It is true for most of us, but there have been some people who had little or no rection to NACi [1] but blood tests results were still positive for Cpni [2]. A lot depends on the current status of the infection in your body. If it is not very active at the moment there may be few EBs foating around, as NAC only kills EBs this could results in no reactions.

As far as I know you should not have reactions to NAC if you don't have Cpn.  

Michèle (UK) GFAi [3]: Wheldon CAPi [4] 1st May 2006. Daily Doxyi [5], Azi MWF, metroi [6] pulse. Zoo keeper for Ella, RRMSi [7], At worse EDSSi [8] 9, 3 months later 7 now 5.5 Wheldon CAP 16th March 2006

___________________________________________________________

Michèle (UK) GFAi [3]: Wheldon CAPi [4] 1st May 2006. Daily Doxyi [5], Azi MWF, metroi [6] pulse. Zoo keeper for Ella, RRMSi [7], At worse EDSSi [8] 9, 3 months later 7 now 5.5 Wheldon CAP 16th March 2006

Taking NACi [1] is like the 'poor man's test' for cpni [2]. Most people have some sort of reaction to taking if they have cpn. It might be as slight as runny nose and sinus drainage, to feeling pressure behind the eyes, to ear pressure or tinnitusi [9], all the way up to feeling you're about to come down with the flu: fluctuating body temperature, fever, aching mucscles and joints, lethargy, chest tightness. Michele is right; while NAC is helpful to the liver, you should have no reaction to it if your body is healthy and cpn-free. And that's regardless of whether you take a small or large dose; a larger dose won't give you a 'false' positive for cpn if you don't have cpn.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

___________________________________________________________

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

The only other reaction that NACi [1] produces is in mercury toxic people where it moves mercury around and causes brain reactions ("brain fog"). However this would only occur in people who have a large amount of free mercury floating about - i.e. people who have been chelating recently.

Apart from that we know of no other pathogens which would react sigificantly to NAC other than chlamydiae.

CFSi [10]. Started CAPi [4] 03-07. Currently: Roxi 600mg + Doxyi [5] 200mg . Tinii [11] pulses 1000mg. Sauna QOD. D 8000IU. Niacini [12] 3 x 500mg. Mel 3mg.

___________________________________________________________
Hunter: Don't think - experiment

 Like2know - Since You like2know -

You asked "Also does anyone know if taking NACi [1] at higher doses will cause a reaction even if one does not have CPNi [2]?" 

The long answer to your question from my perspective is that it's scientifically unknown and at best unclear. 

Taking NAC is in no way a scientifically validated method to determine if you have CPN.  Positive reference labs (which are notoriously inaccurate in re to testing Sensitivity - false negatives) for CPN are the only scientifically validated way to determine.

NAC at lower and higher doses initially may be rebuilding depleted stores of glutathione.  Glutathione is a key detox mechanism of the body and rebuilding glutathione stores may cause a detox like reaction that could be similar to NAC flu. 

On the other hand, the reaction could be NAC acting on the EB's of CPN and the NAC flu reaction could be due to dying EB's.   It's impossible at this time to know which reaction is which.

Dr. Stratton reported in his CPN Patent that you would need a substance to dissolve the disulphide bonds of the EB form of CPN.  NAC is such a substance.  It should dissolve the disulphide bonds of the EB's but I don't believe that Dr. Stratton has clinically verified in his lab, NAC specifically as active against CPN EB life forms.

Perhaps Dr. Strattons' new CPN lab can come up with a scientific way to validate NAC as the Poor Man's test for CPN.

To me - in the absence of positive clinical reference labs for CPN, the diagnosis must be made empirically based on other signs and symptoms of the patient and their correlation to latent CPN infection.   Also, there is very little harm/downside to an empiric trial of antibioticsi [13] compared to most other known autoimmune disease treatments.

I personally have resigned myself to the fact that I may never know exactly which combination of cell wall deficient pathogens have invaded my husband's body but an empiric based trial of antibiotics has worked wonders for him so far.

^{Daisy - Husband on CAPi [4] 5/07.   Roxithromycin, Minocycline, Rifampin, Bactrim DS, Mepron, Prednisone, Novantrone, Doxyi [5], Azithromycin, Flagyli [6], Diflucan}

___________________________________________________________

Daisy - Husband on CAPi [4] 5/07.  "When Going Thru Hell, Just Keep Going", Winston Churchill

Thanks Daisy for your well reasoned response.  I am going to bookmark it for the next time I need to give someone the long answer to the NACi [1] question.

Louise USA.CFSi [10].CPn Positive.BbPositive.WheldonCAP6/24/07.NAC,Doxyi [5],Roxi, Tinidazole Pulses. VitD-3,4000IU. Intermittent Cholestyramine 1-2 packets atbedtimewithpulses&asneeded forporphoria&endotoxinsi [14]. 

___________________________________________________________

Louise  CFSi [10], CPN+/Bb+,Wheldon CAPi [4] 6/07, Cholestyramine 1-2 pks @ HS for Porphyriai [15] & Endotoxinsi [14] PRN, Doxyi [5] 200daily, Roxi 300BID, Tini500BIDx14day pulses,VitD3-10,000IU, Iodoral 25mg, {S.O.D.3/QD[KAL Brand], Pyruvate 3.75G, SAM-e For Energy Support

Me, too! Daisy, that is a beautifully written and very clear response to a common question - and a very important question. Thanks.

 

Rica PPMSi [16] EDSSi [8] 6.7 at beginning - now 2. Began CAPi [4] Sept, 2004 with Rifampin 150 mg 2xd, Doxyi [5] 100 mg 2xd, added regular pulses Jan 2005. Jan 2006 switched to Doxy, Azith, cont. flagyli [6] total 51 pulses NC USA

___________________________________________________________

 

Rica PPMSi [16] EDSSi [8] 6.7 at beginning - now 2. Began CAPi [4] Sept, 2004 with Rifampin 150 mg 2xd, Doxyi [5] 100 mg 2xd, added regular pulses Jan 2005. Jan 2006 switched to Doxy, Azith, cont. flagyli [6] total 55 pulses LDNi [17] Rifampin 8/08 again NC USA

like2now      

Using NACi [1] as an empirical test isn't scientifically proven but has been clinically shown to be an effective way of determining whether one has a Cpni [2] infection based on their response.  Others who have responded to you have described some fairly light to mild reactions to it; however, there are cases where the reaction is MUCH more obvious and defined.  So far, myself and maybe 2 others I've seen discuss it here have had a more vigorous reaction.

Consequently, it you're taking it for the first time, start slow, do NOT rush into it unless you are prepared to deal with the worst cases scenario that can result.  I wasn't prepared for it so just sharing some advice I could have used 2+ years ago.   Start slow until you know how you'll respond to it.

all my best

John

RRMSi [7]/EDSSi [8] was 4.5, was 4.???, now 5 on Wheldon Protocol (nac, doxycycline, azithromycin, metronidazolei [6]) since 04/12/2006. Added Rifampin 2x150mg/daily on 08/19/2007. Added INHi [19] 300mg/daily on 03/17/2008 Stop

___________________________________________________________

all my best

John

RRMSi [7]/EDSSi [8] was 4.5, 5, now 6 on Wheldon Protocol (naci [1], doxycycline, azithromycin, metronidazolei [6]) since 04/12/2006. Added Rifampin 2x150mg/daily 08/19/2007. Added INHi [19] 300mg/daily 03/17/2008 stopped 05/08