Ivermectin

Ivermectin has 'popped up' a few times on this site.  I know a couple of people have treated 'worms' (sorry don't know full medical term) with it, because a few doctors believe this gets in the way of the immunei system functioning (and therefore might be helpful to us on CAPi, if we are unfortunate enough to house these beggars as well).

I believe Elinor tried it some months ago, and I was wondering if she felt that it worked.  It is anti-parasitic but I am not clear if it is an antibiotic or not?  Would the antibioticsi on CAP not go a good way to destoying them?  presumably not ....

Any thoughts, experiences .... ?  I am a little intrigued ....

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M.E./CFSii 20 years, intermittent.  Wheldon Protocol - Started NACi and supplementsii Sept 2007. Doxyii and Roxy full dose by Dec '07.  First Flagylii pulse January 2008.

Dr AW perscribed Ivermectin

Dr AW perscribed Ivermectin for Paula.  He said that he found microfilariael worms in all blood samples he had seen where people had a diagnosis of CFSi.  He thought that they blocked the lymph system, meaning your body couldn't flush away any toxins as well.

I was a bit sceptical myself and Paula didn't notice any improvement after the Ivermectin course.

We have another telephone consultation with him in a couple of months.  I'll ask him then.  In meantime, others here may be able to give more details on worms and Ivermectin.

Mark

UK Carer of bedridden Severe ME/CFS Feb06. CPNi dx. Apr07. Samento 15 drops per day July07.  2400mg NAC 200mg Doxyi Jan08.  300mg Roxyi Apr08.

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UK Carer of bedridden Severe ME/CFS Feb06. CPNi dx. Apr07. Borrelia dx Sept08. Samento 15 drops per day July07.  2400mg NAC 200mg. Doxyi Jan08.  300mg Roxyi Apr08.

well, that is interesting. I

well, that is interesting.

I am especially interested in anything that works on the Lymphatic system.  Us ME'er seem to have blockage due to the post exertional malaise - lack of ability to tolerate exercise.

keep us posted!

CFIDSi/ME 26yrs, FMSi, IBSi, EBVi, CMV, Cpni, chronic insomnia, Lymes, HME, Natural HRT peri-M, NACi 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, Pulse#10 1000 mg 3 days & 750mg 2 days, 5-17-8

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CFIDSi/ME 32 yrs, FMSi, IBSi, EBVi, CMV, Cpni, chronic insomnia, Lymes, HME, Natural HRT peri-M, NACi 2.5 gm, 6-07 Doxy 200 mg day pm, Azith 375 mg M/W/Fday, Pulse#14 1000 mg X 5 days 9-19-08

Antibioticsi Help Combat

Antibioticsi Help Combat Dangerous Tropical Disease

ScienceDaily (Jun. 27, 2005) — The disease is triggered off by the bite of an infected mosquito: together with its anticoagulant the mosquito pumps threadworm larvae into its host's body. These gravitate towards the lymph nodes, where they grow into threadworms which may be up to ten centimetres long. The body reacts by producing inflammationi which halts the flow of lymphatic fluid. The consequence of this is that arms, legs and genitals swell to monstrous proportions – hence the name elephantiasis. More than 120 million people worldwide are infected with the pathogen wuchereria bancrofti.


Adult wuchereria worms have a lifespan of up to five years. During this time they produce millions of offspring, what are known as micro-filariae, each of them smaller than the full stop at the end of this sentence. If the host is bitten again by a mosquito, the micro-filariae are ingested together with the blood. Inside the insect they mature into infectious worm larvae, thereby completing the circle.

'Although the drugs currently in use kill the micro-filariae, they largely leave the adult worms unscathed,' Bonn parasitologist Professor Achim Hörauf explains. 'Due to the long lifespan of the wuchereria worms, therapy lasts several years, during which time the symptoms continue to persist.' What is more, the drugs may cause severe side-effects.

De-worming the roundabout way

Yet the threadworm, too, has a sub-tenant, and this may be its Achilles heel, since in each wuchereria worm there are specific bacteria which are absolutely indispensable to the parasite's survival. If these bacteria die, the parasite will also die sooner or later. 'This is why wuchereria is susceptible to antibiotics which are normally used against bacterial infectionsi,' Professor Hörauf emphasises. One example is doxycyclin, which has been used for decades for infections of the respiratory tract and the gastro-intestinal tract.

In their study the medical experts in Tanzania treated 72 male patients for eight weeks with doxycyclin or a placebo. Initially the patients' blood was swarming with micro-filariae: the researchers counted up to 1,300 of them per millilitre of blood. Eight months later they had almost completely disappeared; only in one patient were sporadic micro-filariae still detected. However, the proportion of micro-filariae also dropped in the placebo group – an effect which was probably due to the improved care given the test persons.

Unlike the drugs in use up to now the antibiotic also killed off the adult worms. Fourteen months after being treated with doxycyclin the doctors were only able to detect the typical movements of the worms ('the dance of the filariae') on ultrasound in one in five patients. In the placebo group the rate was 89%. In the doxycyclin group the concentration of specific worm proteins in the blood fell by over half.

