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Friedman, Yamamoto, Bendinelli: Cpn - Infection and Disease
By AndreasHH
Created 07/10/2008 - 9:36am

  • Cpn-related research: Member-posted

Hi everybody,

this book is a compilation of articles on cpni [1], published in 2004:

http://www.amazon.de/gp/product/0306484870/ref=sib_rdr_dp [2]

Does anybody happen to know this book? Is it still worth reading being 4 years old?

Greez

Andreas

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Male (43), Germany. NACi [3]; Doxyi [4]i [4], Minoi [5], Azi, Roxyi [6]i [6], Metroi [7]i [7] pulses; Vitamin D + B3, Calciumcluconat, Selenium, Enterococcus faecalis, Lactophilus acidophilus + bifidus

I don't know this book and

Submitted by Michele on Thu, 2008-07-10 10:47.

I don't know this book and from reading the blurb I probably would not as is looks to me like a scientific book.  

A book I did read that does not cost as much is 'the Potbelly syndrome' [8] By Russ Farris.   Very well written, easy to understand, good diagrams and pictures.   Written by a sufferer...

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Michèle (UK) GFAi [9]: Wheldon CAPi [10] 1st May 2006. Daily Doxyi [4], Azi MWF, metroi [7] pulse. Zoo keeper for Ella, RRMSi [11], At worse EDSSi [12] 9, 3 months later 7 now 5.5 Wheldon CAP 16th March 2006

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I have that book - its a

Submitted by garcia on Thu, 2008-07-10 12:08.

I have that book - its a good scientific introduction to chlamydia pneumoniae. It relates cpni [1] infection to a whole host of serious chronic illnesses. So it would be a great book for e.g. showing a doc that this is a serious infection.

The downside is that because it is scientific, a lot of the text concerns intricate biological details which are not clinically relevant. So you probably wouldn't get much in the way of take-home information from a treatment point of view.

 

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Hunter: Don't think - experiment

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@ garcia:What does it say

Submitted by AndreasHH on Fri, 2008-07-11 01:16.

@ garcia:

What does it say on vaccines? Is it possible to get an immunization - after successfully having completed the therapy by antibioticsi [13], or maybe even getting clean from cpni [1] by autovaccines (as a therapy itself)?

Greez

Andreas

___________________________________________________________

Male (43), Germany. NACi [3]; Doxyi [4], Minoi [5], Azi, Roxyi [6], Metroi [7] pulses; Vitamin D + B3, Calciumcluconat, Selenium, Enterococcus faecalis, Lactophilus acidophilus + bifidus

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Andreas, there isn't a

Submitted by garcia on Sat, 2008-07-12 12:57.

Andreas, there isn't a commercial human vaccine available at this point in time, so its not possible to get vaccinated yet. Whether treating a current infection induces immunity from further infection is an interesting issue.

The book has a good article on Cpni [1] Vaccines. On the subject of conferring immunity the authors state: "studies in an experimental model of infection with Ctr indicate a short-lived immunity after natural infection."

There are some major issues to be overcome if a vaccine is to be developed though. One issue is that the same antigens (e.g. Hsp60 & OMP-2) can both lead to increased protection or increased susceptibility depending on the vaccine adjuvant used (some adjuvants encourage a Th2 response which leads to increased susceptibility).

The authors state that "A major challenge here is to produce a strong Th1 response conferring protection without immunopathology."

They also go on to say that: "However, immunity after a natural C. Pnumoniae infection is not completely protective."

On balance it seems then that infection will confer some immunity to the host, but that this is by no means perfect.

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Hunter: Don't think - experiment

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Source URL (retrieved on 12/01/2008 - 5:19pm): http://www.cpnhelp.org/friedman_yamamoto_bendine

Links:
[1] http://www.cpnhelp.org/glossary/term/167
[2] http://www.amazon.de/gp/product/0306484870/ref=sib_rdr_dp
[3] http://www.cpnhelp.org/chlamydia_pneumoniae/supp
[4] http://www.cpnhelp.org/taxonomy/term/39
[5] http://www.cpnhelp.org/taxonomy/term/42
[6] http://www.cpnhelp.org/taxonomy/term/40
[7] http://www.cpnhelp.org/taxonomy/term/44
[8] http://www.amazon.co.uk/s/ref=nb_ss_ce/202-3121992-3032658?url=search-alias=stripbooks&field-keywords=potbelly syndrome&x=0&y=0
[9] http://www.cpnhelp.org/glossary/term/162
[10] http://www.cpnhelp.org/glossary/term/168
[11] http://www.cpnhelp.org/glossary/term/184
[12] http://www.cpnhelp.org/glossary/term/171
[13] http://www.cpnhelp.org/taxonomy/term/38