NAC and EB--lifespan of Cpn?

I have been researching and researching....omg. It seems to never end!  

As I have mentioned I have had a pretty difficult time with porphyriai--what a nightmare.  I have made the decision

to regroup and evaluate everything before I progress to another level.  Due to porphyria I discontinued taking iron tablets--I now realize

that I am seriously anemic.  That explains my current massive fatigue--I have been here before.  , 

 

Recently I discovered Dr. Terry Wahl and her impressive improvements  with MS.  She is practicing many food

principles that I used in the past (MS-Direct diet)  and I was much healthier at the time.

I am now consuming an incredible volume of vegetables, gluten and  dairy free and on and on.  It's quite an adjustment and I had a pretty good diet before.  

I am also now the  proud owner of a blender so pricey it will have to be willed to one of our kids. (Vitamix)

The porphyria  hugely improved after I began her protocol.

 

Now,  am reading about EB'si etc..  I have ordered NACi and will start this weekend.  

I need some help and hoping that someone has the answer--links are appreciated if that is easier.

My understanding is:  EB's can be killed by NAC.  EB's are the babies--we want to kill them to stop the disease from spreading.  In one article it was suggested to continue high doses  of NAC to prevent being reinfected--I like that idea. NAC is such a power nutrient that I see no downside with it--aside from the adjustment die off period.

So--if NAC esentially stops the replication of the baby bacteria--what is the lifespan of the other bacteria?

Does their lifespan match mine?

My nagging question.  lol

Thank you!

 Katherine

Comments

Katherine, don’t mistake

Katherine, don’t mistake organic chemistry with healthy eating, but yes, onions and garlic are both high in sulphur, but so is rotting flesh and skunk musk..............Sarah

A Journey through Light and Shadow

Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Does anybody know if the bad

Does anybody know if the bad reaction I got to just 600 mg NACi could have anything to do with the fact I have a slightly raised level of nickel in my red blood cells and nickel is partially blocking my ATP (special test done by McClaren Howard at Acumen in UK)?

 The reaction last nearly a week and messed up my endocrine system so I wasn't able to tolerate my usual thyroid meds.  Thankfully it is improving now but I am still getting episodes of hypglycemia which can be quite dramatic.

Yesterday I had an antibody test done for Cpni and will know the results in about 3 weeks hopefully.

 Bertie

ME/CFSi, adrenal insufficiency low dose steroids + flurdrocortisone, thyroid disease Armoujr + 25 mcg T3, 25 mcg T4, 20mg Propoananol, 200 Doxyi from 1/4/11, Azithro MWF from 1/6/11, Metroi 1st 5 day pulse 13/7/11

I suspect EBs have the

I suspect EBs have the ability to remain viable for a long time; even years, waiting for an appropriate host cell to engulf them in a vacuole and then for the exposed disulphide bonds in surface proteins to break, beginning the transition to the metabolically active replicating form. N acetyl cysteine (and other thiol-rich organic compounds) likely breaks the disulphide bonds extracellularly, producing 'NACi flu'. Such symptoms are evidence of a large bacterial loadi in the extracellular matrix beneath the respiratory epithelium. In the naive host an acute infection may progress rapidly, tailing off into an asymptomatic chronic infection.

My page on NAC may help: http://www.davidwheldon.co.uk/NAC.html<

D W - [Myalgia and hypertension">i (typically 155/95.) Began (2003) taking doxycycline and macrolide and later adding metronidazolei. No medication now. Morning BP typically 110/75]

David, I really really

David, I really really appreciated this answer.  Your work here has changed my life.  Thank you.

 

From David Weldon: 

N acetyl cysteine (and other thiol-rich organic compounds) likely breaks the disulphide bonds extracellularly, producing 'NACi< flu'. Such symptoms are evidence of a large bacterial loadi<i< in the extracellular matrix beneath the respiratory epithelium.

 

From a Live Stong article:

 

Thiol rich foods:  

Onions and cruciferous vegetables< contain thiols, sulfur-bearing chemicals with anti-fungal effects, says certified nutritional< consultant Phyllis Balch, author of the book "Prescription for Dietary Wellness." Thiols also prevent blood clotting and have cholesterol<-lowering effects. Cruciferous vegetables include broccoli, cabbage, cauliflower, Brussels sprouts, collard greens, kale and others. Chopping or chewing these vegetables activates their health<-promoting qualities. A study published in the February 2011 issue of the journal "Food and Chemical Toxicology" reported that a fermented cabbage product exerted significant inhibition of Candida.
http://www.livstrong.com/article/486365-an-anti-fungal-anti-parasites-diet/<

 

For the past several months I have been on the Dr.Terry Wahls diet. Of course, loaded with thiol rich foods.  Gluten and dairy free with 9 vegetables a day.  Kale kale kale.  lol

 

The transformation in my life in unmistakable.  I feel like my life is starting over.  A ways to go but functionally I am the best I have been in ten years—or more.   

The initial first few weeks of pure exhaustion, eye pain, sinus draining, some increased MS symptoms etc. has passed.  Then, intermittent fatigue issues.  Recently I started eating a cup of onions a day.  Back to being a mess.  But now I can see a pattern in my diet (onions one day, eye pain the next). 

 

I have no doubt that I have the Cpn infection after my  strong antibiotic response.    THANK you for this group! My goal is to become more efficient at “taking out the trash” before I look at antibioticsi again.

