Cryptic form

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Under stringent conditions, RB's in the cell can transform for survival into an low-metabolizing and non-replicating form which is not killed by regular antibiotics.

Antibiotics to be available without prescription

This is the news:  In England, possible antibioticsi to be sold over the counter, to treat CHLAMYDIA!

This is the story form http://www.guardian.co.uk/society/2008/aug/06/health<

Oral antibiotics are to be made available for the first time without doctor's prescription under guidelines approved yesterday by the medicines regulator.

A pill to treat chlamydia, the most commonly diagnosed sexually transmitted infection, will become available for purchase in pharmacies across England later this year.

Pulse 2...(five days post-pulse)

Blogging for the record....  My second pulse was  1-250 mg of Tinii for 4 days.... May 24-27, 2008

1.   First two days I noticed an increase in energy

2.  Day 3  my LEFT knee and hip became painful and stiff. Up until this point I have not experienced problems with my left leg, it's been all in my right knee and sacriliac .   I could barely walk and was unable to go up or down stairs.   I still have major problems with my right leg - knee (can't squat or bend, difficulty walking up stairs.)

2.  Again increase in coughing... as well as chest congestion - benedryl helps

3.  Red rimmed/watery eyes.

4.  Third day I had a really bad headache (and I usually don't get headaches)

D-Ribose Bringing CPn Out Of Cryptic Form?

Paula has been starting to use d-ribose primarily to increase energy and reduce porphyrin production.

As you may know, she does have a lot of trouble tollerating new supplementsi which is why we add anything new, very slowly.

She is currently putting 1.25 grams of powder into a 75ml bottle of water and taking a few slogs.  Over the past couple of days, her tollerance level has increased, as previously she would get a large increase in fatigue when taking it.  She has attempted to take ribose a few times these last couple of weeks, but had reactions to it.

Reactivation of CPn in Cortisone Treated Mice

Reactivation of Chlamydia pneumoniae infection in mice by cortisone treatment.
K Laitinen, A L Laurila, M Leinonen, and P Saikku
National Public Health Institute, Helsinki, Finland.

Infect Immun. 1996 April; 64(4): 1488–1490

Reactivation of Chlamydia pneumoniae infection was studied by inducing immunosuppression by cortisone acetate treatment given every other day for 14 days in intranasally infected NIH/s mice. The treatment started 2 or 4 weeks after primary infection, when no C. pneumoniae was detected. C. pneumoniae could be recovered from the lung cultures on days 7 and 9 in 10 and 60% of the mice, respectively, when cortisone treatment was begun 30 days after infection. These results confirm the persistent nature of C. pneumoniae infection.

Continual Blood in Urine (from Kidneys)

I have been monitored for microscopic blood in my urine since early 2000. The doctor I was treating with back home always seemed to believe it was due to celiac/gluten intolerance as we could never find anything conclusive.... hmmm.. cpni???

I am now out of state with a urologist who has been treating me for 4 years.  Every time I have had an appointment there has been blood in my urine.  

 I just came from a visit with her (my urologist).... all has been tested (cystoscopy, kidney x-rays, urine cytology). Today, I pushed her for a "what are we going to do or conclude" about this?  The only confirmation that we have is that:

1) there are no cancerous or squamous cells; (which is great)  and,

Addendum - Pulse #1 - Day 21

Addendum to my blog.  It's day 21 post pulse. I am depressed and sick and tired of being sick and tired.  I guess it's finally hit.  I only took 1- 250 mg of Tindamax for 2 days.  Nothing really happened until now.  I was experiencing pelvic/gut pain but kept writing it off to the pulse.  so I then went the route of gyn and  urologist which has led me to:

1) I have a bladder infection  -- was prescribed Nitrofurantoin 100 mg BIDi

2) Per gyn - I  have BV and gyn wants me to use Clindesse -- I have not administered it yet as I am concerned I'll be on antibiotic overload and could possibly cause another pulse or yeasst.  I have no idea how it would interact with CPNi.

First Pulse (finally) for the record..

