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Minai - Agree with Sarah.  No known drug/drug interaction between these antibioticsi [12].   My husband took 7 days of Levaquin while on Doxyi [1] and Azith for a UTIi [13] - zero problems.

Daisy  - Husband on CAPi [4] 5/07.  Minoi [14], Roxy, Diflucan round two 1-31, Rifampin, Bactrim DS,  Prednisone, Novantrone, Doxy, Azith

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Daisy - Husband on CAPi [4] 5/07.  "When Going Thru Hell, Just Keep Going", Winston Churchill

Thanks for the responses. So, good to know that I don't have to stop Doxi and Roxi. My husband just came home and demanded I take the Levaquin because he had cellulitis in Ranger school--no fun!. And, his father was recently hospitalized for it, after their new kitten scratched his chest. But I am afraid to take it, since I am afraid it will be worse than an 8 day pulse of Tinii [15]/Flagyli [16]. I did a search on this site and found that others have reacted strongly to it (Raven, Jeanne, and others). And, lifeontheice (Barbara) posted that she thinks it's very effective in treating Cpni [17]. Thanks for sharing your husband's experience, Daisy. It does give me some courage to try it.

--Minai

p.s. to Sarah: I thought of you yesterday, when they served us champagne for brunch at the Officer's club.

Minai..  I am going to disagree with the others... Levoquin is a very powerful antibiotic (that's what they created it to be-- an all encompassing antibiotic).  I personally will not take another fluroquinoline -- even for a short period of time as they can do damage to the tendons as well as other problems.  It is your decision but there are other antibiotics that could be used. Since it is stated that "it is very effective in treating CPNi [17]" -- adding anything to the mix could contribute to additional die-off.

My husband has been experiencing subcutaneous cellulitus (a staph infection that won't go away)  He was taking 2 tabs of  DS SMP/TMZ (800 mg of Sulfameth/160 mg of Trimethoprim) which originally (this is his 3rd episode) made it go away.  It has come back and   he recently went to an infectious disease specialist .  He is now on that drug 4 tabs per day, times a day PLUS 300 mg of Rifampin 2 x's per day.

DS TMP/SMZ is double-strength Bactrim... perhaps if you requested your doc would prescribe that -- even with Bactrim, though, you may experience additional die-off.

Just my opinion -- I've read too many negatives on Levaquin as well as my personal experience.  You don't have to stop the other ABXi [12], but  I personally don't believe you will not "notice" adding anothere one ... just playing Devil's Advocate here.....

I hope all works out for you! 

Jeanneroz ~CPN 4/2007; HHV6, EBVi [18], CFIDSi [19]/FM- diagnosed: 6/07; IBSi [20], prior kidney infectionsi [21], food allergies, hypothyroid (RAI for Graves in 1998), Adrenal issues; prior bronchitis/sinus problemsi [22]. 200 mg/doxyi [1] daily & 250 mg AZITH M/W/F, supplmnts

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JeanneRoz~CPNi [17] diagnosed & started protocol 4/2007, also HHV6, EBVi [18]. CFIDSi [19]/FM diagnosed: 6/07; 100mg/doxyi [1]/BID ~ 250 mg AZITH M/W/F ~1st Tinii [15] pulse 4/17/08- 1 250 mg. tab for 2 days. Pulse 5: 9/28/08, 250 mg TINI BID, 3 days. Sup

hmmm, reading above I wonder if this is one of those times where the MSer reactions are different/more tolerable than for those with ME??

