methylation testing

Could someone please provide the link for a site that does the methylation testing and could someone please tell me if they know of a good brand of non yeast related b6

Thanks

Well, NSI B-6 from Vitacost is very good but their b-complex probably contains enough B6.  I think all B6 is yeast related, though.   I don't know about methylation testing: I just take plenty of sub-lingual methylcobalamin every day...............Sarah    
    
A Journey through Light and Shadow
Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Hello, clammed_up:    ... if you check the forums and go to "bookmarks on specific topics"    Louise graciously had provided many links regarding this topic there (if you are in fact referencing the testing done by Dr. Yasko).

But to cut to the chase -- here is the link:   http://www.holisticheal.com/health-tests/nutrigenomic-testing<

 

JeanneRoz

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

Yes its dr yasko info Im looking for thanks jeanne. Its alot of information to digest and organize in the mind isnt it. Im not sure if its a deficiency problem wih me or if its an actual blockage.Though, Ive always been b6, zinc and D deficient - Clinically relevant  as a cause of general unwellness. Ive just never been able to supplement with b6 due to a yeast sensitivity. One thing i do know is that I feel MUCH better when i eat red meat which suggests both a connection to lyseiene production/conversion problems and also b6 deficieny and /or metabolic pathway issues. Its cause and effect with red meat... Ive tested it repeatedly. I also do the sublingual b-12 sarah, I find it helpful yes, but I feel the most overall relief from increase in b6 which Im having difficulty figuring out how to do without getting nausea and sickish. Im trying natural factors b6 right now, apparently its made with fermented vege bacteria but no yeast. It still nauseates me but atleast symptoms are limited to the stomach.

I also read something briefly about a cetain rbc value that suggests methylation pathway issues even if it is just slightly off normal.. which mine is and always has been so maybe testing might shed some light and get things back on track for me. Hopefully I can adress this detox issue and get back to business, thanks for the link.

 

 

 

 

 

&nbs

Clammed,   I will dig around a bit and see if I can find some more links that you might find helpful to read.

Here is an old one from 2008;  http://www.cpnhelp.org/go_as_fast_as_you_can<

Don't let the title put you off.

Here is a blog link showing what you get for the testing in the form of someone's results; http://www.cpnhelp.org/methylation_pathway_testi<

Personally I have also had the testing a year ago and am taking the supports based on my results and further lab testings.

I started with the original Rich V. form of the Yasko protocol.   That form of his protocol can still be found on the internet at an older website. (which I may locate and put on another addition to this thread at some point so keep you eye open of it. To busy now to do that for you.)  I met him last summer at the Yasko Conference in Boston.  Very interesting man.  He eventually dropped the sam-e from his suggestions because not everyone can tolerate it and his suggestions were for untested people.    I started with the SAM-e in Aug 2008, made a huge difference in energy for me.    The older you are the more likely you will not be adversely affected by adding the SAM-e portion of Rich's form of the protocol so that might be good news.   I think he was being over cautious in his dealings with the CFSi community when he took to low level SAM-e out of the mix.

If you really want to understand the Methylation cycles, it does take a good deal of time, there are actually a least several interlocking interdependent cycles.  However to know exactly which of your cycles are deficient (affected) is truely helpful.   I have been off all abxi since being tested.   It was time for me to be off CAPi, I added it as another adjunct of which I do several to maintain my improvments.  However, I have had no back sliding into CFS symptoms. 

Just to note for you, Methylation supports re-myelination, Yasko worked with many MSers and those with metal toxicity prior to the movement into the more recent focus in tx of autism children.

Louise

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Clammed,

This is a post from the first link that I thought you might want to see. At this point we can thank Michele for her detail orientation.

At some point I will find Rich's orginal protocol article link and post it.

Note the date is from Sept. 2007.  Wish I had added these supplementsi back at that time, I was so, so, ill on early CAPi.  And likely incomplete Methylation was part of it and continues to be part of what I need for on going support to keep well after CAP.

Here is what Michele posted back in 2007.

Submitted by Michèle< on Sun, 2007-09-16 04:59.

At every turn it seems that NACi< is the most important supplement we take. It is with good reason that we should start with that, if it mobilises the metabolism as well as support the liver and kill EBs and moulds. What more will it be shown to do for us in the future?

