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My Doctor had a question.
By Todybear
Created 04/30/2008 - 6:34pm

At my appointment today, my doctor was telling me that Doxyi [1] and Azith should not cause any problems and Flagyli [2] only makes a few people feel "funny" but that is very rare. I explained the concept of die off effects to him and he looked at me with a very puzzled look on his face. He said that if it is true that people on the abxi [3] feel very lousy on Flagyl, why doesn't everyone feel lousy on it as most people have Cpni [4] in varying degress. He wondered why people get these die off effects on this abxi [5] and not his patients that he prescribes Flagyl to for other reasons. I unfortunately could not answer him, can anyone answer that?

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SPMSi [6]i [6]< Supplementsi [7]i [7] & NACi [8], Doxyi [1] 200 mg, Azith 250 mg 3X/wk, most suppliments, currently Flagyli [2] 1500 mg x 4 days once per month

 Tody- That most people

Submitted by Jim K on Wed, 2008-04-30 18:57.

 Tody- That most people don't have reactions to abxi [3] or flagyli [2] is exactly the point: you only have strong reactions to these meds if you are killing significant enough amounts of Cpni [4] so as to release significant amounts of porphyrins and endotoxinsi [9].

In other words, the fact that most people don't respond negatively to antibiotics essentially confirms that they do not have significant amount of Cpn in their body. They may have titers for exposure, but their immunei [10] system has been able to control it adequately. 

The difference for those of us with Cpn and related disease symptoms (MS, ME, CFSi [11], FMSi [12], Sjogrens, etc, etc) is that our system has not been able to adequately control the Cpn so that the bacterial loadi [13] is much higher and has invaded more tissues.  So when we take these agents we are killing more Cpn and also probably a number of host cells as well, all of which causes us a much stronger reaction.

CAPi [14] for Cpn 11/04. Dx: 25yrs CFS & FMS. Protocol: 200mg Doxyi [1], 300mg Roxithromycin, Tinii [15] 1000mg/day pulses; Vit D1000 units, Iodoral 50mg, T4 & T3

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CAPi [14] for Cpni [4] 11/04. Dx: 25yrs CFSi [11] & FMSi [12]. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii [15] 1000mg/day pulses; Vit D2000 units, T4 & T3

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ya, what Jim said, lol I was [16]

Submitted by ruthless1 on Wed, 2008-04-30 19:05.

ya, what Jim said, lol

I was also wondering, was he meaning treatment with one abxi [3] at a time.  Then there would be very few problems. 

If you look at the list of "reactions" from the pharmacy that occur rarely on the abxi [5] we take, some of them look very similar to the reactions we have resulting from porphyriai [17] & toxins.  Coincidence!! imhoi [18], I think not.

CFIDSi [19]/ME 26yrs, FMSi [12], IBSi [20], EBVi [21], CMV, Cpni [4], chronic insomnia, Lymes, HME, Natural HRT peri-M, NACi [8] 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, Pulse#9 750mg 5.5 day, 4-25-8

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CFIDSi [19]/ME 32 yrs, FMSi [12], IBSi [20], EBVi [21], CMV, Cpni [4], H1, chronic insomnia, Lymes, HME, Natural HRT peri-M, NAC 3 gm, Full CAP 6-2-08, all supplementsi [7] +Sea Kelp, Chitosan Pulse 16 1-4-09 1gm Flagyli [2]/day-3 days

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Wow Jim, good answer. I wish

Submitted by Todybear on Wed, 2008-04-30 19:06.

Wow Jim, good answer. I wish I had that information earlier today. Makes perfect sense though cause if a Cpni [4] load wasn't causing problems, we wouldn't be sick in the first place.

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SPMSi [6]< Supplementsi [7] & NACi [8], Doxyi [1] 200 mg, Azith 250 mg 3X/wk, most suppliments, currently Flagyli [2] 1500 mg x 4 days once per month

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Indeed Ruthless. Many times

Submitted by Todybear on Wed, 2008-04-30 19:11.

