Cpnhelp.org

Now, I am really confused about resveratrol. An acquaintance of my husband (who is a microbiologist and a professor of neurophysiology) just told me that latest research is proving that it is the small amount of alcohol in wine, rather than resveratrol that provides benefit. I should have asked him for references, because all I can find are studies such as these:  LINK  and  LINK

--Minai

Minai,

 the information you provided deal with alcohol in red wine rather than resveratrol. They don't mention Cpnⁱ, as well: so they might not be as relevant in our case.

This study investigates the effect of resveratrol and curcumin against Cpn; and here are some other notes regarding resveratrol in red wine and Cpn:

January 14, 2004

French paradox explained?

A letter to the December 2003 issue of the journal Atherosclerosis offered a possible explanation for the so-called French paradox, which is so named because of the apparent paradox of the relatively low incidence of heart diseaseⁱ among the French, who consume a greater amount of fatty foods than the populations of many other countries. It has been hypothesized that the frequent consumption of red wine by the French may be responsible for offering a degree of protection against coronary heart disease (CHD).

Researchers at the University of Illinois at Chicago studied the effect of a methanol soluble pinor noir red wine extract, a concentrated extract, and resveratrol from red wine on two strains of cultured cells infected with Chlamydia pneumoniae, a bacterium responsible for up to 30 percent of acute respiratory tract infectionsⁱ that has also been found to be associated with atherosclerotic plaque development and coronary heart disease. Both the concentrated pinot noir extract and the resveratrol proved to be active against the two Chlamydia strains.

The first time that red wine extracts and resveratrol had been reported to be active against a human pathogen was in 2001, when two of the researchers involved in the current study found that the compounds inhibited the growth of the bacterium, Helicobacter pylori. The authors conclude that, “the French Paradox may be due in part to the beneficial effects of red wine consumption on development and progression of CHD through its antimicrobial activity on C. pneumoniae .” ( Schriever C et al, “Red wine, resveratrol , Chlamydia pneumoniae and the French connection,” Atherosclerosis 171 (2003) 379-380.

 A little red wine won't probably hurt anybody who enjoys it: how effective it might be against Cpn (and heart attack, stoke, atherosclerosis ).... who knows?

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< SPMSⁱ - EDSSⁱ 7 > < NACⁱ 600mg X 2, Doxyⁱ 100 mg X 2, Azith 250 mg MWF, Flagylⁱ pulses, green tea, curcumin, flavonoids + all the supplementsⁱ listed on Wheldon's Protocol (and possibly more) >

Unfortunately a little red wine won't give you much in the way of resveratrol. You have to chug down gallons of the stuff to get any appreciable levels of resveratrol (see my post above).

p.s. thanks for shortening the science direct url you posted! 

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Hunter: Don't think - experiment

p.s. any chance of shortening the science direct url you posted?

Ok, I tried the best I could. Sorry, I'm new to this site, and still learning the peculiar formatting techniques....

Anyway, I agree with you: several foods (probably most of them) contain substances that can have an influence on human health (whether good or bad). But if you expect remarkable health improvement out of the tiny quantities of "active ingredients" found in food (or drink), you'll have to get huge amount of them (which will probably hurt you, somehow).

Specific supplementsⁱ (derived from foods) may provide some benefit, in some cases.

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< SPMSⁱ - EDSSⁱ 7 > < NACⁱ 600mg X 2, Doxyⁱ 100 mg X 2, Azith 250 mg MWF, Flagylⁱ pulses, green tea, curcumin, flavonoids + all the supplementsⁱ listed on Wheldon's Protocol (and possibly more) >

I'd posted this a while back, but has some relevance to this discussion. There is a patent,

"Plan-derived and synthetic phenolic compounds and plant extracts, effective in
the treatment and prevention of chlamydial infectionsⁱ " (there is a mispelling of "Plant" in the title, but that's how it is listed) United States Patent 20040058983

These compounds, such as simple aromates, phenols, coumarins, lignans, lignins and flavonoids are obtained from products of the vegetable kingdom such as fruits and vegetables, especially citrus fruits, vegetea, red wines etc.

 Mind you, these are all found through active against Cpnⁱ through cell culture, so what reaches your actual cells is questionable. Still, reading it is informative about chlamydia in general. From the resveratrol/curcumin study it seems that resveratrol may be a better inhibitor in supplement concentration doses.

