Asthma

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Asthma

The Current Regimen (and rationale :-)

On waking: take all antibioticsi for the day.
Rational: As much as I would like to spread them over the course of the day, it becomes difficult to fit in the minerals and probiotics that need to be taken AWAY from them.
Negative: the PDR says it is OK to take them with food which is good because the doxyi makes me feel puke-y with water alone, although azith is OK with water. I take them with my giant cup of coffee which also contains about half a cup of milk – I know calcium is not good with the antibiotics but the PDR says it reduces the effectiveness just a bit . . . and I am small – 110 pounds only so I am thinking it is OK.
 
The supplementsi are all in one cupboard, each bottle marked with a label saying how many capsules and how often to take i.e. “Two x 2.”

Anyone out there with Asthma?

Just wanted to know if anti-biotics have helped anyone with asthma? Not just asthma someone contacted over the past couple years. I had asthma since I was a baby and want to know if there is any success stories out there.

Thanks!

Brian

Some Ramblings on the Process

Started the AsthmaStory protocol two and a half months ago - did 1000 azith. once per week. Had some deep aches in hips and low back - better with exercise but nothing else remarkable.

The BackStory - Have had asthma most of my life but with little or no need for medication. Two years ago, after a month in Tucson, AZ, returned home rested and relaxed...and within a month my asthma went nuts. Spent a year using tons of Ventolin. Finally went to Mayo and had a lot of expensive asthma testing done with no answers other than to use Advair - yuck!

Anywho - tried the azith., then found this site. Took two weeks off the azith. and started the supplementsi. Dang - that has got to be the difficult  part of the cure - those big, honkin' handfulls of vitaminsi :-)

This past Sunday, started the doxyi - 100 x2 - one morning and one at night. Added in the lower dose Azith (250 - 3x per week - morning).

Asthma

I hope I am doing this Blog the right way. Does anyone here have asthma? I have been on Zithi for about 10 weeks now. I take 1000 MGs once a week. Does anyone here know if I should add another antibiotic?

Eleven years sheparded by the drug dependent medical/industrial complex and my attempts to escape its clutches....

Thanks to Janice C., Jim K., and Katman for the greetings and advice!

 I have had asthmatic symptoms for 11 years, my wife has developed astmatic symptoms in the last three years, and my oldest child, now 12, uses an inhaler about four times a year since he was 8. My youngest, now 8, has never shown symptoms.

Eleven years ago I quite smoking for the fourth and final time. After each time I always would get some kind of bronchial cold. I don't usually get ill, but I'm sure the clearing of my lungs laid bare the weakened cells to any predatory microorganisms hanging around. The bronchial distress went on for over a month and I went to the hospital to see if it was pneumonia. They stuck an albuterol mister in my mouth and after 45 minutes my lungs had opened up, though I was still uncomfortable. They said I had Reactive Airway Disease (RAD) or "twitchy lungs" and gave me a steroid inhaler. I ditched it (no steroids for me!), but my asthma symtoms got increasingly worse, until I was forced by abject misery to adopt the chemical relief. Albuterol, steroids inhalers, prednisone. Then Albuterol, Advair. and prednisone. Now it's Singular, Asthmacort, and predinisone. Cash cows for the drug industry. Customers who are told "there is no cure for asthma, but can be controlled by drugs" ensuring a loyal perpetual income from the chronically ill. But the medicines are hurting me over time. And they cost a lot, especially trips to the emergency room because my insurance only covers me for doctors 120 miles away where my job is (I work mainly from home). I can't afford the more expensive flexible plan plus my county doesn't accept PPOs anyway. Aww. Boring insurance blues crap, so I'll spare you any more on that.

Constricted breathing, constant production of colored mucus, occasional visits to the emergency room, though I was never in great danger. Excercise helped even with the dreaded "excercise induced " symptoms. But how far could I carry a child in an emergency before succumbing to an attack? What would happen if access to medicines were removed? Thoughts that so many people far worse off than I have pondered. But what frustrates me is how my thoughts on the matter have been dismissed by the specialists. The emergency room doctors are much more open minded and know more about current medical information. My asthma doctor dismissed my comments about bacterial causes with an "Oh, they've been saying that for years." and then changed the subject to the drugs available. Gee. Maybe there's a reason they've been saying it and a reason the drug and insurance companies perfer his choice of treatment; perpetual drug cosumption.  I was amused to see the Wikipedia definition ponder the reasons that the medical establishment has been ignoring research into the link between CP and the many diseasesi for the last five years (or more). Thier guess; no money in nonpatentable drugs.

