The article above discusses Vitamin Di [1] binding to Heat Shock Proteins, and I didn't know much about this myself, so for anyone interested, the wiki on Heat Shock Proteins gives some good info on HSPs:

Heat shock protein [8]

Click on the link for HSP 70 toward the bottom of the wiki page for specific information on it...

On Combined Antibiotic Protocol for Cpni [9] in Rosaceai [4] 01/06 - 07/07, On Vit D3 + NACi [6] since 07/07 and daily FIR Sauna since 08/07

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Treatment for Rosaceai [4]

• CAPi [5]:  01/06 - 07/07
• High-Dose Vit D3, NACi [6] & FIRi [7] Sauna Only:  07/07 - 11/08
• Intermittent CAP, High-Dose Vit D3:  11/08 - Present

  Hi Red- Haven't gotten through the article yet, but it looks to be a good one. Scanning the authors I found this one of related interest:

Ann N Y Acad Sci. 2007 Nov;1117:94-105. Epub 2007 Jul 26.Click here to read Links

    Vitamin Di [1] in defense of the human immunei [2] response.

    Adams JS, Liu PT, Chun R, Modlin RL, Hewison M.

    Division of Endocrinology, Diabetes and Metabolism, Burns and Allen Research Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Room B-131, Los Angeles, CA 90048, USA. adamsj@cshs.org [10]

    Defensin is a generic name reserved for an endogenously synthesized antimicrobial agent. The purpose of this review is to describe a series of discoveries that led to the proposal that 25-hydroxylated metabolites of vitamin D are key, intracellulari [11] regulators of the synthesis and action of naturally occurring defensin molecules against bacterial antigens. The discussion will (1) highlight the basic elements of human immune response that is responsive to vitamin D, (2) recount work relevant to the extrarenal expression of the vitamin D-1-hydroxlase (CYP27b1) in the macrophage as an initiator of the innate immune response, and (3) describe recent work on the relevance of the vitamin D intracrine-autocrine-paracrine system in a model of a common and devastating human disease, tuberculosis.

 Full article pdf link.

http://www.annalsnyas.org/cgi/rapidpdf/annals.1402.036v1

CAPi [5] for Cpni [9] 11/04. Dx: 25yrs CFSi [12] & FMSi [13]. Protocol: 200mg Doxyi [14], 300mg Roxithromycin, Tinii [15] 1000mg/day pulses; Vit D1000 units, Iodoral 50mg, T4 & T3

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CAPi [5] for Cpni [9] 11/04. Dx: 25yrs CFSi [12] & FMSi [13]. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii [15] 1000mg/day pulses; Vit D2000 units, T4 & T3

Great article, Jim.  Thanks!  

Great Sunday morning, coffee-time ready for a nerd like me. 

On Combined Antibiotic Protocol for Cpn in Rosaceai [4] 01/06 - 07/07, On Vit D3 + NACi [6] since 07/07 and daily FIRi [7] Sauna since 08/07

___________________________________________________________

Treatment for Rosaceai [4]

• CAPi [5]:  01/06 - 07/07
• High-Dose Vit D3, NACi [6] & FIRi [7] Sauna Only:  07/07 - 11/08
• Intermittent CAP, High-Dose Vit D3:  11/08 - Present

Red,

I so appreciate your presence at this site!  You always post some of the best research !  

^{Daisy - Husband on CAPi [5] 5/07.   Roxyi [17], Diflucan, Rifampin, Bactrim DS, Mepron 4-6, Prednisone, Novantrone, Doxyi [14], Azithromycin, Flagyli [18], Minoi [19]}

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Daisy - Husband on CAPi [5] 5/07.  "When Going Thru Hell, Just Keep Going", Winston Churchill

Daisy- Agreed! It's nerds like Red that help us understand more of what we are dealing with here, and of the resources we need to, as Dr. Powell says, "Make yourself a bad host!" 

CAPi [5] for Cpni [9] 11/04. Dx: 25yrs CFSi [12] & FMSi [13]. Protocol: 200mg Doxyi [14], 300mg Roxithromycin, Tinii [15] 1000mg/day pulses; Vit D1000 units, Iodoral 50mg, T4 & T3

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CAPi [5] for Cpni [9] 11/04. Dx: 25yrs CFSi [12] & FMSi [13]. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii [15] 1000mg/day pulses; Vit D2000 units, T4 & T3

Dan,  Thanks so much for this.  I have to admit, I was too tired to try to understand the really nerdy bits of the text, so I scanned for the tidbits of "meat" in it.  Very cool theories on the history of D and the genetic alterations/adaptations~geography and complexion.  Thanks too for the link on HSPs---lots of fodder for pondering there.

Joyce~caregiver-advocate in Dallas for Steve J (SPMSi [20]).  CAPi [5] since August 06, Cpni [9], Mpn, B. burgdorferi, systemic candidiasis, EBVi [21], CMV & other herpes family viral infectionsi [22], elevated heavy metals, gluten+casein sensitivity. 

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Joyce~caregiver-advocate in Dallas for Steve J (SPMSi [20]).  CAPi [5] since August 06, Cpni [9], Mpn, B. burgdorferi, systemic candidiasis, EBVi [21], CMV & other herpes family viral infectionsi [22], elevated heavy metals, gluten+casein sensitivity. 

Hi Red, I can't post a new forum topic for this because of the site change, so I hope you don't mind that I added to your excellent thread.

Those with low vitamin D twice as likely to die [23]

The title of the article is a sure attention grabber.

Here's one more:

Vitamin D may prevent heart attacks in men [24]

Study: Those with lower levels were 2 1/2 times more likely to have attack

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Corinna | GFAi [25]. Wheldon Protocol: 4–8/08. Can't kill the yeast.

Hi Corinna,

Thanks. Interesting (and scary) studies!

Here's the abstract for the first study for anyone interested, btw:

Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels With All-Cause and Cardiovascular Mortality [26]

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Treatment for Rosaceai [4]

• CAPi [5]:  01/06 - 07/07
• High-Dose Vit D3, NACi [6] & FIRi [7] Sauna Only:  07/07 - 11/08
• Intermittent CAP, High-Dose Vit D3:  11/08 - Present