Mitochondrial dysfunction, MS, CFS, ALS, Chronic infection and CPn infection

Here is a very interesting piece of research about Mitochondrial dysfunction and chronic infection, tying together many disparate chronic diseasesi.  Also ways, apart from antibioticsi, that you can improve your mitochondrial dysfunction.
"Many chronic diseases and illnesses are associated with one or more chronic
infectionsi, dysfunction of mitochondria and reduced production of ATP. This results in fatigue
and other symptoms that occur in most if not all chronic conditions and diseases
Mitochondrial function can be enhanced by the use of various natural supplementsi,
notably Lipid Replacement Therapy (LRT) using glyerolphospholipids and other mitochondrial
supplementsi. In various chronic illnesses that are characterized by the presence of chronic
infections, such as intracellulari bacteria (Mycoplasma, Borrelia, Chlamydia
and other infections) and viruses, LRT has proven useful in multiple clinical trials. For example, in clinical studies on chronic fatigue syndromei, fibromyalgiai syndrome and other chronic fatiguing illnesses where a large majority of patients have chronic infections, LRT significantly reduced fatigue by 35-43% in different clinical trials and increased mitochondrial function. In clinical trials on patients with multiple intracellular bacterial infections and intractable fatigue LRT plus other mitochondrial
supplements significantly decreased fatigue and improved mood and cognition
Patients with chronic neurodegenerative, neurobehavioral and fatiguing illnesses commonly test
positive for systemic and central nervous system (CNSi) bacterial and viral infections. In
addition, other chronic illnesses where neurological manifestations are routinely found, such as
autoimmune diseases and other chronic illnesses and disorders, also show evidence of systemic
bacterial and viral infections that could be important in disease inception, progression and/or
enhancing the types and severities of signs and symptoms
Evidence of bacterial infections, such as Mycoplasma species, Chlamydia pneumoniae, Borrelia burgdorferi, among others, and viruses, such as human herpesvirus (HHV),cytomegalovirus (CMV), human herpes viruses (HHV) and other viral infections, have revealed
high rates of infection in the illnesses listed above that were not found in control populations.  Although the specific roles of chronic infections in various diseases and their pathogeneses
have not been carefully determined, the data suggest that chronic bacterial and/or viral infections
are common features of essentially all progressive chronic diseases.
Another common finding in chronic illness patients is mitochondrial dysfunction - 
characterized by loss of efficiency in the electron transport chain, reductions in mitochondrial
inner membrane transmembrane potential and reductions in the synthesis of high energy
molecules such as ATP"
To read the full article
fhdj.com/index.php/ffhd/article/view/26/318
and another similar piece of research linking mitochondrial dysfunction 
http://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-015-0310-y

Comments

Hi Irene,this is interesting.

Hi Irene,

this is interesting. I find the second paper more interesting because it is more scientific (I am an M.D., psychiatrist, scientist).

That is why the NACi might be so useful in some psychiatric disorders

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/<

I do not know anything about the LRT (lipid replacement therapy), but I heard someone kicked the chlamydia by using neem (Azadirachta indica)

www.mdpi.com/1420-3049/20/3/4180/pdf