LDN for Fibro

Inadequate Thyroid Hormone Regulation as the Main Mechanism of Fibromyalgia: A Review of the Evidence<

Fibro is still highly controversial but some may find this< article interesting as well....

"Competing etiological hypotheses of FMSi account for only a fraction of the symptoms and objectively verified abnormalities among patients, and no treatment other than thyroid hormone therapy has been shown to relieve patients of FMS status. This review of the published research literature shows that inadequate thyroid hormone regulation is the most likely underlying mechanism of the symptoms and objective abnormalities of patients who meet the criteria for FMS."

  JeanneRoz

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

Wow, seems like that article deserves a topic of it's own, Jeanneroz. 

I personally don't think LDNi has any direct effect on the thyroid it applies to a totally different aspect of overall balance. 

Fortunately for me, my thyroid is functioning well, guess most of my CPni chose my liver as it's location of preference. 

Still LDN has worked well for me for general wellbeing for the last 7 months.

I guess the point is to get the word out about LDN not so much a discussion about Fibro Dxi and symptoms.  My topic was that LDN can be of useful benefit to people beyond the original thinking that LDN is just for MS folks because for over 1 1/2 years I did not have a clue that it could be used by anyone other than people dx with MS.

I found it useful that there are websites that are springing up to alert different patient populations to the diversity of diagnosis that might get benefit from it. 

Louise

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

I have secondary hypothyroidism & take Armour thyroid for many years now.  It doesn't abate my FMSi nor have I had a substantial change result from my treatment.  Who knows if years of undiagnosed hypothyroidism contributed to my FMS, along with 5 MVA's & a serious motorcycle crash.  Lots of physical traumas in this gals life.

 

peace

r

 

CFIDSi/ME, FMSi, MCS, IBSi, EBVi, CMV, Cpni, H1, chronic insomnia, Chronic Lyme, HME, Babesia, Natural HRT-menopause, NAC 2.4 gm,Full CAP 6-2-07, all supplementsi+Iodorol, Inositol-depression, ultra Chitosan, L lysine Pulse#27 04-19-10 1gm Flagyli/day-5 days<

Ruthless, have you ever  considered giving LDNi a trial?   Louise
  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Louise, your statement "I personally don't think LDNi<i< has any direct effect on the thyroid it applies to a totally different aspect of overall balance." is exactly why I posted this as an additional read below your's.  Not for discussion per se, just additional info to digest....

 Unless, (IMOi, and others) the HPA (and thyroid) is balanced LDN will not (probably will not) be beneficial  to FM (if one believes HPA/thyroid balance has a role in FM and according to this study it does). 

There are many people who view LDN as a "cure all"  without having investigated what may really be causing their problems

There are quite a few on some of the other "boards/groups"  that complain about CFIDSi,FM etc. AND know they have stealth bacteria, (or thyroid problems) but are not willing,  don't understand, or don't want to go through ABXi therapy or treatment -- some really do believe "hey, I'll try LDN" (when they really need ABXi combo therapy... or HPA analysis)   

Not really their fault, of course, most depend on their doctors.  It is also limited to each individual's understanding, ability/willingness to comprehend.  Most of us here on this site, IMO, are exceptional in trying to educate and help ourselves.

LDN is proving to be beneficial to many, many diseasesi. I just thought I should play Devil's Advocate regarding FM.

Those who do not have any HPA issues with CPNi are quite lucky.  You, especially, since you have both Bb and CPN. The imbalance definitely  plays havoc in this recovery when adrenal/thyroid issues play into the mix. 

As an aside, my personal experience with LDN was horrible.  (And, I didn't post this to be negative) I truly wanted it to make me feel better.  I am not ruling it out, but at this point in my treatment it was just not a pleasant experience (and I believe the reason it wasn't working for me has to do with my HPA issues being caused by the CPN) 

Also, didn't you originally have 3 links posted?

JeanneRoz

 

 

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

Hi, Ruthie!

How much Armour do you take and how long have you been on that dose?  Just curious

You HAVE had a lot of physical trauma to the muscles in your body with all your crashes...:(

 

JeanneRoz

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

Hey Sunshine!

I take 30 mg 4 X a day & 2 tabs of Cytomel along with 2 Iadoral & 2 sea kelp tabs.

Yes... I have the lumps & bumps of scar tissue to prove it.  so much for someone saying to me I make this stuff up!!

