Is there a best time to test for Cpn?

I know testing is very tricky. I was tested a couple of years ago, but it was whilst I was on antibioticsi for Lyme. IgGi and IgM were negative.

Now I am off antibiotics for 3+ months and my symptoms are persistant, with generalised inflammationi and feeling like I have upper and lower respiratory tract inflamed and infected but with no productive cough or nasal discharge.

 NAC test challenge provoked runny nose+++ and flu-like symptoms.

 So....would this be a good time to try and test again, or is it just not worth it?

If yes, would a PCRi test be a better way to go?

I am pretty sure my doctor would let me do the protocol, but I am the kind of person who likes a "piece of paper to prove it" if i am going to commit myself to another lengthy treatment.

 

I know I am asking for a lot ! 

Annelet, Several people here have found they tested positive for CPni after a few weeks on the protocol. (They had tested negative, or very low, before going on the protocol.) It seems logical, since the meds drive the bugs out of hiding (inside the cells) and make them 'visible' to the tests.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Annelet, I don't remember why you were on CAPi, perhaps MSi or CFSi/ME with that Lyme treatment?

It seems that there are differences between the diagnosis which I do admit are only based on what I have been reading for the past 4 years as people post here and an occasional person infact does get tested for CPNi with titers.

For myself, beginning to add Methylation support improved my general well being and continues to support my maintenance.  

I guess if you can afford the testing it may be a time after CAP that you could have some visable lab values.        

It used to be said here I am sure that you know that negative results can be false negatives.   So then if you got those again would you not go back on CAP even though you feel so poorly?   CAP restored my CD-57 to the normal range so it was effective for my Bb.

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

  These are my thoughts and what I do and have done that were good indicators I believe.  Quest labs seems to have a good test for Cpni antibodies.  I take the Cpn antibody panel for IgM, IgA and IgGi quarterly for several years.  For the most part from what I have read and is true with me are the antibodies show as follows: 

The IgM's elevate with the first exposure and then after several months are not detectable and they never return abnormal.  Many doctors are not use to seeing IgM's that never return even if infected as they use the IgM indicators to tell if you have an infection which is true for many bugs but not Cpn, one of its nasty little hiding tricks.

The IgA's and the IgG's elevate in several weeks to a month or two with the IgA's taking several months to reduce after the Cpn infection decreases and the IgG's up to several years.

Both IgA's and IgG's are good markers for a possible infection and especially so with both abnormal.  You may not find any abnormal levels and still have an infection though.

The PCRi test is the most accurate for a positive when it shows up but it rarely shows it is and a negative is very common even though there is Cpn present.  I have had Cpn at high levels without doubt and had a PCR nasal swab from Quest and a PCR blood test from Vanderbilt and both were negative.

Two common tests I would recommend and are inexpensive are first a Tetanus Antitoxoid that is frequently used with people that have an immunocompromised system to check there Th2 response.  Cpn frequently causes a Th1 / Th2 shift, I have that, and Tetanus Antitoxoid will hint that is so.  A typical value is 1 with higher then that hinting a shift towards a Th2 response. I believe the upper limit is 7 and I have been as high as 6.5 and after several years of CAPi for the first time it dipped to 3.5.

A Vitamin Di panel for levels in the blood and it will help you adjust your intake to where you want to be.  I started at less then 20 ng/mL and after 18 months have reached over 80 ng/mL.  Over 60 is somewhat critical I have read.  I will keep it between 80-100 ng/mL from now on.  Low levels of vitamin D are common with M.S. and Cpn infectionsi.  Test a second time only after three or four months as it takes a bit of time to see the correction.

Cpni, Mycoplasma, Chronic EBVi, M.S.(MRI, Spinal Tap-greater than 5 oligoclonal bands and VEP), PANDAS(OCD). Wheldon CAPi (started 12/08), Azithromycin/Clarithromycin(12/09), Lithium, Lamictal, NACi(2.4g/day), D3(15,000IU/day)

My IgGi titer was slightly positive after starting NACi (but before the antibiotics).  After two months on abxi, my IgG went up.  I was told that was not unusual because with the antibiotics knocking down the Cpni it gives the immunei system a chance to rally against it more effectively, thus causing higher titers.