It strikes me that Rich Van Konynenburg empirical protocol for kick starting the metabolism contains many of the vitamins and supplementsi<i< we already take.  Here is is with some notes about prices that I have added:

Protocol: The simplified approach would involve giving the following oral supplementsi< daily, all of which are available from Dr. Yasko’s supplement website at http://www.holisticheal.com<
 
    *¼ tablet (200 micrograms) Folapro (Folapro is 5-methyl tetrahydrofolate, an active form of folate, which is sold by Metagenics with a license from Merck, which holds the patent on synthesis). evitalhealth.com $17.49 for 60
 
    * ¼ tablet Intrinsi B12/folate (This includes 200 micrograms of folate as a combination of folic acid, 5-methyl tetrahydrofolate, and 5-formyl tetrahydrofolate, aka folinic acid or leucovorin (another active form of folate), 125 micrograms of vitamin B12 as cyanocobalamin, 22.5 milligrams of calcium, 17.25 milligrams of phosphorus, and 5 milligrams of intrinsic factor) evitalhealth.com $16.45 for 60
 
    * (up to) 2 tablets (It’s best to start with ¼ tablet and work up as tolerated) complete vitamin and ultra-antioxidant">i<i< from Holistic Health Consultants (This is a multivitamin, multimineral supplement with some additional ingredients. It does not contain iron or copper, and it has a high ratio of magnesium to calcium. It contains antioxidants, some trimethylglycine, some nucleotides, and several supplements to support the sulfur metabolism.) 
 
    * 1 softgel capsule Phosphatidyl Serine Complex (This includes the phospholipids and some fatty acids) iherb $24.19 for 60 is cheaper than holisticheal
 
    * 1 sublingual lozenge Perque B12 (2,000 micrograms hydroxocobalamin with some mannitol, sucanat, magnesium and cherry extract) wellnessworks.net $24for 100
 
    * 1 capsule SAMe (200 mg S-adenosylmethionine) I herb $20.98 for 60
 
   * 1/3 dropper, 2X/day Methylation Support Nutriswitch Formula (This is an RNA mixture designed to help the methylation cycle. It is not essential, but is reported to be helpful.) 

________________________________________________________

Michèle (UK) GFAi<: Wheldon CAPi< 1st May 2006. Daily Doxyi<i<, Azi MWF, metroi<i< pulse.

 

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

1. http://www.ei-resource.org/articles/chronic-fatigue-syndrome-articles/theory-of-glutathione-depletion-and-methylation-blockade-in-chronic-fatigue-syndrome/<

2. http://www.ei-resource.org/articles/chronic-fatigue-syndrome-articles/simple-methylation-treatment-protocol-for-chronic-fatigue-syndrome/<

 above article by:

Rich Van Konynenburg, Ph.D.
Independent Researcher and Consultant
July 18, 2007    please note the date it is the earlier version

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
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Clammed, Please pmessage me for more information if you like.

The concern about SAM-e is for those that test COMT++ and it also concerns the form of B12 that may give problems because of the amount of methyl donors causing difficulties for those folks.    But since Jeanneroz has just posted behind me and brought up this old disagreement once again.   It is just classic and here cautions are a bit overstated.   Most medical information is dispensed with get a proper MD to bad not many understand much of these approaches including CPNi treatment as I am sure that you are aware.     Jeanneroz and I are foes here just to say she much of the time tries to shoot anything that I try to share down, I really should expect it and only pmessage folks but then if anyone else could benefit what good would that do?    Between a rock and a hard place with her.   Suspect it will continue on and on and on.  She is always stating she is protecting the newbies well there is more to that than meets the eye.     Louise

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Re Simple Methylation Protocol --- quoting Rich Van Konynenburg, Ph.D. under "conclusions" of this link (also be sure to read possible reactions)  :

 http://www.ei-resource.org/articles/chronic-fatigue-syndrome-articles/simple-methylation-treatment-protocol-for-chronic-fatigue-syndrome/<

 "I want to reiterate what I wrote near the beginning of this article: This treatment approach must be entered upon only under the supervision of a licensed physician, to make sure that if there are individual issues that arise, they can be taken care of immediately. The treatment approach itself consists only of nonprescription supplementsi that are normally found naturally in the body and are necessary for normal biochemistry to take place. It would thus appear to be fairly benign on its surface.

However, it must be pointed out that restarting the methylation cycle after it has been blocked for extended periods, particularly in those PWCs whose general health has become quite debilitated, or those who have certain respiratory, cardiac, endocrine or autoimmune conditions, can present some serious challenges."

 

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

As I mentioned in my initial response to Clammed, Louise, you generously provided many bookmarks and links about the methylation protocol, Yasko,  etc......  My remark was not "shooting down" your comments or the simple methylation process. 

I am just  bringing to light the paragraph Rich mentioned about potential risks.... pointing out the disclaimer  this may not be "simple" for some people.  .... 

I personally do not believe it is wise to post protocolsi such as this without also pointing out the the disclaimers (as mentioned by Rich).......  Especially, since we here are not doctors.     Some may rush out and buy the supplementsi (without reading) take them, without having a clue, and get more sick.

