Lumbal puncture for Cpn diagnosis (urgent)

Hello together,

the last weeks my tingling sensations worsened significantly. I have also muscle twitching now and a beginning numb feeling in the face, arms and legs. And fatigue of course. My neurologist wanted to do a lumbal puncture in the past, but I refused to let it do.

The symptoms are so strong now that I have to see a neurologist, and I think he'll insist that a LP must be carried out. I will ask the neurologist to look for Cpni, but I'm not sure which tests are needed. Can someone help me? I know a PCRi for Chlamydia pneumoniae has to be done. Does it also make sense to measure IgGi-antibodies against Cpn in liquor like it is done in Lyme disease? Any other senseful tests?

My Cpn serologyi in blood is highly positive: IgG > 500 (norm < 22) and IgA= 60 (norm <22).

It's a bit urgent. Thank you.

The spinal tap is to check the CSF for signs of MSi (oncological banding or something like that). But the IgAi being positive indicates an active or recent CPni infection... good candidate for CAPi!!!

We find consulations, we learn tricks with which we deceive ourselves, but the essential thing - the way - we do not find. Listen to the river...

"The spinal tap is to check the CSF for signs of MSi<i< (oncological banding or something like that)."

There are quite a few studies which looked for signs if Cpn in CSF. But I'm not sure which tests make sense and if a "normal" lab can do this. I'm afraid of getting back false negative results.

Hi,

i really don:t know if you should have the LP, all i know is that i did have one, days after my positive MSi diagnosis. The dxi didn’t change, the lesions, shown by MRI, confirmed my MS.

but, the LP made me sick, more sick than ever before, but i didn’t ask why it was needed. What extra information would it give?all i could suggest is that you should ask, always ask why and  give yourself time to decide. Maybe your Neurologist will have a good reason for performing this, potentially, tricky procedure.

good luck.

Jane

MSi symptoms from 2001, DXi RRMSi in 2008, following, a change of hospital who sent me for an MRI, precipitated by some sight loss. Took Interferons, on and off. Prescribed  chemo infusions to slow pro

Markus, a lumbar puncture is just one way of showing that someone has MSi.  Jane had one and hated it, I didn't have one because my neuroi didn't think there was any point in wasting hospital time and money and his precious time on my lost cause..

You have already had a c pn serologyi test which showed a much higher result than mine, so I would just get on with taking all the abxi and supplementsi and concentrate on getting better.  Maybe you don't have a positive MS diagnosis, or maybe you do: I can't remember, but maybe it doesn't really matter.  What matters is getting healthy once again............................Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Hi All, can anybody tell me what these readings are, high or low etc     chlamydia psittaci 1;32, chlamydia pneumoniaei ifa titre 1;512,, chlamydia psittaci ifa titre 1;512, it also said consistent with recent c.psittaci infection,  can anyone give me their views on the above results. much appreciated. thanks. Robert.

Hi Sarah,

I don't have a MSi diagnosis. In the meantime I had a MRI brain scan (native) and everything was normal. So I think it makes no sense to let a LP be done. Symptoms are still strong, but maybe the brain is not affected and the tingling comes from ther peripheral nerve system.

By the way Sarah, are you still on ABXi or are you completely off?

Markus, no I haven't needed abxi for c pn since 2008, but I did take oe five day course of roxithromycin a few years ago, to cure a septic thumb.....................Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

twitching is very common in cpni symptoms

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