni ruined my complexion to the point of wanting to hide indoors. I can't believe how self-conscience this is making me.

Addendum to my blog.  It's day 21 post pulse. I am depressed and sick and tired of being sick and tired.  I guess it's finally hit.  I only took 1- 250 mg of Tindamax for 2 days.  Nothing really happened until now.  I was experiencing pelvic/gut pain but kept writing it off to the pulse.  so I then went the route of gyn and  urologist which has led me to:

1) I have a bladder infection  -- was prescribed Nitrofurantoin 100 mg BID. 

2) Per gyn - I  have BV and gyn wants me to use Clindesse -- I have not administered it yet as I am concerned I'll be on antibiotic overload and could possibly cause another pulse or yeasst.  I have no idea how it would interact with CPNi.

Hi there,

Has anyone ever used enzymes and in particular Serrazimes to help clean up excess fibrin and inflammationi and possibly endotoxini load?

Thanks!! 

Before i started the Capi I was treated against chronic enterovirus (Dr.John Chia Protocoll) with Interferon Alpha, Interferon gammai and Ribavirin.

Since Interfereron gamma activates also the macrophages and the cleaning up system in your body , I am thinking of taking some of my interferon gamma , I still have som left in my fridge.

Anyone experienced Interferon gamma ?

Thanks and Greeings from Hamburg/Germany

Here on the CAPi do we have anything in our arsenal to mediate or help lessen the the Cytokinei/Chemokine storm?

I always have Benicar on hand (as does Jim K I have read) if things get out of control.  I just wonder if Stratton or Wheldon have really put any necessity behind this.

Some times when I herx the Cytokine storm can become overwhelming having me reach for a benzo which is somewhat known to help with cytokinesi (per Cheney)

Any other suggestions or research done here on this?

Bacterial Endotoxini in Human disease

http://www.xoma.com/pdfs/kpmgendo.pdf 

Link in Handbook is disfunctional currently.

Is anyone else with Celiac Disease or knowledge of Celiac Disease a user on this website?

Over the past 3 days my walking has gotten progressively worse.  My right knee is so swollen and painful I can't bend or move it. When I walk I try to "make up" for my peg leg with my good leg... now my left leg is starting to give me pain.  I had a dr. appt and he seems to think it's bursitis.  My FM symptoms are also worsening... again this all started with the addition of Azith.  Katman, I know you said you had extreme joint pain/problems..... anyone else?

Actually, 6 months and 2 days... the 27th of September marked six months of my being on CAPi.  As Ruth mentioned in a previous post about herself, I am no longer a newbie!  I am now reading posts of those coming on board, reflecting on my past experiences!  It's a strange feeling indeed -- firstly, to realize how many of us there are "out there".  It is wonderful that people are finding this website -- the word is getting out.

As I read of those coming on board it's a curiosity to gauge the different levels of tolerance the individuals have.  Some are able to ramp up on the meds quite quickly and others, like me, struggle to build up to each level.  I guess this is also indicative of our unique immunei systems and the CPNi load each of us carries.

 Dr. David Wheldoni's succinct summary of the different reactions to Cpni and its treatment helps in sorting out the different responses and what to do about them. I've moved this from his comment in another members blog post to a page of it's own here in the Cpn Treatment Handbook.

Jim K (Editor in Chief) 

Five Ways of Feeling Lousy

I am inclined to think that there are five major mechanisms behind those unpleasant side effects of chronic large-load infection with C pneumoniae which worsen in the short-term with antichlamydial treatment.

a) Lipid peroxidation may likely get worse in the short-term as bacterial products are released both by breaking down EBs and by apoptosisi of infected cells. Antioxidantsii and B vitaminsi (including B12) may help with this. I find melatoninii at night helpful.

Hi everyone,

Part of the bloodwork that I had indicated that I have several deficiencies in my immunoglobulins.  Specifically, I have a very low IgM, IgG3, and IgG4. (My total IgG looks normal, but those two subclasses are below normal levels.)

Have any of you had any tests with those sorts of results or any other Ig deficiency?  Have the tests improved because of/during your time on these antibiotics?

Do the IV antibodies have any chance at all at getting at the cpni inside cells?  Hmm... also, if it does get to them, do I run some sort of risk by having them go nuts on the cpn?

If you have had experience in general with IVIG, I would like to know how you responded.

I believe my doc is willing to treat me with intravenous immunoglobulins to bring the IgG up.  However, if the IgG is low because of CPN or something like it, I'll definitely need to keep on the abxi.  However, I'm scratching my head as to how to tell the difference between the IVIG fixing me and the abxi fixing me. (I have read stories of people who only needed one or two infusions and they were actually completely "cured"... it seemed that their body just needed the temporary boost to get their own systems going...)