It wouldn't matter who posted this information.... I would still have the same comments. 

 

 

 

 

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

We are all entitled to our own opinions Jeanneroz.   One can either be on the introducing side of information or the discouraging side.   People can read or they would not spend time here.  Since most doctors will not support a request for emperical CAP, some readers do it anyway.  

In the same way, and most doctors have long since stopped thinking about things like methylation (learned early on in med school).   

Disclaimers are just that diclaimers they are in the front of most health related material in printed form, for the protection of the author presumably.       Yet the authors believe so much in their material they publish it in the attempt to help people.

Thanks for protecting the world from the information in my responses, you have made it your mission and I have not missed it.   And I have noticed that it does not hold true across the board and yes you do single me out, perhaps for the past several years.   Others have noticed too.     I have come to expect it and you don't disappoint! 

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <
The inclusion of your paranoidal rants (with statements  I am on some kind of mission against you),  in your posts really is becoming monotonous and a waste of site space, Louise

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

Dito!   Monotonous as your several years of contradictory postings on a multitude of topics.  I guess it is all about perspective here and we will never see much from the same.   What works for me seldom works for you so you warn everyone.  For several years, I just ignored the situation.  I am finished with that now and will speak my truth as I see it. 

People are free to ignore my posts certainly.   However CAPi has worked for me, been symptom free for several years now and doing well.  Yes, certain adjuncts have worked very well for me as adjuncts of CAP, many of them I found accidently by reading, the information was here, scattered through back posts.  So I will continue to post here on occasion and you will likely continue to try and correct peoples impressions of my posts or deflect the flow of my comments, which you clearly assume are deleterious and mischievious.    Be that as it may, I will post helpful information despite your watchful contradicting eye and disempowering posts.    You will be wasting more space as if that made a difference really.

Many people quite CAP within 6 months because of the inability to tolerate the treatment.   My suggestions are for those of them that choose to consider what has helped me.   You have it sees over time stood in opposition to what has helped me get to my current level of wellness off CAP.   Methylation is one of the major adjuncts that has helped me get my life back.

It seems odd that one who has made the improvements that I have is in constant battle with you who does not feel well enough according to your posts.   Much of what worked for me did not help you at all.

In many ways I took my direction from the sharings that Jim posted, what worked for him generally worked for me.   Since he no longer posts I share what my successes have been.   Paranoid perhaps,  but you consistently are in my face.   Now I expect and will continue to share and deal with you as needed.

This topic is about methylation testing.

This topic is about methylation testing.  It is very expensive for those on limited income. Then there are follow up labs to refine suppleentation, again very expensive.  It is the best of the best of the approach to be tested certainly, I wish I had done it several years earlier, I let the cost factor influence me from it.  

I have studied the protocol in depth.   And in reality most people are doing the Yask_ protocol without a provider as with CAP such providers do not exist.    I know this as I attended the Yask_ protocol conference last July 2010.   There is an effort to now take the protocol and expand it towards populations with dyfunctions other than Autism such as CFSi/ME that is why Rich VanKonyneneburg was asked to present.

Certainly I add all of this for those who might chance to read it and not to convince you of anything.   You distane for me was begun years ago and shared directly to me privately and until quite recently I just sucked it up but those days are gone, so I just guess that you'll continue to play down whatever I share here and I need to say that openly as any times as it takes.  

Clearly Jeanneroz, we are polar opposites, you the ultra conservative with your warnings  and I the liberal who ads adjuncts and gets good effects from what I try..  

Clammed I hope that you get what you need to add methylation in the proper way so that it may do you some good.   

And truely this has been the intention of my post. 

As with most things pick and chose and leave the rest, do your homework and keep informed.  

And I give you the credit to be able to read any disclaimers for yourself without them having to be extracted from articles so that you will be sure to see them.

Now we will hear from Jeanneroz, as she always must have the last word!

 

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <
This on going feud is very discouraging for everyone reading these posts, we are all sick here!!!! I am sick of reading this!!! Please stop!!!
FMSi,CFSi, 15 years,CPni antibodies,mycoplasm pn.,leison on posterior pituitary. Started CAPi end of Dec. 08 minoi.100 daily, azith. 250 MWF all supplementsi,compounded T3 therapy.

No PattiR were are not all sick here.    I was sick, I took CAPi treatment started in 2007 and adjuncts.   Now I am quite well in 2011.   You might consider the Simple Methylation supplementsi, they certainly are part of my inmprovements and maintainance of imporvements.  

I wish improvements for you and everyone else here.  Most people stop reading things they don't like. 

You could perhaps not read anything with my name on it to bring you comfort, you have just perpetuated it by adding another post in the same vein.

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
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