New research-Abx for back pain

Hi guys, Wasn't sure if anyone had read this. Seems pretty interesting----low back pain caused by infection!!!

Couple of interesting points--see what you think.

-The bacteria thrives in low/no oxygen -Researchers were surprised to find the bacteria in supposedly "sterile" spinal cord disc areas.
-They didn't mention what bacteria they found--just that they think one acquires it by brushing teeth.
-Of course, the researchers think that first herniation occurs and only then the bacteria find a way in...hmmmm.

Here's the article:

A simple antibiotic used to fight gum infections could offer pain relief to people with chronic low back pain.

Up to one in five cases of low back pain might be due to a bacterial infection of a spinal disc that occurs after patients brush teeth, according to some researchers.

Dr Hanne Albert is leading a clinical trial involving 172 patients at the Back Research Centre at the University of Southern Denmark.

She said: "We think that when the patient with a herniated or slipped disc brushes their teeth, bacteria from the mouth get into the bloodstream, travel to the damaged disc where they thrive, and the body reacts to the infection - resulting is low back pain."

The bacteria enter the blood through tiny holes torn in the gums by your toothbrush.

Results from a small pilot study of about 30 people show that seven out of ten patients who had been in pain for many years benefited from an antibiotic widely used to treat a number of bacterial infections, and that a number were pain-free following the treatment.

It is estimated that nearly twothirds of adults in the UK have suffered from back pain and that 2.5 million people have symptoms every day of the year.

Pain in the lower region - the lumbar - is the most common. From there it can spread to the thighs and upper legs.

Many patients find the pain disappears within three months, but up to 50 per cent continue to have pain and disability.

A herniated disc, where pain is caused by disc material bulging and putting pressure on a nerve, is one of the main causes of back and leg pain.

Dr Albert and her colleagues had noticed that many patients with herniated discs found that the leg pain - sciatica - that can go with it disappeared after three to six months.

However, the patients continued to suffer from low back pain - and when they underwent scans, most patients were found to have oedema, or a build-up of fluid, in the bone where the disc had herniated.

Other research has shown that herniated discs contain bacteria which thrives in tissue with no or low oxygen.

"What was puzzling was why this bacteria was occurring in what is a sterile area of the body." says Dr Albert.

When a disc becomes herniated, the material that slips out is surrounded by new blood vessels and repair cells.

As a result, tiny blood vessels grow into the soft centre of the extruded disc tissue. This tissue does not normally have blood vessels and is one of three areas, along with the outer hair and cornea, which are free of oxygen.

Because they have no blood supply, it is not possible for bacteria to travel through the blood into a healthy disc.

The theory is that the new blood vessels that occur after herniation allow bacteria to get into an area, which had been inaccessible.

Dr Albert says: "We know that ten minutes after you brush your teeth, there is a bacteria in your blood. It gets there through tiny holes in gums made by brushing.

"This is exactly the same type of bacteria that has been found in damaged discs.

"We think that bacteria gets into the disc tissue through the bloodstream. The bacteria finds a place without oxygen where there is no competition from other bacteria, so it thrives."

If the theory is right, antibiotics should be able to stop or reduce the pain for many people with low back pain due to previous herniated discs.

In the trial, the 172 patients will get a daily pill for three months.

Here's the link: http://tinyurl.com/yuphnc

Lexy

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"Chance favors the prepared mind." --Louis Pasteur

Husband treating MSii with CAPii

Lexy, Thanks for this.

Lexy, Thanks for this. Having lived through (survived) the clean up period of my back, preceded by my neck and my shoulder, and now my hips and knees, I really have to nod my head in comprehension of the article. Such denial and sometimes dawning realization is happening in the world. One of these days we who have said "Of course!" and lived through "the clearing" will with difficulty try not to say "I told you so" and maybe cheer instead.

 

Rica PPMSi  EDSSi 6.7 at beginning - now 2.  Began CAPi Sept, 2004 with Rifampin 150 mg 2xd, Doxyi 100 mg 2xd, added regular pulses Jan 2005. Jan 2006 switched to Doxy, Azith,  cont. flagyli  total 40 pulses NC USA

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Rica PPMSi EDSSi 6.7 at beginning - now 2. Began CAPi Sept, 2004 with Rifampin 150 mg 2xd, Doxyi 100 mg 2xd, added regular pulses Jan 2005. Jan 2006 switched to Doxy, Azith, cont. flagyli total 52 pulses LDNi Rifampin 8/08 again NC USA

Thanks Lexy,One of the

Thanks Lexy,

One of the first things that got better for me was the low back pain, still troubles me from time to time but so much better than before.   Funnily enough doxycycline is an antibiotic frequently prescribed for gum disease.

