Niacinⁱ - What is it? A B-vitamin (B3) which is both depleted in Cpnⁱ-infection, and which can be used in higher doses as an anti-chlamydidal (may require liver monitoring).

What you want: The regular (flush producing), immediate release type (avoid sustained release and also avoid no flush forms of niacin). 100mg is a typical starting dose, e.g. see this.

Here are some relevant forum threads:

1. Dr Powell's comments on niacin can be found here:
http://www.cpnhelp.org/powell_niacin

Ignore the bit where he says that "Eventually time-released niacin can be used ..." as you want to avoid timed release (see later).

Watch out for Jim's excellent post in that thread in which he posts the following summary:

• "Cpn disturbs niacin metabolism.
• This results in impaired T-cell function, low melatoninⁱ, low serotonin, low tryptophan, low niacin, all of which are problems for us (depression, insomnia, immuneⁱ problems, etc.)
• Niacin also counters endotoxinⁱ reactions (cold hands and feet, low body temperature, etc)
• You have to use regular niacin, which causes a flushing reaction (I get itchy too), and have to ramp up gradually, and you will tolerate higher dosage as you build.
• Gear towards 500-1000 mg per day spread over the day.
• As it can be liver toxic in these larger doses, make sure your liver and CBC blood panels are checked regularly if you are using this supplement in this way."

2. Another good thread which talks aobut dosages amongst other things is: http://www.cpnhelp.org/niacin_how_far_to_go

Norman posts there about his negative results with sustained release. Also in this post Jim says:

"Best not to use the sustained release. In a conversation with Dr. Stratton he noted once that the regular, non-sustained niacin seemed to produce the best affect."

3. Finally Norman has an update on his niacin experiences:
http://www.cpnhelp.org/liver_interlude

where using sustained release niacin resulted in raised liver enzymes requiring a 4-month hiatus from the CAPⁱ.