Cpnhelp.org - Chlamydia Pneumoniae Treatment

Hmmmm, very interesting...Thanks for posting this!

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On Combined Antibiotic Protocol for Cpni in Rosaceai 01/06 - 07/07, On Vit D3 + NACi since 07/07 and daily FIRi Sauna since 08/07

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CAPi for Cpni 11/04. Dx: 25yrs CFSi & FMSi. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii 1000mg/day pulses; Vit D2000 units, T4 & T3

 

Gosh, all those people who are using statins as a treatment for their MSi are maybe doing more for it than they thought.  There's a forum for statins over at ThisisMS.  Guess where I'm going now!.............Sarah

An Itinerary in Light and Shadow

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Go Sarah!

You know, I know I'm probably more than a little biased, but given the evidence of infection with the diseases that some statins seem to help and given that people don't seem to get worse with statin treatment (which you might expect if they just had anti-inflammatory effect), you kind of had to figure some of the statins (not all seem to work) have antimicrobial qualities.

BTW, similar studies suggest that simvastatin, reduces the incidence of Alzheimer's diseasei and Parkinson's disease by almost 50 percent:

Specific Statin Significantly Reduces Alzheimer's And Parkinson's Disease Risk, Study Shows

Unfortunately research on many of the other statin class drugs cloud the findings, but combine the above with research that suggest that some of the statins have a direct effect on Cpni growth:

Effect of Simvastatin, an Established Lipid-Lowering Drug, on Pulmonary Chlamydia pneumoniae Infection in Mice

Effect of pravastatin treatment on Chlamydia pneumoniae infection, inflammation and serum lipids in NIH/S mice

And, from a common sense standpoint (if not a medical one), it all seems pretty clear...

 

 

 

 

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On Combined Antibiotic Protocol for Cpni in Rosaceai 01/06 - 07/07, On Vit D3 + NACi since 07/07 and daily FIRi Sauna since 08/07

To add to the picture, here's a review article saying that, with all the big studies that have been done on statins, nobody has actually proven that they work by lowering LDL cholesterol, and that they might have other mechanisms of action which are responsible for their lowering the death rate (which at least some of them have been pretty definitively proven to do).

I had a look at the full paper. The antimicrobial effects it reports are, by the authors' computation, only present at concentrations about three orders of magnitude above what people normally take. They say some things about there possibly being more accumulation of the drug in the elderly, and such; but one can't get three orders of magnitude out of effects like that.

Normon- One factor might be that the anti-Cpni effect is not based on having a direct antimicrobial effect, rather that it denies cholesteroli to EB'si attempting to invade cells via lipid-rafts and form inclusions. No cholesterol, no inclusions. This is the same way in which the delta-tocotreinols, which also lower LDL, appear to work. So it's effect is more from limiting invasion of new cells and infected cell attrition.

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CAPi for Cpni 11/04. Dx: 25yrs CFSi & FMSi. Currently: 150mg BID Roxithromycin, Doxycycline 100mg BID, Tinii 1000mg/day pulses; Vit D2000 units, T4 & T3