 

peace

r

 

CFIDSi/ME, FMSi, MCS, IBSi, EBVi, CMV, Cpni, H1, chronic insomnia, Chronic Lyme, HME, Babesia, Natural HRT-menopause, NAC 2.4 gm,Full CAP 6-2-07, all supplementsi+Iodorol, Inositol-depression, ultra Chitosan, L lysine Pulse#27 04-19-10 1gm Flagyli/day-5 days<

yoi Louise.  I take a boat load of meds with the sleeping stuff for my chronic insomnia.  I am trying to keep this as natural as possible aside from that. 

I haven't considered LDNi & really wonder if my doc would prescribe.  I sort of thought it was for MSi more than ME & FMSi & Lyme. Do you have some links that show some successes with it, I would appreciate it if you attached when you had a moment.  YOu are such a good science person!

Thanks

peace

 

CFIDSi/ME, FMSi, MCS, IBSi, EBVi, CMV, Cpni, H1, chronic insomnia, Chronic Lyme, HME, Babesia, Natural HRT-menopause, NAC 2.4 gm,Full CAP 6-2-07, all supplementsi+Iodorol, Inositol-depression, ultra Chitosan, L lysine Pulse#27 04-19-10 1gm Flagyli/day-5 days<

I have added the important comment made by Jeanneroz to the bookmarks forum for ease of finding the topic on future reference.  Thank Jeanne for sharing it.

Inadequate Thyroid Hormone Regulation as the Main Mechanism of Fibromyalgia: A Review of the Evidence<

Fibro is still highly controversial but some may find this< article interesting as well....   

"Competing etiological hypotheses of FMSi<i< account for only a fraction of the symptoms and objectively verified abnormalities among patients, and no treatment other than thyroid hormone therapy has been shown to relieve patients of FMS status. This review of the published research literature shows that inadequate thyroid hormone regulation is the most likely underlying mechanism of the symptoms and objective abnormalities of patients who meet the criteria for FMS."

JeanneRoz

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Ruthless, Nice to hear from you it has been quite some time I think.   Would love to read an update blog about your journey as of late.

In response to your comment, "I haven't considered LDNi<i< & really wonder if my doc would prescribe.  I sort of thought it was for MSi<i< more than ME & FMSi<i< & Lyme. Do you have some links that show some successes with it, I would appreciate it if you attached when you had a moment.  YOu are such a good science person!"

I have to say that having my doctor prescribe it was the easiest thing that I have negotiated with him.  And it is really inexpensive.  If you decide to try it pmessage me and I will tell you the names of the compounders that are the best to use for compounding.  

I'm needing to get ready to be off to church just now so will get back to you with some links to read.

As my provider discussed some folks find it of value and some not.   I am one who added it to my list of adjuncts that do help ME.   Most of the folks that have difficulties with it have MS and they need to work into full dosage slowly to avoid muscle spasms.  There is info on the web, several books, and even some videos on the web, full length presentations of some of the speakers from the annual conferences. 

I'm glad the topic caught your eye and which that I had know to ask to go on it months before I did.    You can read some of my comments about it in my blog pages if you like.   If you track my posts you will come to the ones that involve LDN links yourself, I have posted them several times over the past year or so. 

Got to get going now.   Great to hear from you.   Louise

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Ruthless, here you go, the link to the post I entered 6/30/2009 titled;

LDNi books and websites;  http://www.cpnhelp.org/ldn_books_and_websites<

 

After my last entry to you I did locate your brief blog addition from earlier today.     Louise

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Ruthless, A few more links;

An article discussing LDNi<i< for Fibromyalgiai<i< http://www3.interscience.wiley.com/cgi-bin/fulltext/122350858/PDFSTART<

Another article; Low-dose naltrexone for disease prevention and quality of life; http://www.ldn4cancer.com/techpapers/ldn_for_disease_prevention_quality_of_life.pdf<

That is enough links for this this comment to be posted.

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Ruthless, more links;

This link to a video from the 2007 Conference.   The speaker is a pharmacist;

http://www.youtube.com/watch?v=-2XWfJF4dRE&feature=related<

Also this speaker from the same conference;

http://www.youtube.com/watch?v=kclMin66Sf4&feature=related<

http://www.lowdosenaltrexone.org/ldn_and_ai.htm<

I think that the 2008 LDN Conference is available on the internet but at this point I would have to google for the link and you can do that yourself if you have any more interest.

Blessings to you and yours,  Louise

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

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