CFIDSi [19]/ME 25yrs, FMSi [23], IBSi [20], EBVi [18], Cpni [17], (insomnia - melatonini [24], GABA, tarazadone, triazolam, novocycloprine, allergy formula, 3 gm tryptophan), Natural HRT peri-M, NACi [3] 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, 2-6-08 6th pulse 1 X 375 mg 5day

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CFIDSi [19]/ME 32 yrs, FMSi [23], IBSi [20], EBVi [18], CMV, Cpni [17], H1, chronic insomnia, Lymes, HME, Natural HRT peri-M, NAC 3 gm, Full CAP 6-2-08, all supplementsi [25] +Sea Kelp, Chitosan Pulse 16 1-4-09 1gm Flagyli [16]/day-3 days

Ruth, actually, I thought of that after I posted.... but I still believe other antibioticsi [12] are "healthier/better" for the body and that, too, is just my opinion :)

 

Jeanneroz ~CPNi [17] 4/2007; HHV6, EBVi [18], CFIDSi [19]/FM- diagnosed: 6/07; IBSi [20], prior kidney infectionsi [21], food allergies, hypothyroid (RAI for Graves in 1998), Adrenal issues; prior bronchitis/sinus problemsi [22]. 200 mg/doxyi [1] daily & 250 mg AZITH M/W/F, supplmnts

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JeanneRoz~CPNi [17] diagnosed & started protocol 4/2007, also HHV6, EBVi [18]. CFIDSi [19]/FM diagnosed: 6/07; 100mg/doxyi [1]/BID ~ 250 mg AZITH M/W/F ~1st Tinii [15] pulse 4/17/08- 1 250 mg. tab for 2 days. Pulse 5: 9/28/08, 250 mg TINI BID, 3 days. Sup

Hi sunshine,

you are right, a person should question these things & it is great you shared your experience & knowledge! 

We take what we take as the side affects are minimal compared to other abxi [12].

CFIDSi [19]/ME 25yrs, FMSi [23], IBSi [20], EBVi [18], Cpni [17], (insomnia - melatonini [24], GABA, tarazadone, triazolam, novocycloprine, allergy formula, 3 gm tryptophan), Natural HRT peri-M, NACi [3] 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, 2-6-08 6th pulse 1 X 375 mg 5day

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CFIDSi [19]/ME 32 yrs, FMSi [23], IBSi [20], EBVi [18], CMV, Cpni [17], H1, chronic insomnia, Lymes, HME, Natural HRT peri-M, NAC 3 gm, Full CAP 6-2-08, all supplementsi [25] +Sea Kelp, Chitosan Pulse 16 1-4-09 1gm Flagyli [16]/day-3 days

You've given me some very helpful advice, Jeanne. Not just for me, but for my husband. He's been suffering from a staph infection, on his head, for months. If/when he finally decides to go in to Walter Reed, he'll at least know what to ask for. The foot doctor did start to refer me to an infectious disease doctor. That is, until I told him that I would not stop taking Doxyi [1] or Roxi. I even asked him about Flagyli [16]/Tinii [15], thinking that if I start pulsing, again, it might treat it. I think what I will do is call the foot doctor and ask for the referral. Maybe she'll be willing to prescribe Bactrim, without making me stop the other ABXi [12]. If not, I have an appt with my Lyme GP, Friday. He might prescribe it, if I ask. Although, he hasn't been very communicate or helpful, lately. Especially, with the adrenal symptoms that I continue to experience. I just don't like the idea of anything that might harm tendons, especially in my gimpy left leg and foot, same side this toe is on. And, certainly don't think that I can handle much more die-off due to the adrenal symptoms, either. Thanks, again!  --Minai

RRMSi [2], diagnosed 2/04. NACi [3] 4/06. Started Wheldon/Stratton regime 8/30/06. Doxycycline, 8/06, Azith, 10/06. Switched to Roxithromycin 11/06. Psuedo relapse/die-off with hospitalization 1/07. Gad-enhanced MRI of brain and spine shows NO NEW DISEASE ACTIVITY Restarted CAPi [4] with NAC and Doxy 2/07. LDNi [5] 4/07. Stopped NAC, started Roxi, again 5/07. Now on full doses of Doxy and Roxi. NAC, again, 7/07. 1st Tinidazole Pulse, 8/11/07. USA

 Minai- okay, I'll weigh in with another take, not that you need it! Most of the tendon problems on Levaquin have come from much longer use than 8 days. You can do a scan of the internet on this but that's what I have seen. I'd do the 8 days, cut out either the doxyi [1] or roxyi [10] if you get uncomfortable die-off, and get the cellulitis taken care of. Git 'er done!

