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Immune system

AHCC (Active Hexose Correlated Compounds)

My mom wants me to take it... anyone?

ATP and low CD4 counts

first off, thanx again to everyones comments, this site can be soooooooooo informative! 

Adrenal Fatigue

Has anyone here been diagnosed with "adrenal fatigue" or "adrenal burnout"? Been treated for it? Recovered from it?

The new doc I'm seeing says it's critical to treat any adrenal fatigue that may be present or CAPi won't work very well or will take longer than necessary. What do you know of adrenal fatigue and its relation to chronic infection and recovery?

Darn Coldsore......

a miniscule marker in my treatment, but I have NEVER in my life had a coldsore..... and I now have one that appeared this morning out of nowhere.  Guess the antibiotic's are finding the infectionsi in my body!  Last week,  I was getting small, inflammed red bumps (looked like a pimple coming on)  randomly around my mouth... just a few.

Past two weeks have been EXTREMELY difficult -- my fatigue and weakness have me down almost all day.... I am having "wiggy" porphyric episodes again (waves of anxiety... chest pain, coughing), which seem to dissipate with sublingual b12 and Vit C (as long as I stay in bed and don't move around).  My lymph nodes in my left arm, shoulder and neck are swollen and very tender....

Skin Tag Wierdness

Sometime between 14 to 7 days ago, virtually all the skin tags around my neck and shoulders turned into flat brownish patches. Now there's just pink, new skin like a small sore is healed where many of them were. I think they're gone!

I noticed it a week ago. I had just removed a particularly annoying one the week before that. I was checking how it was healing, and here I was covered with these dry, brownish patches where all the others had been. I showed Dianna, and she confirmed it.

I suppose my immunei system is recovering enough to keep the HPV suppressed again. I'm going to take it as a sign of my improving health. I've never heard of this, so thought I'd better record it. If they come back, I'll post here again and let everyone know.


Hi all, first appologize for my English, I am writing this mail from small country in Europe (The Czech Republic) and must admit am reading these sites for a while now. I must say I am so glad to see a way to cure which works and am even more amazed it is on internet. Unfortunatly my doctors do not share such exitement with me but I am sure after some time they will understand (once they are willing to open eyes and mind).

Help I am so confused

I am still trying to get a grasp on Chlamydia Pneumoniae, I just found out on 4-11-07.  But I have been sick for awhile  Cry.  I am just starting Antibioticsi again......eeeeek Foot in mouth.  My symptoms have been sinus infectionsi and uppper respitory infections , Phlaringitis, Broncotitis, Asthmai.  In and out of the Dr. office the month of April, and my throat swelled shut I could go on and on.  I ended up at an Infetious disease Dr.

Low IgG and IgM and Intravenous Immunoglobulin

Hi everyone,

Part of the bloodwork that I had indicated that I have several deficiencies in my immunoglobulins.  Specifically, I have a very low IgM, IgG3, and IgG4. (My total IgG looks normal, but those two subclasses are below normal levels.)

Have any of you had any tests with those sorts of results or any other Ig deficiency?  Have the tests improved because of/during your time on these antibiotics?

Do the IV antibodies have any chance at all at getting at the cpni inside cells?  Hmm... also, if it does get to them, do I run some sort of risk by having them go nuts on the cpn?

If you have had experience in general with IVIG, I would like to know how you responded.

I believe my doc is willing to treat me with intravenous immunoglobulins to bring the IgG up.  However, if the IgG is low because of CPN or something like it, I'll definitely need to keep on the abxi.  However, I'm scratching my head as to how to tell the difference between the IVIG fixing me and the abxi fixing me. (I have read stories of people who only needed one or two infusions and they were actually completely "cured"... it seemed that their body just needed the temporary boost to get their own systems going...)


Hi CPNers,  My basic disorder is fibromyalgiai which many doctors think carries the autoimmune factor.  I've had sporadic bouts with it since 1989.  Fibro symptoms are heavy muscular pain, fatigue, brain fog and itchiness.  The present acute attack began in 10/06, brought on by mega stress factors in my life.  When I failed to respond to gamma globulin injections and home treatment, and instead worsened, my doctor ordered a CPN test which came back positive on 11/7/06.  The test further indicated that I'd had CPN for years, but I never felt CPN symptoms before this.  I've praised my doctor for being so knowledgeable on CPN.  He visits CPNHELP.ORG frequently.