 

It’s really great to be at peace with what I eat.  It has been a very productive period of time for my family and me.  We are grateful.

 

Not sure which step is next for me but have some serious catching up to do with business and home etc. etc. etc..  Enjoying the brief interlude of feeling good.

 

Katherine

 

 

This was a detailed note and

This was a detailed note and when I reread it again I noticed a nice little comment.

I   am still working through some issues--though not nearly as intensely as before.  Starting to function better--forgot what it was like.

Still trying to determine if we can eat -- something--that will act like NACi.  Would rather not double up on supplementsi if possible.  Measuring the "dose"--that seems easier in a pill for sure.  

In this note--please anyone comment--  David Wheldon  said "and other thiol-rich organic compounds likely breaks the disulphide bonds" .  

Thiol rich organic compounds would include sulfur rich foods--correct?  

Thanks anyone! 

Katherine 

 THANK you for the geek

 

THANK you for the geek answer!  :)      I have read this several times--thank you for the link.   But  didn't see years--lots of reading....

Wow--  several years.  It is like a nightmare and a great opportunity at the same time.

The Art of War.  

To me this is good news--since we are confident that we can kill them in this state with NACi<.

I have many questions but could you please answer a few of them?

What makes a host naïve?  Nutrition?  Immunei system?  Some geneticsi?

" In the naive host an acute infection may progress rapidly, tailing off into an asymptomatic chronic infection."

What is an EB looking for in a cell ?  There are tons of other cells available. They set up shop with some folks and  not with others.

Your article on rosaceai and NAC was very helpful.

Thank  you again—I am in the process of healing and I am grateful. 

Katherine

 

 

That is a short time

That is a short time

DAILY:  NACi 2400MG , DHEAi sublingual , vit D3 , multi vits,./ Three times  a week: B12 injections (Hydroxycobalamin). Deer antler./  Once every few months methyl B12 Methyl injections

Page not found

Page not found

DAILY:  NACi 2400MG , DHEAi sublingual , vit D3 , multi vits,./ Three times  a week: B12 injections (Hydroxycobalamin). Deer antler./  Once every few months methyl B12 Methyl injections

You might want to take a

You might want to take a look at this:<

(http://cpnhelp.org/how_chlamydia_pneumoniae_<)

 

(One more time..... )

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

How long between its

How long between its entering the cell as a EBi and exiting the cell again as EB?

Thanks 

DAILY:  NACi 2400MG , DHEAi sublingual , vit D3 , multi vits,./ Three times  a week: B12 injections (Hydroxycobalamin). Deer antler./  Once every few months methyl B12 Methyl injections

Have a look at the Cpni

Have a look at the Cpni Handbook and you will find the science with supporting links (that work!). This diagram indicates times as upto 72hrs.<

speedbird

Thank you so much everyone

Thank you so much everyone for the help!  I read everything--but tired so could be missing details.  

72 hours is unbelievably fast for the whole cycle of enter, eat and exit.  No wonder I am so sick. That was enlightening.

What I can't find is how long they can live as an EBi.  They hang around for a cell to invade--how long can they survive in this state?  The vulnerable state for NACi. Is it a quick fly through--or are they hanging out for days?  Seems that the variations in time would occur due to the availability of the feeding station--the cell.

Also,  how long can they live in the cell before they exit?  And why do they exit?  Better eats down the road?  

Thanks again! 

Katherine 

 

 

 

 

 

Thank you.  I knew that I

Thank you.  I knew that I saw that somewhere!  SUPER fast!

Does anyone know how long they live in the cells?  I know that it varies greatly.

Katherine   

 

 

OK--I am replying to my own

OK--I am replying to my own post.  :) 

This is an excellent picture of the Cpni bacteria.  I think that I needed colors to further understand.  

   http://en.wikipedia.org/wiki/File:Chlamydophila_pneumoniae.jpg<

In this particular picture it shows the EBi entering the cell, it replicates, and the reticulate body (now with lots of kids) exiting the cell.   After they exit the cell is shown to be  living but could be dead. 

This indicates to me that it comes and invades, it eats, has babies, then leaves with the kids.  Sometimes it kills the food source.  Ingrate.

Do they always leave?  And if so does the whole family go at the same time? When they make their (hopeful)  exit they are then unprotected and can be blasted with NACi--correct?  :)  How long are they vulnerable?

 And.....why do they leave?  We want to encourage that.  We don't want to enable the kids and their offspring. 

 SO many questions!  

 Katherine 

 

Good question 

Good question 

DAILY:  NACi 2400MG , DHEAi sublingual , vit D3 , multi vits,./ Three times  a week: B12 injections (Hydroxycobalamin). Deer antler./  Once every few months methyl B12 Methyl injections

Katherine,  If Cpni is

Katherine,

  If Cpni is the pathogen that causes M.S. and it can become chronic then according to the Faroe Island Study for M.S. at least four generations.

Cpni, Mycoplasma, Chronic EBVi, M.S.(MRI, Spinal Tap-greater than 5 oligoclonal bands and VEP), PANDAS(OCD). Wheldon CAPi (started 12/08), Azithromycin/Clarithromycin(12/09), Lithium, Lamictal, NACi(2.4g/day), D3(15,000IU/day)