 

Michele: Wheldon CAP1st May 2006 for ailments including IBSi, sinusitis, alopeciai, asthmai, peripheral neuropathy. Spokesperson for Ella started Wheldon CAP 16th March 2006 for RRMSi. Sussex UK

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Michèle (UK) GFAi: Wheldon CAPi 1st May 2006. Daily Doxyi, Azi MWF, metroi pulse. Zoo keeper for Ella, RRMSi, At worse EDSSi 9, 3 months later 7 now 5.5 Wheldon CAP 16th March 2006

Sehr interessant, Herr

Sehr interessant, Herr Doktor. Never heard of anything like this. I think back pain is one of the most abundant chronic diseasesi in the US. I wonder if the pilot abxi trial was published. I couldn't find it, but the news article doesn't give you much to search for it with.

I made a 90-second rumage for the previous bacteria detection work(s) mentioned. Came up with one PMID, 15138861.

I also set up a literature alert on "Albert HB", a trick JimK taught me last year. Very useful. Just click that "Save Search" button next to the search blank on pubmed. Pay no money now. There's never any obligation to buy. Pubmed's diligent robots are here to serve you. Just sit back and relax for about 2 years, and viola, they email you when the newly completed paper gets published. It's the ultimate free lunch. Does take a while though.

Lexy, low and behold, there

Lexy, low and behold, there was another related article on Gum Disease affecting the entire body in Monday's Los Angeles Times. Raven

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CAPi since 8-05 for Cpni and Mycoplasma P. for MSi and/or CFSi Also EBVi and HHV6

Whoops, where did the URL

Whoops, where did the URL go? http://tinyurl.com/2dtmy9

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CAPi since 8-05 for Cpni and Mycoplasma P. for MSi and/or CFSi Also EBVi and HHV6

Oh, this is interesting. I

Oh, this is interesting. I have had low back pain for a while. It hasn't improved since starting abxi but I'm still only on azi. I wonder if I could use this as a way to persuade my doc to add doxyi. You think that's the one that does it? I wish they'd mentioned which bacteria and antibiotics they used.

Asthmai, chronic sinusitis/rhinitis, chronic tendonitis, hypothyroid. Jan 9, '08 - started azithromycin 1000mg/week. Mar 13, '08 - increased azi to 250mg/day, added 20mg Benicar daily.

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Asthmai, sinusitis/rhinitis, tendonitis, low back pain, hypothyroid. Started azi 1000mg/week Jan 9, '08. Increased azi to 250mg/day, added 20mg Benicar daily Mar 13, '08. First Flagyli pulse started June 30, '08. Added Doxyi 200mg/day Aug 16.

My problems began with

My problems began with chronic back pain and proliferated from then on. I am so on board with this kind of thinking. I had poor dental care as a child and things branched out from there. This explains the years of pains and problems that always improved with the occassional incidental round of antibioticsi here and there. That is until at 41, it took it's toll and I was diagnosed with rrmsi. Makes so much sense!

[Doxyi, Azith, Biaxin and Flagyli]  for rrms since October '05.  Added Amoxicillini 1gm twice daily and LDNi 4.5mg qhs October '07; Added Inositol[1gm] and Calcium Pyruvate[4-6gm] daily February '08, EDSSi was 6

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Began Wheldon Protocol for rrmsi October '05.  Currently OFF all abxi since June 26, '08 due to severe porphyriai. Added LDN 4.5mg qhs October '07.  All supplementsi.

I had back troubles and gum

I had back troubles and gum disease... both have cleared up on abxi .....the only problem with this kind of research is the problem with building resistence... they have no clue just how much of these problems are caused by cpni!

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treating reiters syndrome, cronic fatigue, heart symptoms, myalgia symptoms, started with doxcycline 200mg and rifampin 300mg in jan 15/05. switched to doxyi 200mg and azithromycin 250mg m.w.f in sept 06. after being on abxi for two years now doctors dont t

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