And my asthma is chronic. And it's always there. Even through the relief of prednisone I feel it in the cells of my lungs. Only ONE thing has ever removed my symtoms completey, if temporarily; antibioticsi.

20 days in...

Feeling pretty good now. The viral infection cleared within 3-4 days. My temperature fluctuation has standardardised on a slightly warmer feeling all over. Still getting reduced night-sweats. I felt like someone was pulling at my ribcage for a couple of days, and my chest is still a little sore, but nothing like it was.

For the last two days in particular, I've felt really very good indeed. More energy, mental focus and enthusiasm. I won't count my chickens, but I'm also getting some colour back into my face.

Something else which I've noticed is that an ever-present (so much so that I didn't really even acknowledge it anymore) tickle in the back of my throat has cleared. Explain that if you can!

Carrying on with the yoghurt and probiotics, as well as NACi 2 x 1200mg, and they are, of course, helping greatly. I spoke to my G.P's surgery this morning and they have a prescription waiting for me, explaining that I'll start the first pulse of Flagyl (metronidazolei) in January. That's good. Didn't fancy a dreadful Christmas after last year's episode of the whole house having some sort of r.t. infection, then D&V over Christmas/New Year!

12 days on... somewhat of a result!

Still off work. Lungs are a bit sore and coughy/phlegmy this morning.

I managed to get in to see my GP this morning (as opposed to next month), and found out that all my concerns had been for naught. He is only too willing to help and prescribe the abxi. So, all in all, I'm ecstatic about that. Makes it all so much easier to know that you have him on board.

One other small thing of note. I also managed to get some ointment for my eczema. I've has a nasty patch on left ankle and leg for 5 years There's only one cream that has really ever worked for any length of time, and that's Betnovate-N. Its active ingredient is neomycin. I had always assumed that it was an anti-fungal, but apparently not. It's anti-bacterial, and he was interested to learn that this works, considering everything else he was being asked to prescribe.

11 Days on... feeling defensive...

Not in work today. Feeling rough. Have been sneezing lots and am very snotty. I suspect it's viral. It would have to be! Nice dripping nose. Over the last few days, my temperature has been all over the place with sweats during the day and night, and mild headaches as well. Feel fatigued today.

 I also think I'm battling with candida at the moment (off and on, I have a coated tongue), and have been attempting to respond in kind with probiotics and yoghurt. Feel better today than I did yesterday.

 In other news, the numbness in my left hand appears slightly decreased, but that could be down to a lower ambient temperature at the moment, being that autumn is underway. For me, heat is a killer for numbness.

I have suffered from eczema for about five years, and there is some decrease, although it's too soon to read anything into that. I won't know for sure whether it's all helping for a few more weeks.

4 days on...

Saw David Wheldoni on 15th September 2006. A truly heart-warming experience. 

4 days on the CAPi now. For RR-MSi<

 After 2 days on doxycycline, I noticed I could stand with less stiffness, which I am imagining could be due to the anti-inflammatory effect of the antibiotic. Pins and needles are already reduced!

 This morning, I was somewhat foolish and tried the doxycycline and NACi on an empty stomach. Not a good idea. Quite nauseous. Won't do that again in a hurry.

 No real die-off symptoms yet. I have a feeling I may have kept my bacterial loadi down over the years with constant vit c and other antioxidantsi. I can't help but feel my MS would be worse than it is if I hadn't supplemented so furiously over the last 3 years.

 Anyway, I am going to try and keep this journal ongoing. Probably in weekly installments.

Cpn treatment experience with asthma/chronic sinusitis?

I have two friends about to begin the cpni protocol; one has FM and asthma; the other has severe asthma and chronic sinusitis; both have tested positive to cpn.  Does anyone have experience with effects in treatment with primary illness being asthma?  What to expect?

Secondary outcomes of a pilot randomized trial of azithromycin treatment for asthma

 PLoS Clin Trials. 2006 Jun;1(2):e11. Epub 2006 Jun 30. 
Secondary outcomes of a pilot randomized trial of azithromycin treatment for asthma.