CAPi [4] for Cpni [17] 11/04. Dx: 25yrs CFSi [27] & FMSi [23]. Protocol: 200mg Doxy, 500mg MWF Azith, Tinii [15] 1000mg/day pulses; Vit D1000 units, INHi [28] 150mg, Magnascent Iodine 20 drps/day, T4 & T3

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CAPi [4] for Cpni [17] 11/04. Dx: 25yrs CFSi [27] & FMSi [23]. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii [15] 1000mg/day pulses; Vit D2000 units, T4 & T3

I will never take levaquin again.  I still have tendon pain only from a seven day course.

In my opinion it's one of the worst antibioticsi [12] in terms of possible permanent damage out there.

If you do take it make sure you quadruple your magnesium as some docs believe this is why the damge occurs in the tendons.

Yikes! Never mind. Only 7 days? Willikers! 

CAPi [4] for Cpni [17] 11/04. Dx: 25yrs CFSi [27] & FMSi [23]. Protocol: 200mg Doxyi [1], 500mg MWF Azith, Tinii [15] 1000mg/day pulses; Vit D1000 units, INHi [28] 150mg, Magnascent Iodine 20 drps/day, T4 & T3

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CAPi [4] for Cpni [17] 11/04. Dx: 25yrs CFSi [27] & FMSi [23]. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii [15] 1000mg/day pulses; Vit D2000 units, T4 & T3

Jim.. my right knee problem began on day 5 of 500 mg's. It swelled up larger than a baseball. That was in March of '07.  I am still having problems walking on that leg (well, walking in general...)  It is very weak, my knee feels "blown" and I can't put my weight on it. 

Jeanneroz ~CPNi [17] 4/2007; HHV6, EBVi [18], CFIDSi [19]/FM- diagnosed: 6/07; IBSi [20], prior kidney infectionsi [21], food allergies, hypothyroid (RAI for Graves in 1998), Adrenal issues; prior bronchitis/sinus problemsi [22]. 200 mg/doxyi [1] daily & 250 mg AZITH M/W/F, supplmnts

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JeanneRoz~CPNi [17] diagnosed & started protocol 4/2007, also HHV6, EBVi [18]. CFIDSi [19]/FM diagnosed: 6/07; 100mg/doxyi [1]/BID ~ 250 mg AZITH M/W/F ~1st Tinii [15] pulse 4/17/08- 1 250 mg. tab for 2 days. Pulse 5: 9/28/08, 250 mg TINI BID, 3 days. Sup

 I remember when I took it last year after sinus surgery on the third day I cracked my knuckles out of habit.  My knuckles and fingers had purple striations(sp) all over them.  That was my first clue.  Then the insides of my legs right above the knee had the strangest feel to them like they were being pulled loose with every step.  If you feel the inside of your leg it has a huge band of tendons connecting the knee.  I still didn't grab a clue.  the last draw was when I quickly took off to run up some stairs, my left achilles(sp) blew up.

I then researched Levaquin side effects and said 'oh boy this is going in the trash'  It took me one plus year to get things back in order and I still have a twinge in those areas today.  Very scary

If anyone here has children that are involved in sports..and the doc prescribes them Levaquin, politley say no thanks.  I bet this drug has ruined many athletes without them knowing the cause.

