Help me figure out what is going on-please! I was diagnosed 3 weeks ago with EBVi [3] and CMV. My numbers were very high and dr. put me on Valtrex 3 gm./day, Lysine 3 gm./day and Guna Virus (homeopathic anti-viral). I was ok on the Valtrex until I increased to 2 gms./day. I began to get that flu-like reaction with bad headaches, eyes got drier and burning, IBSi [4] symptoms returned. I backed off to 1500 mg. for the past week. The terrible headache got better but I still feel awful. Could the anti-virals cause a die-off like response? They only suppress the virus right? I still need to get to 3 gms./day and I'm not feeling any better than I did a week ago. Can anyone tell me (in general) how long it might take to get this viral load down?