This year I had a 5-month bout of severe exhaustion, undiagnosed; coulcn't do anything nor go anywhere.  In 2004 I had 7 weeks of even more severe exhaustion, undiagnosed.  I wonder if the strange exhaustion was caused by CPN.

Viruses as cause or co-factors: Viral Henchmen in disease

The question of viral causes or co-factors comes up often, as most of the diseasesi for which one might use the CAPi to treat for Chlamydia pneumoniae have research which has found viral components as well.

David Wheldoni tackles this question on his web site, with his usual clarity of discussion and so well founded in his ready grasp of the scientific literature. Click the link below for his web page:

David Wheldon on "Viral Henchmen"<




CPn Tx and my recent labs...(Attn: Bio nerds and CFIDS folks...)

I would love any help, suggestions or advice regarding the following:

1. My most recent labs show Vitamin Di way under normal (despite supplementation with cholecalciferol). My result was 15 where 20-200 is normal. Does CPni treatment *deplete* Vitamin D or increase the need for Vitamin D in some way I don't understand?

2. I also compared my most recent labs to some from pre-CPn treatment. The counts of neutrophils and monocytes have dropped significantly, they went from normal to very low normal.  My absolute monocyte count has dropped in half and my absolute neutrophil count has dropped by about 60%.

I'm not getting any colds, flus, or immune-related problems as of yet; in fact I have had a reduction in such since beginning the CAPi, but these labs are distressing- if they are meaningful in any way, which I am certainly not sure of.

Oral Bacteria Linked to Uterine Infections and Preterm Birth

While this is not Cpni, I felt it was an important related finding as it demonstrates infectious bacterial source behind a previously overlooked cause in a phenomena (look at the Cpn & Animal materials on our site to appreciate how much Cpn could be linked to spontaneous abortions and miscarraige). It also suggests that, like Cpn, blood findings are not especially useful to detect infection. In this case the researcher notes:

"The bacteria were not detected in the patient's blood, but they had
likely been cleared from the blood by the immune system before they
could be detected," Dr. Han said.

Many relevant parallels.

"The study is an eye-opener," Dr. Han said. "It shows that oral
bacteria can get into the uterus."

      bacterium genus Bergeyella
      Ureaplasma urealyticum
      Mycoplasma hominis

Oral Bacteria Linked to Uterine Infectionsi and Preterm Birth
By Jeff Minerd, MedPage Today Staff Writer
Reviewed by Zalman S. Agus, MD; Emeritus Professor at the University
of Pennsylvania School of Medicine.
MedPage Today - Little Falls,NJ,USA - April 06, 2006<

CLEVELAND, April 6 - The first hard evidence has been uncovered that
bacteria in the mouth may find their way to the uterus, causing
uterine infections that can lead to preterm birth in pregnant women.

A newly discovered and as yet unnamed species of the bacterium genus
Bergeyella was found in the mouth and amniotic fluid of a woman with
a uterine infection who gave birth prematurely (24 weeks), reported
microbiologist Yiping W. Han, Ph.D., of Case Western Reserve here.

However, the bacterium was not detected in a vaginal swab, as might
be expected. The finding confirmed what some scientists have
suspected, that intrauterine infections don't always "ascend" from
the genital tract but can "descend" from the oral cavity, Dr. Han and
colleagues said in the April issue of the Journal of Clinical

The study included 19 pregnant women undergoing transabdominal
amniocentesis because of preterm labor or threatened preterm labor.
Amniotic fluid, blood samples, vaginal swabs, and oral swabs were
collected from each woman and analyzed for bacterial DNA via
polymerase chain reaction (PCRi) and nucleotide sequencing.

The species of Bergeyella was detected in the mouths of all 14 women
tested, but in the amniotic fluid of only one patient.

This woman had been diagnosed with a uterine infection based on an
elevated white blood cell count and a low glucose level in the
amniotic fluid. She went into labor, induced because of the
infection, and delivered her baby at 24 weeks' gestation. Subsequent
analysis of her placenta revealed severe and diffused
chorioamnionitis and fetal vasculitisi involving the umbilical cord
and chorionic plate, which was the presumed cause of her preterm

"Intrauterine infection with Bergeyella has never been reported
before. Where could the bacteria come from?" the investigators asked.
Because the bacteria were not detected in the vaginal tract, the
investigators hypothesized they were transmitted to the uterus from
the mouth via the bloodstream.