Indeed Ruthless. Many times when I go on a drug therapy, I seem to get that 1 in a million reaction that the doctor finds in the small print in his medical book. They always tell me it is because I am very drug sensitive and the reaction is very rare. Could be cause I have die off and start to feel effects.

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SPMSi [6]< Supplementsi [7] & NACi [8], Doxyi [1] 200 mg, Azith 250 mg 3X/wk, most suppliments, currently Flagyli [2] 1500 mg x 4 days once per month

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Todybear, Tell your doctor

Submitted by MacKintosh on Thu, 2008-05-01 02:23.
Todybear, Tell your doctor the reason people who are on monotherapy don't have these strong reactions is because the three abxi [3] work synergistically to kill off the organism. Any one of them by itself won't show much reaction in most people, unless they have a really high bacterial loadi [13] (and then sheer numbers will just win out and show some reaction anyway). And, those people who have reactions to just one are usually written off as having 'bad side effects' from the meds. Put two or more of them (abxi [5]) together and you suddenly see more serious die-off.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems.  Mohandas Gandhi

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The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

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You might want to take a

Submitted by garcia on Thu, 2008-05-01 07:07.

You might want to take a look at this page:

Metronidazole Patient Database

What they call "Side effects" we call (intended) die-off effects. 

There are quite a lot of people who react strongly to flagyl out there. Presumably many of them have an undiagnosed chlamydial infection (or some similar pathogen). 

CFSi [11]. Started CAPi [14] 03-07. Currently: Roxi 600mg + INHi [22] 600mg + Tinii [15] 1000mg. 10 Pulses done. Sauna every other day. D 7200IU

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Hunter: Don't think - experiment

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I agree with Garcia (and Jim

Submitted by Michèle on Thu, 2008-05-01 07:49.

I agree with Garcia (and Jim of course). I was making that point in the FAQs page... What people often call side effects of drugs, are due to  an unrecognised Cpni [4] infection, exactly because Cpn is quite common this may be a 'side effect' that is often noted by patients and eventually gets recognised and listed in the advice sheet.

Michèle (UK) GFAi [23]: Wheldon CAPi [14] 1st May 2006. Daily Doxyi [1], Azi MWF, metroi [2] pulse. Zoo keeper for Ella, RRMSi [24], At worse EDSSi [25] 9, 3 months later 7 now 5.5 Wheldon CAP 16th March 2006

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Michèle (UK) GFAi [23]: Wheldon CAPi [14] 1st May 2006. Daily Doxyi [1], Azi MWF, metroi [2] pulse. Zoo keeper for Ella, RRMSi [24], At worse EDSSi [25] 9, 3 months later 7 now 6.5 Wheldon CAP 16th March 2006

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I can vouch for this.

Submitted by Andesine on Thu, 2008-05-01 09:24.

I can vouch for this. Halfway through week 2 of Doxyi [1] on its own, and I've developed a twitch. I've had a few odd stabbing pains, some bronchial clearance and some headaches. 

Next week I add Zithi [26]. Watch this space. 

Berkshire, UK. Diagnosed RRMSi [24] Feb 4th 2008.

NACi [8] 2400mg. All supplementsi [7]. Doxy 200mg.
No GP/Neuroi [27] support. Self medicating with help from David Wheldoni [28].
Started CAPi [14] 20th April 2008.

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Berkshire, UK. Diagnosed RRMSi [24] Feb 4th 2008.

NACi [8] 2400mg. All supps. Doxyi [1] 200mg. Zithi [26] 250mg. Metroi [2] 400mg.
No GP/Neuroi [27] support. Self medicating with help from David Wheldoni [28].
Started CAPi [14] 20th April 2008. First pulse June 2008

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It amazes me that a dr

Submitted by clammed_up on Thu, 2008-05-01 13:40.

It amazes me that a dr wouldnt understand the concept of die off. Im sorry that you have to educate him. What do they learn in school anway.

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CPNi [4] pcri [29] and antibody positive , treating MSi [30], CFSi [11], TMJ, trigeminal neuralgia, IBSi [20] neutropenia, pus found in facial bone, Doxyi [1] 100x2,Doxy 200x2 zithro 250x1 alternate days. Metroi [2] pulses each month.

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