A sample letter to local doctor to convince of abx treatment

Jim,

This is a sample letter my Husband and I sent my doctor when discussing treatment of abxi [1] for MSi [2].  We thought you could post it somewhere here for others that need to write letters to their doctors.

We think it really helped. 

Dr. {xxxxxx},

I deeply appreciate your willingness to consider supervising me on a long-term, lose dose combination antibiotic regimen to treat my multiple sclerosis diagnosis.  I understand that this protocol is non-conventional, unproven, and is not without risks, including immediate or long-term serious adverse events from antibiotic use.

In spite of MS drug companies’ aggressive marketing messages, the published data show that the conventional disease modifying therapies provide minimal impact on disease progression.  While waiting for the announcement of a miracle drug that works I have actively searched for promising alternative therapies for over {N} years.  During this time I have learned to become very skeptical of the dozens of alternative theories and therapies I have come across.  I have proceeded with caution and have tried a limited number of alternative therapies with some encouraging but limited results.

The relapsing/remitting nature of MS and randomness of disease progression makes objective measurement of therapies difficult.  The stress relief, endorphin impact, and other placebo phenomenon’s also make evaluation challenging.  My understanding of these factors makes me leery of pure anecdotal testimonies, especially where someone has a profit motivation.

From my readings most MS researchers believe that they are dealing with an immunei [3] disorder.  Others believe the immune system attacking the myelini [4] sheath is a symptom of some other underlying cause of MS.  Unfortunately no one has yet discovered the root cause.  Persons are diagnosed with MS because of common symptoms and examination findings but there is convincing arguments that MS suffers as a whole may consist of sub-groups with different underlying causes such that certain therapies may be more effective for certain subsets.

As you well know some bacterial and viral infectionsi [5] share many of the same symptoms as MS.  I understand that I don’t have laboratory evidence of any current measurable infection requiring antibiotics.  I have read theories suggesting that some infections, especially long-term infections, may not be accurately detected by conventional lab tests.  The specific protocol I am asking you to supervise was specifically created to eradicate a CPNi [6] bacterial infection.  But this protocol is similar to that used to eradicate other infections as well.  Proof or identification of a specific infection is not my ultimate objective.  I am interested in empirically discovering if I can experience any disease progression reversal by use of antibiotics. 

During a prior appointment with you I first mentioned my interest in trying an antibiotic regimen.  I subsequently began taking several probiotic supplementsi [7] in preparation for beginning antibiotic therapy.  I would now like to start the antibiotic regimen.  In my last appointment you proposed alternating monthly the use of doxycycline and azithromycin.  But since, after further investigation, I read the importance of not cycling the doxycycline and azithromycin but after 3-4 weeks of starting doxycycline I should add azithromycin and take the two in combination.

Apparently the cyclical long-term stopping and starting use of the individual antibiotics will promote resistance rendering each ineffective.  Also, the protocol works four times more effectively by using both antibiotics in combination because of their synergistic effect.  Each antibiotic targets different steps in the bacterial protein synthesis pathway.  Their primary effect is not to directly kill bacteria but instead to diffuse their ability to replicate.  Apparently, the resistance is created thru replication (birthing) of new forms.  By disarming the replication ability in multiple forms the ability to create resistance is dampened.

The later addition of the short pulse usage of Flagyl is used to actually kill off existing bacteria.

If all goes well the ideal regimen plan I hope to follow is:

I would like to start 200mg doxycycline immediately.  I am writing to you now to request that you consider allowing me to take the antibiotics regimen, and follow the concurrent combination, instead of cycling.  I only have 1 chance to do it right the first time.  I do not want to create antibiotic resistance unnecessarily.

I am going to get the blood work done as planned later this month and then make an appointment to further discuss this treatment plan in person with you.

Dr. David Wheldoni [9] in the United Kingdom is the developer of this specific protocol.  If you have any concerns or questions with the concurrent use of the antibiotic’s or anything else with the regimen I would be glad to facilitate arranging correspondence or teleconference with him.