Jaundice (icterus) after 3 weeks Doxy

I would appreciate any feedback from somebody, who developed icterus (jaundice), while taking Doxyi. I started in November 2010 with Doxy in the first week 50mg daily, in the second week 75mg daily and in the third week 100mg daily. After the third week I started to feel very bad (dizziness, fever, trend to collapse, shivering, feeling very depressed, the blood sugar level was increased, although I am not diabetic, my skin became yellow but the sclera remained white). I stopped the abxi immediatly and now after 4 weeks, my fever is gone, the blood sugar is ok but my skin is still yellow.

 

Does anybody had a similar experience or has anybody an idea? What does this icterus means and what can I do? Personally, I think it’s a liver problem caused by Doxy.

 

I would be very thankful for any opinion or experience sharing.

Raluca

Did you start the doxyi without taking NACi? I'm assuming, since you're asking for doctor referrals, that you have started the protocol without a doctor being involved?

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Did they test your liver? Where your eyes yellow too?

I had/have a bit yellow skin but not eyes. My liver tested ok. I read that yellow skin can come from beeing hypothyroid and that is my case.

Good luck with treatment,Best Wishes from Maria

Cpni since sep 2006. Autoimmune thyroid,hypofunction.levaxin,b12+folic acid">i.All classic cpn,porphyriai and toxinsymtoms.Not able to work.Selftreating cpninfection with AllicinMax(garlic), NACi, high vitamin D3. CAPi for over 3 years. Back to work and life

Hello Raluca,  I would recommend you start reading the "CPNi Handbook" . (as well as the other Tabs in the upper right-hand corner of this site Laughing.

 Whether you are self-treating or under the care of a doctor, it is recommended you have an initial series of blood tests run; and, had you done so this may have given you an answer about why you turned yellowFoot in mouth.  I definitely would have them run now.  (Forgive me, if I am incorrect in assuming you didn't have this done...)

http://www.cpnhelp.org/bloodtests<

Also, it is important to be taking the NACi and all the supplementsi.... one of the more reputable doc's who treats CPN usually has his patients start the supplements first before taking any ABXi

Doxyi made me very ill in the beginning and I had to start with only 100 mg every other day, and build up slowly.  I had many of the symptoms you mention.  All of us are different..... so we have to work with what are bodies will tolerate, keep the toxins flushed out, and GO SLOW. 

There is a wealth of information here on this website, in addition to the experiences of those of us who have been (and are still going) through it.  

JeanneRoz

 

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

 Yes, I started the doxyi without taking NACi - do you think this is the cause of my liver-problems? Does NAC make such a big difference?

Unfortunately, I haven't  found a doctor until now....so I started the protocol all by myself. I know it was risky, but what should I do? My MS-Symproms have been getting worse since February 2010.

 

Hello Maria,

thank you for your answer. I also have only a yellow skin, like you. The eyes are not yellow. My liver parameters were light elevated. They didn't test me regarding Porphyriai and they didn't run any tests for the thyroid. This is a good idea, I will ask my GP about it. May I ask you how long your skin has been yellow? Are you on abxi now?

good luck for you too and all the best

 

Hello JeanneRoz ,

thank you for your advices. I will study carefully the link you were so nice to send me. You are correct in assuming I didn't run any blood-tests before I started with Doxyi. After getting the yellow skin, I went to a doctor  and he made some blood-tests- and found that my liver parameters are elevated. Does this mean that I basically can not take any abxi with my fatty liver and my elevated liver parameters? ( they found that I have a fatty liver by doing a ultrasound).

I am very grateful for all this information on this website - I am overwhelmed by the amount of knowledge  of all the members, who are sharing with generosity their experiences. 

best wishes

raluca

Yes! THe N-Acetyl Cysteine (NACi) is important. It will help protect your liver, as will milk thistle and a couple of other things I can't reference at the moment. (Very distracting, noisy, floor-sanding is going on in my house right now.) NAC will help your system protect against all the toxic results of cpni die-off.

I was like you; very anxious to start the treatment immediately because my symptoms were hitting me hard and in great numbers.  Just remember, you can harm yourself by doing 'too much, too soon', so please read what JeanneRoz has directed you to and feel free to ask us as many questions as you need to.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Your welcome raluca, my skin have been a bit yellow for years. It started after I got ill 2006.

It looks like I have a great tan, but more yellowish. In my palms you clearly see that its yellow.

It started before any treatment for cpni. My aunt (a nurse) at one point asked my mother how my liver was doing. My liver was always tested normal, but when I was at my worst numbers were getting higher but still normal.

My skincolor got better after beeing on thyroidhormons.I think when tyroidhormones are better all inner organs work better and detox is also easier. My skincolor is diffrent during the day. When I have more dieoffs its often more yellow. I think its bacause of cpn and that thyroidhormones are blocked from all toxins, and then I get more yellow. Also vitamin d3 is helpful, when I sit in the sun in the summer I can clearly see the yellow disappear and my skin get normal color. When I feel im at my best my skincolor is  more normal.

I did read from several that yellow skin can be from hypothyroid and I also talked with a coworker with thyroidproblem she also had it.

But of course liverproblem is the first thing to check when skin turns yellow. My bilrubinlevels were always fine.