The bacteria were not detected in the patient's blood, but they had
likely been cleared from the blood by the immune system before they
could be detected, Dr. Han said.

Although periodontal disease has been implicated in preterm birth,
the patient showed no evidence of periodontal disease, the
researchers noted.

"The study is an eye-opener," Dr. Han said. "It shows that oral
bacteria can get into the uterus."

The study also suggested that more than the usual bacterial suspects
may be responsible for uterine infection and resulting preterm birth,
Dr. Han added. The usual suspects are known vaginal flora such as
Ureaplasma urealyticum or Mycoplasma hominis. But Bergeyella, a
little-known, rod-shaped, Gram-negative bacteria associated with dog
and cat bite wounds, had not been thought to be an important
component of the oral or vaginal flora.

One reason Bergeyella may have been overlooked previously is that it
is difficult to grow in culture. As much as 60% to 70% of oral
bacteria can not be detected by growing on culture. The current study
detected Bergeyella because it used PCR amplification of bacterial
DNA rather than traditional culturing techniques, Dr. Han said.

While suggestive, the study's findings do not yet support routine
analysis of pregnant women's oral or vaginal flora to identify those
who may be at risk for uterine infection, Dr. Han said.

"That is the question we want to ask now," she said. Her research is
examining whether particular components or oral or vaginal flora are
associated with increased risk for uterine infection or preterm

The mother and baby from the study are healthy and doing well, Dr.
Han said.


MedPage Today Action Points:   Explain to patients that while
suggestive, the study's findings do not support routine analysis of
pregnant women's oral or vaginal flora to identify those who may be
at risk for uterine infection
Primary source:  Journal of Clinical Microbiology
Source reference:   Yiping Han et al. Transmission of an uncultivated
Bergeyella strain from the oral cavity to amniotic fluid in a case of
preterm birth. Journal of Clinical Microbiology 2006; 44:1475-1483.
© 2004-6 MedPage Today, LLC. All Rights Reserved.

INH and Clearing Cpn from immune cells

Looking again at the patent materials and having an interest particularly in their discovery of INH as an antichlamydial agent I selected this excerpt because of it's importance in restoring immunei system functioning in those of us who have been immuno-compromised by Cpni. My daughter, for example, with terrible CFSi/FM, gets every virus which happens by and always gets a worse case of it. Prior to treatment, I also got colds frequently. Cpn infects macrophages and monocytes, rendering these infected immune cells less functional. If this is a predominant site of one's infection, then it stands to reason that your immune system sucks! Or, more accurately, is being sucked on... because Cpn functions parasitically by stealing the mitochondrial energy of the cells it infects.

I have highlighted and underlined some critical ideas in this excerpt. Thanks to Chuck Strattoni, et al for your brilliant and underappreciated discoveries:

The immune system, atherosclerosis and persisting infection

Vestn Ross Akad Med Nauk. 2005;(2):17-22. Related Articles, Links

[The immune system, atherosclerosis and persisting infection]

[Article in Russian]

Pigarevskii PV, Mal'tseva SV, Seliverstova VG.

The paper demonstrates that lymph nodes situated in the vicinity of magistral blood vessels are the source of immune and inflammatory response to LDL as the main pathogenetic factor in atherosclerosis. The activation of T-cell-mediated immunity takes place in them at the very early stages of the disease, resulting in forming of CD4+T-lymphocytes, activated mononuclear cells and immunostabilizing B-lymphocytes. The cell changes in lymph nodes correlate with the severity of atherosclerotic lesions in the vessel intima and closely reflect the peculiarities of immune inflammation development in fatty streaks and atherosclerotic plaques in human atherogenesis. A paradoxical reaction was observed in cases with Chlamydia pneumoniae found in the wall of aorta and paraaortal lymph nodes. No evident immune response on the part of immunocompetent cells took place, but, on the contrary, the function of mononuclear cells, including T-lymphocytes, was suppressed. This phenomenon may be explained by the fact that intracellulari localization of Chlamydia pneumoniae hides it from immune system control or by the possible microorganism capability of direct immunosuppressive influence on lymphoid cells both in the blood vessel wall and in regional lymph nodes.

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