Effective, cheap, few side-effects

'The importance of these findings for therapy should not be underestimated,' Professor Hörauf emphasises. 'The mature worms are after all responsible for such symptoms of the disease as the extreme swelling of the limbs. In the past there was no effective and reliable method of combating them.' The effectiveness of the antibiotic might be even greater than what was measured: 'We cannot exclude the possibility that several patients became re-infected in the months following treatment with doxycyclin. It is therefore quite possible that all the worms were killed and the remaining 20% are the result of re-infection which would no longer occur if infection was effectively prevented.

Doxycyclin has been used for many years and has only minor side-effects. However, in young children it may cause irreparable damage to the teeth and slow down growth of the bones. For this reason the antibiotic should not be used during pregnancy, either. For adolescents and adults, however, the drug is harmless. Moreover, it is comparatively cheap. 'Its biggest advantage is that it is already licensed for medical use,' Professor Hörauf points out. 'Elephantiasis hits the poor most of all. It is therefore not likely that the pharmaceuticals industry will develop completely new drugs.'

 

Male 35 (Hamburg-Germany),CFIDSi, IBSi, Enterovirus, Cpni,treated Enterovirus with Inf-y,Inf-a.,Ribavirin. Started Wheldon Capi on 02/19/08, Currently NACi 2400, Doxy 2x100, Biaxin 2x500, Metroi pulses,pyr

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Male 35 years (Hamburg-Germany),CFIDSi, IBSi, Enterovirus, Cpni for years positive. Started Capi on 02/19/08, Currently NACi 2400, Doxyi 2x100, azi 250, tinii pulses clarithromycin 2x500, metroi pulses, 12 g calcium pyruvat

And another one - I think

And another one - I think with the doxyi on board nobody should worry about microfilariea 

 

Antibioticsi Help Combat Dangerous Tropical Disease  
 Threadworms dependent on bacteria to survive  
 An antibiotic which has long been used to fight infectionsi of the respiratory tract and intestine also seems to be able to defeat the dangerous pathogens causing elephantiasis. This is proved by a study carried out by parasitologists from the University of Bonn together with colleagues from Hamburg, Liverpool and Tanzania. Their findings have now been published in the prestigious medical journal The Lancet (vol. 365, May 2005). The disease has previously been usually incurable.

The disease is triggered off by the bite of an infected mosquito: together with its anticoagulant the mosquito pumps threadworm larvae into its host's body. These gravitate towards the lymph nodes, where they grow into threadworms which may be up to ten centimetres long. The body reacts by producing inflammationi which halts the flow of lymphatic fluid. The consequence of this is that arms, legs and genitals swell to monstrous proportions - hence the name elephantiasis. More than 120 million people worldwide are infected with the pathogen wuchereria bancrofti.

Adult wuchereria worms have a lifespan of up to five years. During this time they produce millions of offspring, what are known as micro-filariae, each of them smaller than the full stop at the end of this sentence. If the host is bitten again by a mosquito, the micro-filariae are ingested together with the blood. Inside the insect they mature into infectious worm larvae, thereby completing the circle.

'Although the drugs currently in use kill the micro-filariae, they largely leave the adult worms unscathed,' Bonn parasitologist Professor Achim Hörauf explains. 'Due to the long lifespan of the wuchereria worms, therapy lasts several years, during which time the symptoms continue to persist.' What is more, the drugs may cause severe side-effects.


De-worming the roundabout way

Yet the threadworm, too, has a sub-tenant, and this may be its Achilles heel, since in each wuchereria worm there are specific bacteria which are absolutely indispensable to the parasite's survival. If these bacteria die, the parasite will also die sooner or later.  'This is why wuchereria is susceptible to antibiotics which are normally used against bacterial infections,' Professor Hörauf emphasises. One example is doxycyclin, which has been used for decades for infections of the respiratory tract and the gastro-intestinal tract.

In their study the medical experts in Tanzania treated 72 male patients for eight weeks with doxycyclin or a placebo. Initially the patients' blood was swarming with micro-filariae: the researchers counted up to 1,300 of them per millilitre of blood. Eight months later they had almost completely disappeared; only in one patient were sporadic micro-filariae still detected. However, the proportion of micro-filariae also dropped in the placebo group - an effect which was probably due to the improved
care given the test persons.

Unlike the drugs in use up to now the antibiotic also killed off the adult worms. Fourteen months after being treated with doxycyclin the doctors were only able to detect the typical movements of the worms ('the dance of the filariae') on ultrasound in one in five patients. In the placebo group the rate was 89%. In the doxycyclin group the concentration of specific worm proteins in the blood fell by over half.