Hahn DL,
Plane MB,
Mahdi OS,
Byrne GI.
Dean Medical Center, East Clinic, Madison, Wisconsin, United States of America.
OBJECTIVES: The respiratory pathogen Chlamydia pneumoniae (C. pneumoniae) produces acute and chronic lung infectionsi and is associated with asthma. Evidence for effectiveness of antichlamydial antibioticsi in asthma is limited. The primary objective of this pilot study was to investigate the feasibility of performing an asthma clinical trial in practice settings where most asthma is encountered and managed. The secondary objectives were to investigate (1) whether azithromycin treatment would affect any asthma outcomes and (2) whether C. pneumoniae serologyi would be related to outcomes. This report presents the secondary results. DESIGN: Randomized, placebo-controlled, blinded (participants, physicians, study personnel, data analysts), allocation-concealed parallel group clinical trial. SETTING: Community-based health-care settings located in four states and one Canadian province. PARTICIPANTS: Adults with stable, persistent asthma. INTERVENTIONS: Azithromycin (six weekly doses) or identical matching placebo, plus usual community care. OUTCOME MEASURES: Juniper Asthma Quality of Life Questionnaire (Juniper AQLQ), symptom, and medication changes from baseline (pretreatment) to 3 mo posttreatment (follow-up); C. pneumoniae IgGi and IgA antibodies at baseline and follow-up. RESULTS: Juniper AQLQ improved by 0.25 (95% confidence interval; -0.3, 0.8) units, overall asthma symptoms improved by 0.68 (0.1, 1.3) units, and rescue inhaler use decreased by 0.59 (-0.5, 1.6) daily administrations in azithromycin-treated compared to placebo-treated participants. Baseline IgA antibodies were positively associated with worsening overall asthma symptoms at follow-up (p = 0.04), but IgG was not (p = 0.63). Overall asthma symptom improvement attributable to azithromycin was 28% in high IgA participants versus 12% in low IgA participants (p for interaction = 0.27). CONCLUSIONS: Azithromycin did not improve Juniper AQLQ but appeared to improve overall asthma symptoms. Larger community-based trials of antichlamydial antibiotics for asthma are warranted.

Asthma and CPn - link

Asthma and CPni link. (Apologies if this already posted). Thursday April 13th 2006 The Herald (Scotland) reported the following: "An antiobiotic used to combat a range of infectionsi could help those suffering serious asthma attacks, research has shown. Telithromycin, which treats bacterial infections such as sinitus, can speed recovery by three days, a study found."; "Patients were enrolled in the trial within 24 hours of a severe attack, after their usual medication failed to work effectiveley."; "...published yesterday in New England Journal of Medicine, involved 278 patients at 70 centres around the world, including St Mary's Hospital in London."; "They believe the effects may be a result of the drug's action on the bacteria Chlamydophilia pneumoniae and Mycoplasma pneumoniae. About 61% of patients tested positive for either or both bacteria, suggesting their presence may increase the severity of the attacks."

Unpublished
n/a

Diseases associated with Cpn: the exhaustive list

I have culled from Mitchell & Stratton patent #6,884,784 an exhaustive list of diseasesi where Cpni has been implicated as a possible cause or co-factor (reference: Mitchell & Stratton patent #6,884,784):

Diseases where an association has been discovered between chronic Chlamydia infection of body fluids and/or tissues with several disease syndromes of previously unknown etiology in humans which respond to unique antichlamydial regimens include:

Editorial comment: Strong findings from their research. If you have any of these it suggests to me that at least an empirical course of the combination antibiotic therapy is strongly indicated, with or without serologyi.


Multiple Sclerosis (MSi)
Rheumatoid Arthritis (RA)
Inflammatory Bowel Diseasei (IBD)
Interstitial Cystitisi (IC)
Fibromyalgiai (FM)
Autonomic nervous dysfunction (AND neural-mediated hypotension);
Pyoderma Gangrenosum (PG)
Chronic Fatigue (CF) and Chronic Fatigue Syndromei (CFSi).

Connect the Dots

I am trying to connect the dots, and was wondering if I could get an opinion from some of you who have been here a while, and know more about CPni.  Several years ago, and I can pinpoint it to within a couple of months, I began feeling "not right".  I was first dxi with pernicious anemia after complaining of brain fog and fatigue, then irritable bowel syndrome for chronic unrremitting diarrhea.  These were followed by numbness in two toes, which the neuroi determined was caused by diabetic nueropathy (after three glucose tests, one came up a little off, and he dx'd glucose intolerance).  I beleive I have glucose intolerance, but diabetic nueropathy from it?  Anyway, after that, psoriasis, which I had had problems with for years without knowing what it w
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