I took ofloxacin, which is the only different isomer of the same medc., double dose for 6 weeks before starting CAPi [4]. And it was the best abxi [12] I have ever had. I got strong reaction to it, but lots of things amazingly improve, some of them more,than now after 2 years on protocol. I also have pain inside my legs, but this is certainly due to cpni [17]. It worsens after pulses, other days is quite ok. And it worsened also after ofloxacin, after which I experienced reactions for months. Then during CAP last year I suddenly got urinary tract infection. Doctor let me select between norfloxacin and trimethoprime/sulfamethoxazole, I choose norfloxacin for 7 days together with CAP. No problem at all, no additional die-off, only little more fatigue for few days. Both drugs I tolerated very well. Prague, The Czech Republic, On Wheldon protocol for Cpn and Mycoplasma since 02/18/2006.

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Prague, The Czech Republic, On Wheldon protocol since 02/18/2006, CFSi [27] and many problems 30 years (cpni [17] and mycoplasma), 3rd year on protocol- doxyi [1], azi, tinii [15] pulses

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Hi Sarah... yes you are right (my lead-in statement should have been different).  I wasn't disagreeing that Levaquin cannot be taken with doxyi [1] and roxi.  What I am disagreeing with is ( and I mean no offense here -- just a reality check, pls) :  some on this site who  have had little to no reaction to the ABXi [12] are wonderful in  supporting  the others; but not having had much reaction you do not truly understand what it is like to HAVE severe die-off, porphyriai [30], etc.   It is easy to tell others to "take the pills, and live your lifes, or take the pills and suffer the fall out, or take the pills the die-off is worth it" when you have no idea what the ordeal is like.  Especially when it incapacitates you totally.  

I have a tendency to weigh on the other side of cautious reminding others, (who do experience symptoms), of the negative repercussions and to think about their choices. Hopefully, my comments are viewed as realistic and not negative.  Someone unexperienced or who doesn't think about it could very easily believe  "oh, this won't make a difference" and then feel terrible and kick themselves afterwards.  So I play the advocate just to have the pause to think about it. 

Each of us, individually,  knows how our bodies are reacting. It would be wonderful if we could just "take these pills and get on with my life",... but for some of us that doesn't happen ......Sooooo, I tend to be on the cautious side.

Thanks for listening   

Jeanneroz ~CPNi [17] 4/2007; HHV6, EBVi [18], CFIDSi [19]/FM- diagnosed: 6/07; IBSi [20], prior kidney infectionsi [21], food allergies, hypothyroid (RAI for Graves in 1998), Adrenal issues; prior bronchitis/sinus problemsi [22]. 200 mg/doxy daily & 250 mg AZITH M/W/F, supplmnts

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JeanneRoz~CPNi [17] diagnosed & started protocol 4/2007, also HHV6, EBVi [18]. CFIDSi [19]/FM diagnosed: 6/07; 100mg/doxyi [1]/BID ~ 250 mg AZITH M/W/F ~1st Tinii [15] pulse 4/17/08- 1 250 mg. tab for 2 days. Pulse 5: 9/28/08, 250 mg TINI BID, 3 days. Sup

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Hey Sunshine.

You have defintely been slammed by the CPni [17] critters & your other viral & bacterial infectionsi [21].  You are on the severe symptom side of ME & slowly clawing your way back to a better life.   Plain & simple, you feel like crap!

It is really great to have reports from all angles, that is for sure.

I have learned from this post that I will not take Levaquin with these red flags because of all the tendon, ligament injuries I have had in all my joints in my little world! LOL.

 

 CFIDS/ME 25yrs, FMSi [23], IBSi [20], EBVi [18], Cpn, (insomnia - melatonini [24], GABA, tarazadone, triazolam, novocycloprine, allergy formula, 3 gm tryptophan), Natural HRT peri-M, NACi [3] 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, 2-6-08 6th pulse 1 X 375 mg 5day

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CFIDSi [19]/ME 32 yrs, FMSi [23], IBSi [20], EBVi [18], CMV, Cpni [17], H1, chronic insomnia, Lymes, HME, Natural HRT peri-M, NAC 3 gm, Full CAP 6-2-08, all supplementsi [25] +Sea Kelp, Chitosan Pulse 16 1-4-09 1gm Flagyli [16]/day-3 days