 
Effective, cheap, few side-effects


'The importance of these findings for therapy should not be underestimated,' Professor Hörauf emphasises. 'The mature worms are after all responsible for such symptoms of the disease as the extreme swelling of the limbs. In the past there was no effective and reliable method of combating them.' The effectiveness of the antibiotic might be even greater than what was measured: 'We cannot exclude the possibility that several patients became re-infected in the months following treatment with doxycyclin. It is therefore quite possible that all the worms were killed and the remaining 20% are the result of re-infection which would no longer occur if infection was effectively prevented.

Doxycyclin has been used for many years and has only minor side-effects. However, in young children it may cause irreparable damage to the teeth and slow down growth of the bones. For this reason the antibiotic should not be used during pregnancy, either. For adolescents and adults, however, the drug is harmless. Moreover, it is comparatively cheap. 'Its biggest advantage is that it is already licensed for medical use,' Professor Hörauf points out. 'Elephantiasis hits the poor most of all. It is therefore not likely that the pharmaceuticals industry will develop completely new drugs.'

Male 35 (Hamburg-Germany),CFIDSi, IBSi, Enterovirus, Cpni,treated Enterovirus with Inf-y,Inf-a.,Ribavirin. Started Wheldon Capi on 02/19/08, Currently NACi 2400, Doxy 2x100, Biaxin 2x500, Metroi pulses,pyr

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Male 35 years (Hamburg-Germany),CFIDSi, IBSi, Enterovirus, Cpni for years positive. Started Capi on 02/19/08, Currently NACi 2400, Doxyi 2x100, azi 250, tinii pulses clarithromycin 2x500, metroi pulses, 12 g calcium pyruvat

I have been treated with

I have been treated with ivermectin - and noticed HUGE results... for starters i now have no allergies whatsoever - before i had hay fever type symptoms almost everyday - apparently a history of allergies can be a sign of roundworm infection.

 The worms Dr W treats are cryptostrogylus pulmoni - http://members.aol.com/SynergyHN/roundworm - i felt 'ME ill' before i took the ivermectin - now i am having huge porphyriai and herx symptoms - which i can only assume is die off as my immunei system is now working better. I have all the symptoms on somone on the CAPi without actually doing the antibioticsi.

 Dr W has just changed his protocol to include Doxyi - and he says it does have some worm fighting abilities - although they are not as powerfull as the ivermectin i think. Maybe prologned doxy would be enough to kill them off anyway.

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Paul UK.CFSii.CPni/Crypto/Bor. Ivermectin.May08.NAC1200mg.Doxy200mg.Azith250mg(MWF).Omeprazole40mg,Flagy pulses 800mg/

Thanks for sharing your

Thanks for sharing your experiences with this treatment. I want to keep following this post.

Louise, CFSi. CPnPositive. BbPositive. WheldonCAP began6/24/07. NACi,Doxyi, Roxi,FullTiniPulses. Intermittent Cholestyramine,1-2packets, at bedtime,most often with pulses,and as needed, for Phorphoria & liposacaride Endotoxini Die-OffExperiences.

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Louise  CFSi, CPN+/Bb+, Wheldon CAPi 6/07, Cholestyramine 1-2 pks @ HS for Porphoria & Endotoxinsi PRN, Doxy100daily, Roxi300BID, Tinii 500mgBID pulses, VitD3-4000IU, Magnascent Iodine,{S.O.D.3/QD[KAL Brand], +Pyruvate 3.75G +SAM-e For Energy support

I took three courses of

I took three courses of Ivermectin several months ago. The first dose I got die-off and felt horrible. The second dose I didn't feel so good. The next doses I felt nothing. I had some pills left over, so yesterday I took one. I felt nothing. I think the Ivermectin killed something and was worth adding to my combined antibiotic protocol. I was glad to read doxyi has such a wide range of action. Combined Antibiotic Protocol minocycline, azithromycin, metronidazolei for muscle pain, insomnia, interstitial cystitisi, sinus, disphonia, dry eyes, stiff neck, veins, thyroid, TMJ.

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Combined Antibiotic Protocol minocycline, azithromycin, metronidazolei for muscle pain, insomnia, interstitial cystitisi, sinus, disphonia, dry eyes, stiff neck, veins, thyroid, TMJ.

Hi ewokpd !  How did they

Hi ewokpd ! 

How did they found the c.pulmoni? Blood sample, sputum?

And how much ivermectin did you take? and for how long?

 

Regards Cesare  

 

 

Male 35 (Hamburg-Germany),CFIDSi, IBSi, Enterovirus, Cpni,treated Enterovirus with Inf-y,Inf-a.,Ribavirin. Started Wheldon Capi on 02/19/08, Currently NACi 2400, Doxyi 2x100, Biaxin 2x500, Metroi pulses,pyr

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Male 35 years (Hamburg-Germany),CFIDSi, IBSi, Enterovirus, Cpni for years positive. Started Capi on 02/19/08, Currently NACi 2400, Doxyi 2x100, azi 250, tinii pulses clarithromycin 2x500, metroi pulses, 12 g calcium pyruvat

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