Haven't been posting lately-- not much to note re improvements (or I should say lack of -- but  continue onward!) . I still have extreme CFSi and FM which keeps me physically down most of the week... no driving, shopping, housework, etc.  Frustrating, expecially now that the weather is warm. 

One of the few positives  (right now anyway) after being on the dual CAPi for a year is that my body no longer has that  "sick, sick" feeling.... just the extreme fatigue.   I do have occasional days that pop up maybe once a month  ... "pseudo normalcy".  

Interruption of ABX – Waiting for Biopsies

Sunday night I went to the emergency room with severe abdominal pain (upper/lower left quadrant, front and back – [as an aside, I have experienced pain on my left side since almost the beginning of my ABXi in April of last year –2007].  I kept contributing the discomfort to possibly die off and/or my spleen.  My dr. could never find anything on x-rays or a cat scan, so I just kept plodding along, as it was not intolerable.

Prevention Of Cell Death - How Long?

Just a general question really.  Just out of interest, once the cpni bug goes into cryptic stage and prevents the cell's natural death - how long can the cell stay as a zombie?

Presumably the prevention of cell deathi cannot last forever? How long?

For example if someone only used the macroglide antibioticsi and didn't touch the Flagyli etc, would the bug be forced to come out of hibernation eventually and the cell die?

Or is it only Flagyl that can get it at the cryptic stage like a shotgun to a zombie's head?

Don't worry, this isn't something we are considering - it's just a question to enhance knowledge.

btw I do like my zombies and are looking forward to the new George A Romero zombie movie "Diary of the Dead"

tryptophan

Is it good or bad?

Morgellons Disease - You Think We with CPN Have a Hard Time Convincing our Doc's!!! - this is interesting and sad

I was scurfing the internet about a topic of interest to me and ended up in links pertaining to Morgellons Disease -- has anyone heard of this?  I hadn't but my heart went out to those suffering because  no one believes them and they are being labeled with "Delusions of Parasitosis".  We all know how most of the mainstream medical field views CPNi and CAP can you imagine what it is like for these people?   One doctor (below) has noticed improvement in the symptoms of those treated with antibioticsi -- and some think it's a co-infection with Lyme.  But for now -- it's all in their "heads" by most allopatic's.  Even the CDC is not recognizing it.

Bromelain as temporary substitute for Flagyl or Tinactin

I've been looking through this site Since June 24, 2007 and as a result started NACi 1200 mgs/day several days after beginning doxycycline 400 mg per day (200mg with breakfast and supper) for Cpni.  I have now been on this combination for 10 weeks.  They first two weeks were difficult and l was down more than up however since then I have reduced brain fog, and improving energy and some ability to follow through on tasks that had overwhelmed me and my short term memory has begun to improve and I am making some headway in picking up the details of day to day life.  

Role of tryptophan supplementation in the treatment of chlamydia

Med Hypotheses. 2007;68(2):278-80. Epub 2006 Oct 11. Role of Tryptophan supplementation in the treatment of Chlamydia.Singla M. Department of Pediatrics, University of Illinois, 840 S. Wood St., CSB Chicago, IL 60612, USA. msingla@uic.edu<

Thinking outside the box-is there a future better way?

As one reads the entries on this site you learn of many challenges and hardships faced as one deals with the numerous reactions to the protocol. Many are due to the die off aspects.

It makes me wonder if somewhere in the future there could be another way that might be more tolerable and perhaps quicker. I'd like to toss out a few thoughts for different approaches that maybe someday might work(or not). Given the vast knowledge and experience of the members of this site, I invite and encourage other thoughts. Maybe there is an audience out there that might explore some of these ideas if they were captured here - you know - "plant the seed" or "put a bug in ones ear".

Here goes:

Help I am so confused

I am still trying to get a grasp on Chlamydia Pneumoniae, I just found out on 4-11-07.  But I have been sick for awhile  Cry.  I am just starting Antibioticsi again......eeeeek Foot in mouth.  My symptoms have been sinus infectionsi and uppper respitory infections , Phlaringitis, Broncotitis, Asthmai.  In and out of the Dr. office the month of April, and my throat swelled shut I could go on and on.  I ended up at an Infetious disease Dr.

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