Development of antibiotic resistance in Chlamydia pneumoniae

I'm quite frequently asked whether the development of antimicrobial resistance in C. pneumoniae is likely, particularly when starting with one antibiotic or when adding metronidazolei [1] intermittently. To be honest I think the emergence of antibiotic resistance is unlikely, given that the organism in not actively replicating while in the cryptic formi [2]. I've put a new page on my website which discusses this: http://www.davidwheldon.co.uk/resistance.html [3] Do forward comments and criticisms.

(Editor's note: I've attached this post to the Handbook as-is so that readers may see Dr. Wheldon's article directly on his site through the provided link as well as the discussion here at www.cpnhelp.org [4] . That way readers will have access to the most up-to-date version should he edit it on his site. Jim K) 

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D W - [Myalgia and hypertensioni [5] (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazolei [1]. No medication now; just supplementsi [6]i [6] and IR sauna. Morning BP typically 105/75]