Clinical outcomes. Here is a summary of the clinical outcome of treatment on the ten patients seen in my laboratory, with established progressive MSi [1] (or progressive neurological illness with MS-like features.) The diagnosis of MS was made at consultant neurologist level.
10 patients were seen and received treatment and were followed up.
In 7 of these progression of the disease was halted.
In all 7 there was some resolution of symptoms.
In all 7 resolution continues.
6 of these 7 patients had cognitive deficits; these were reversed in all 6.
In 3 of the 10 patients progression continued despite 6M treatment.
In 1 of these patients there was little doubt over compliance with medication.
In 2 of these patients compliance with medication was doubtful.
Acute relapse was seen in no patient.
It is a very small number. It includes only those patients seen and followed up on at least three occasions by myself, so does not include self-reporting or anecdotal cases. (It should be borne in mind that the natural history of progressive disease is towards deterioration: although there may be plateaux of stability, the likelihood of a spontaneous global remission is very slim.) David
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D W - [Myalgia and hypertensioni [2] (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazolei [3]i [3]. No medication now; just supplementsi [4]i [4] and IR sauna. Morning BP typically 105/75]
Links:
[1] http://www.cpnhelp.org/taxonomy/term/6
[2] http://www.cpnhelp.org/chlamydia_pneumoniae/ca_0
[3] http://www.cpnhelp.org/taxonomy/term/44
[4] http://www.cpnhelp.org/taxonomy/term/63