Started CAPi for Cpni on 11/14/10 - Per my doctor, paused Abxi 5/18/13 - NACi, T3, St Johns Wort, B-complex, Vit C, Vit D3 (8,000/day), Vit E, Astragalus, Chlorella, Chelation with Alpha Lipoic Acid">i. Started Buhner protocal (2nd edition) on 8/30/16.

Thank you all for these comments.

My Vitamin Di is around 60 and I am still supplementing.

Could you tell me how much the 3 Ig's ( M,G and  A ) from Quest labs are?

I know my IGenex Lyme test became 'more' positive after I had been on abxi for a few months....so I can understand why the Cpni might be the same. 

Focus Diagnostics also offers a Cpni test: 

http://www.focusdx.com/focus/1-reference_laboratory/search_frame.asp?sea...<

I can't tell by looking at my insurance paperwork how much that test is (the insurance codes are different from the test codes, and I have a lot of labs run at the same time, so I don't know which code is for which test.)

Best, Timaca

on valtrex 500 mg tid

http://whispersfromthefather.me/<

 

 

 

Ask your doctor to test your Cpni titers.  My original tests were run through my local hospital and ordered by my local internist.  My second tests were done through Qwest.

You really don't need the tests after your NACi reation.  But I totally understand wanting them.  I am the same way.  Plus, it is easy to convince a doctor to treat you with the CAPi if you have a positive test.

Started CAPi for Cpni on 11/14/10 - Per my doctor, paused Abxi 5/18/13 - NACi, T3, St Johns Wort, B-complex, Vit C, Vit D3 (8,000/day), Vit E, Astragalus, Chlorella, Chelation with Alpha Lipoic Acid">i. Started Buhner protocal (2nd edition) on 8/30/16.

 The Cpni<i< titers can be useful to get some idea and assurance after time goes on that you are makng progress if they show abnormals.  They have been declining, the titers, with me after years of testing.  IgGi<i<'s are still very high but the IgA's have dropped two titers in about 24 months on CAPi<i<, NAC and vitamin Di<i<

  The test I take is the complete Cpn panel and I think it runs several hundred dollars, not sure though.  Blood test costs are very unpredictable as they contract at different rates through different health insurance carriers and then for walk-in cash.  Some of my tests are almost nothing in cost to my insurance company as they are fixed in by bulk contracts, funny money goes back and forth.  Call Quest and ask them if that is where you are going to go but your insurance bill will be different no doubt.

The test I track Cpn antibodies with is from Quest Labs:  7821

http://www.questdiagnostics.com/hcp/testmenu/jsp/showTestMenu.jsp?fn=7821.html&labCode=QSO<

Cpni, Mycoplasma, Chronic EBVi, M.S.(MRI, Spinal Tap-greater than 5 oligoclonal bands and VEP), PANDAS(OCD). Wheldon CAPi (started 12/08), Azithromycin/Clarithromycin(12/09), Lithium, Lamictal, NACi(2.4g/day), D3(15,000IU/day)

Thanks.....I will call Quest and get the price.

I live in Canada, but will have to go to Plattsburgh, NY for the test. There is a Quest lab there.

I will have to pay cash as this will not be covered by insurance. Should I tell the lab that up front? Do they quote a different price for a cash customer? 

In one statement, you ask if it is really worth testing.  You had a definite reaction from NACi.  In my mind, that is as good as, or better than, any test.  I was never tested so I am biased. 

Rica

3/9 Symptoms returning. Began 5 abxi protocol 5/9 Rifampin 600, Amox 1000, Doxyi 200, MWF Azith 250, flagyli 1000 daily. Began Sept 04 PPMSi EDSSi 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

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