Yes im on abxi now and everything else that I treat with. Im feeling better but still not cured.

Thanks for wellwishes!

Best Wishes,Maria

Cpni since sep 2006. Autoimmune thyroid,hypofunction.levaxin,b12+folic acid">i.All classic cpn,porphyriai and toxinsymtoms.Not able to work.Selftreating cpninfection with AllicinMax(garlic), NACi, high vitamin D3. CAPi for over 3 years. Back to work and life

 

Hello MacKintosh,

thank you for your quick response and for your support. It means a lot to me to know that I am not alone in my battle against this nasty bacteria.....It's good to know how important NACi is, I went today at the pharmacy and I bought some. I am a little anxious to start with it, because  I heard NAC has the ability of binding heavy metals and, if my liver cells are damaged and  not able to excrete this NAC-bound metals, the risk of redistribution is very high. And when heavy metals are redistributed, they are usually redistributed to the brain, causing a MSi-relapse. ( I had a bad experience with selenium intravenous, and selenium bind heavy metals, too.)

I will start with very low dose and I will see what happens.

Best wishes

Raluca

 

Hello Maria,

 Thank you for sharing this informations with me. My skin became yellow after I started with doxyi. But, like you, the skincolor is different from one day to another: sometimes is darker, sometimes is lighter. And the palms and the soles are more yellow than the rest of the skin. It makes a lot of sense when you explain the role of the thyroidhormons for the inner organs and for the detox. But if my thyroid isn't properly working I should put some weight on, I think. And my problem is that I am constantly losing weight in the last 4 weeks. I am very underweight for my height. I will make  blood-tests for the liver and for the thyroid and then will see.

Again, thank you and take care,

Raluca

 

Raluca, Don't be surprised if the NACi causes you to feel like a cold is coming on, or creates sinus drainage. We call that 'NAC flu' and it can be minor and last a couple of days, or it can feel like you are starting to come down with the flu and it can last a couple of weeks.

Don't be alarmed by it; it's actually the 'poor man's' test for cpni infection. A flu-like response is a good indicator for a cpn infection.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

I just want to clearify that this blocking of hormonereceptors that block thyroidhormones happens to all cpnsick that have problems with toxins from cpn. So we can have good blood levels of thyroidhormones but cells can not use it, because hormonereceptor is blocked.

 I cant remember if it was the toxins itself that cause the blocking or of it was cytokinesi that cause the blocking. Either way we cpnsick have problem with both the toxins and cytokines.

So this blocking have nothing to do if our thyroid is sick or not. But of course the effect will be harder to deal with if we are low in thyroidhormones to start with. I watched my mother get more yellow some days and even my brother once. They have cpn but not thyroidsickness.

Best Wishes, Maria

Cpni since sep 2006. Autoimmune thyroid,hypofunction.levaxin,b12+folic acid">i.All classic cpn,porphyriai and toxinsymtoms.Not able to work.Selftreating cpninfection with AllicinMax(garlic), NACi, high vitamin D3. CAPi for over 3 years. Back to work and life

Ok, good to know about this NACi side-effects. Unfortunately, today i was lying in bed with a real cold. So I think i will wait a couple of days to get better and then I will start with NAC.

Do you have any experience with heavy metals and NAC?

best regards,

raluca

 Very interesting, Maria. And how can I un-block the hormonreceptor? Or it is nothing to do, just wait until the hormonreceptors became free from toxins/cytokinesi?

Anyway, I am very interested to find out if my thyroid is sick or not.....

best wishes,

raluca

 

 

Sorry dont know how to unblock the hormonereceptors.  But moppers  nd vitmin c might help since it helps with toxins.  Good luck with testing.

Best Wishes,M

Cpni since sep 2006. Autoimmune thyroid,hypofunction.levaxin,b12+folic acid">i.All classic cpn,porphyriai and toxinsymtoms.Not able to work.Selftreating cpninfection with AllicinMax(garlic), NACi, high vitamin D3. CAPi for over 3 years. Back to work and life

Hello Maria,

what do you mean by taking moppers? What exactly are moppers? Do you mean charcoal, medicinal clay, psyllium seed husks, zeolite etc?

 thank you for your well wishes and good luck to you, too.

Raluca

Yes, I mean charcoal. And also vitamin C is helpfull for toxins.

Glucose  and carrots help with porphyriasymptoms.

Thanks, Maria

Cpni since sep 2006. Autoimmune thyroid,hypofunction.levaxin,b12+folic acid">i.All classic cpn,porphyriai and toxinsymtoms.Not able to work.Selftreating cpninfection with AllicinMax(garlic), NACi, high vitamin D3. CAPi for over 3 years. Back to work and life

Thank you, Maria. I tryed to take charcoal a couple of times and each time I got constipated. Do you have this problem, too?

kindest regards, raluca

I never tried it myself. Best Wishes,M

Cpni since sep 2006. Autoimmune thyroid,hypofunction.levaxin,b12+folic acid">i.All classic cpn,porphyriai and toxinsymtoms.Not able to work.Selftreating cpninfection with AllicinMax(garlic), NACi, high vitamin D3. CAPi for over 3 years. Back to work and life

Hope everything works out
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