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CAPⁱ for Cpnⁱ 11/04. Dxⁱ: 25yrs CFSⁱ & FMSⁱ. Currently: 250 aithromycin mwf, doxycycline 100mg BIDⁱ, Tiniⁱ 1000mg/day pulses; Vit D2000 units, T4 & T3, 12mg Iodoral

The patent you mentioned was apparently registered by some of the authors  (three out of five) of the study  "Inhibitory effect of dietary phenolic compounds on Chlamydia pneumoniae in cell cultures".

And, yes: you are right.
No one knows for sure how much anyone has to eat/drink to achieve effective concentrations in human cells.
I'm just wondering if there are "upper safe limits" for, let's say, resveratrol when taken as a supplement (I'm sure anybody knows his or her "upper safe limit" for red wine! ).

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< SPMSⁱ - EDSSⁱ 7 > < NACⁱ 600mg X 2, Doxyⁱ 100 mg X 2, Azith 250 mg MWF, Flagylⁱ pulses, green tea, curcumin, flavonoids + all the supplementsⁱ listed on Wheldon's Protocol (and possibly more) >

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6-07WheldonCAP CFS20+yr

(11-29-07 started Cholestyramine HS PRNⁱ x 7d for porphyrin+endotoxinsⁱ removal)

Check out Louise's Blog at; http://www.cpnhelp.org/blog/louise for the details of my treatment adventure!

I just began taking resveratrol a few months ago. I love the way it smells.I bought the Source Naturals brand also. Lots of good reports about it in the Life Extension magazine.

I rarely drink anymore so taking the supplement is the best way for me.

Also began taking Flax Seed Oil this week. Stirring it into my morning yogurt or smoothies. Noticed feeling warmer, less inflammationⁱ and more energy. I already take fish oils but feel like adding a different type of Omega 3 is a good strategy.

Raven

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Feeling 95% well-going for 100. Still testing + for Cpnⁱ. CAPⁱ since 8-05 for Cpn/Mycoplasma P.for MSⁱ and/or CFSⁱ. Also EBVⁱ and HHV6. Amoxy,Doxyⁱ, Azith, Tiniⁱ pulses. NACⁱ, BHRT, MethyB12 injections

The Wine Doctor - the world's first anti-oxidant wine with 100mg/L of revervatrol per bottle....

http://news.ninemsn.com.au/health/697410/wine-cleans-bloods-vessels-as-y...

 http://www.agroz.com.au/WINE/r&d/tastingNotes.php

"Dr Norrie has produced both a Chardonnay and a Shiraz with each having 100mg/L of resveratrol per bottle.

He said this was as much as is contained in 70 to 100 bottles of standard white wine or 15 to 20 bottles of standard red."

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Overlap syndrome: lupus, RAⁱ, MCTD/Scleroderma. Wheldon CAPⁱ Oct 03-Nov 04; Pulsed abxⁱ for 3.5 years. Restarted Wheldon CAP Nov 08. ABXⁱ daily: 200mgs Doxyⁱ, 300mgs Biaxsig, monthly 7-day Flagylⁱ pulses 1200mgs; Daily supps: CoQ10,  B Complex &  B12, Vit D

There's a lot of Reservatol brands out there now...this site is reviewing them: Reservatol Reviews

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KEREM'S TAKECARER;

Suspıcıon of MSⁱ (transient nystagmus during conjugated gaze on february 2008, blepharospazms and some optic complaints on february 2009-no plaque on MRI), Vit D3 started 400 IU and elevated to 2000 ıu ın 40 days.

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The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

RESERVATOL (RESVMAX)

I took the offer trial of reservatol (viv3lab ltd, resvmax) for a month didnt feel anything; the only thing that I could feel was that I was sleeping much later than usual and waking up earlier, but in the day I was feeling the lack of sleep.  But be aware of buying free trial, they charge me £79.00; because in small print they tell you that is you dont cancel the order after 15 days they will charge you this amount monthly!!! And worse is that they send me the bottle of a RESVMAX I didnt order, and they dont accept refund, they have this information in another web page that I missed! And looking price in other web site the rate price of this is about $15.00.

So if you want to try it be very very careful! read all the small print, because this free trial including pp have cost me £83.00!!!!