Last Wednesday, I decided to start the InterFase Plus for the treatment of biofilms.  I was curious to see what, if any, type of reaction I would have.  The recommended dosage (on the bottle) is 2-8 capsules per day.   Additionally, I have a schedule obtained from an autism parent given to her by the autism doc, Dr. McCandless, but it is too agressive IMOⁱ, for me so I decided to only take it on M/W/F,  the days I take both Azith and Doxyⁱ. (I switched back to Azith, from Roxi January 2010). 

Kim's just starting her December 2009 pulse and she's "Out the Gate Early".  Meaning, Flagyl "fun" started up on day-1 of the pulse.  I've read that folks on Tiniⁱ have less of this and I came here today to think about it.  First here's a couple links to RxList:

Flagyl (Metronidazole) and Tindamax (Tinidazole)

I thought it was interesting that both of them had peripheral neuropathy listed as side effects.

Being a good cpnhelp'er I did a search and here are links I found:

On this forum someone wrote:

Does the the cryptic load accumulates over time. I had an image of all the bacteria changing from L-Form -> Cryptic then all from Cryptic -> L-Form. From what I've experienced I'm thinking that everytime the bacteria shift to Cryptic that not all of them shift back to L-Form when the conditions warrant. This could explain why some people need many many rounds of Flagylⁱ/Tiniⁱ to eraditate this form and someneed much less.

For my records here….. I started pulse #12 on Sunday, October 4th.  I have been tolerating my pulses (for the most part) decently.   The first 2 days the left side of my head felt clogged with cement.  My left ear, eye, lymph nodes, sinus were painful.  Right knee painful.   Total inability to concentrate... first 3 days I felt as if I were in "suspended animation" and all I really did was “zone out” and stay in the house.

My previous LLMD who was my CAPⁱ prescriber moved out of state and I transitioned to another dr in the same practice group. Yesterday was my first appt. I was a bit apprehensive to change the dr but I am happy now I must say.

My new dr has a different approach to the disease in terms of that he treats whole body. If my previous provider just gave me CAP rx, this dr wants to address all my conditions - hypoT, hypertensionⁱ, nutritional issues, wants to check heavy metals as well. He even asked if I have a ObGyn and do regular pap smears.

An old one (1998) but still a good (IMOⁱ) reference:

Evidence of Systemic Dissemination of Chlamydia pneumoniae via Macrophages
in the Mouse

Below is a small paragraph from Lyme disease dxⁱ/tx guidelines of Dr. Burrascano that struck me as I was reading, anyone heard of Flagylⁱ/tetracycline interactions?

Intermittant Thereapy~~~ There recently have been quite a few who have gone to intermittant therapy (hurray!).  I know in recent discussions comments are made "to refer back to their individual posts" to see what that consists of.  It is difficult sometimes to query this site for such specific information re each member.  

 Chanced upon this older thread started in June2006  I am bumping it up; http://www.cpnhelp.org/flagylvstinidazole for reference and the original thread in context.

I am extracting a post that is very interesting to me and my situation.  Hope that some others may find it an interesting read as well.  Louise

Yesterday I took my first Flagylⁱ 250 mg, no reaction. Today took 2 x 250 mg and started to wonder, is it possible to develop resistance to Flagyl if taken in small doses? I'll be increasing the dose in future pulses if tolerated. My dr wants me to take 500 mg x 2/day for 14 days a month eventually.

I'm trying to find a journal article or other authoritative source that explains the cryptic/third state (what it's called here at CPnhelp) of CPn.  I've found that there are a lot of kinds of chlamydia and there's little out there about cryptic state.  There is stuff called plasmid, but I can't tell what that is.

My frustration is in that there are plenty of discussions of Elementary Bodies and Reticular Bodies and lots of diagrams and info on these.  But, there is very little on Cryptic and I'd like to be able to show this to others with the supporting literature.

Here's the best links I can find right now, but they are not really about Cryptic Cpn.