Intermittent Protocol - Clarification please?

I seem to have 2 versions of the Intermittent Treatment and looking for clarification so I do this right. I have been on Capi for 22 months.

First one here seems to say that you do a couple of weeks and then off for a couple of months. Second one seems to say that you are on for two weeks a month.

1. When you move to the intermittent stage, you are STILL doing it the same way, except you will be taking the abxi<i< for a few weeks (pulsing metro a few days right in the middle), then be off all three of them for a couple of months, then be on all the abxi<i< for a couple of weeks (again pulsing metro right in the middle of that), then be off all three of them for a few months...  repeat as needed.

2. "The eventual aim is to give all three agents intermittently so that there is some respite from antibioticsi<. This, the final leg of treatment, may entail a 14 day course of doxycycline and roxithromycin, with a five day course of metronidazolei<i< in the middle. This course is given once a month. After several months the intervals between the antibiotics may be cautiously extended. Rifampicin is not suitable for intermittent use, and azithromycin may be given instead.

Thank you for any clarification as to how to proceed.....Linda
 

Comments

Thanks to all of you so very

Thanks to all of you so very much - I want to be very clear about what to do as I sure do not want a relapse. And, CAPi has indeed saved me so far! However, with my kidney/liver issues it seems the way to go to the intermittent. Will get back and thank you all again for the support on such a rocky road, as you all well know. I am on some herbals to fight this and other things so would be pleased to let you know what I am taking in case you wish to know. Linda

From Dr. Wheldon's site

"The eventual aim is to give all three agents intermittently so that there is some respite from antibioticsi. This, the final leg of treatment, may entail a 14 day course of doxycycline and roxithromycin, with a five day course of metronidazolei in the middle. This course is given once a month. After several months the intervals between the antibiotics may be cautiously extended. Rifampicin is not suitable for intermittent use, and azithromycin may be given instead."

http://www.davidwheldon.co.uk/msi-treatment1.html

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

Pulsing and/or Intermittent

here are my notes from this site on this subject, hope it helps

You can THINK ABOUT stopping<

Submitted by jen_obrien< on Thu, 2015-07-23 20:47.

You can THINK ABOUT stopping treatment when you are no longer experiencing die-off from the abxi<i<.

Experiencing die-off indicates that Cpni< are still present in the patient’s system and are being killed.  They need to continue the antibiotics til the die-off is almost non-existent. It may take 3 to 5 years.

The patient may think they are done with the CAPi<i< because they aren’t experiencing die-off….which couldn’t be more wrong. Cpn is sneaky and hides in cells. It’s best to continue with the protocol a little while longer, just in case, and then consider intermittent treatment.  This would entail cutting back the first 2 antibiotics (Doxyi<i< and Azith/Roxi) to a 14-day course, taken once a month. In the middle of those 14 days, the patient would insert a five-day course of the third antibiotic (Metroi</Tinii<i<).

When the patient feels they are Cpn-free, they can finally stop the antibiotics. BUT they need to make sure to keep taking the NACi<. They should probably take it for the rest of their lives. It will keep them from being re-infected. That is very important.

PULSING:

You should be on a pulse five days out of every 28 days.

Day 1-21 is two antibioticsi<.

Day 22-26 is all three antibiotics.  OR, day 23-27 is all three antibiotics.  OR, day 24 through 28 is all three antibiotics.

No one is going to hunt you down and chastise you if you pulse a day or two sooner, or start a week later.    A lot of this depends on how well you do - or don't - feel.  Basically, you're going to try to pulse five days a month

Intermittent treatment                           

Submitted by Sarah< on Thu, 2015-08-06 15:21.

My suggestion is that after two years of treatment you should have cleared the C pn.  To be sure you could go on intermittent protocol, but if you do, you will have to stop the rifampicin, so just carry on with the minocycline, azithromycin and flagyli<, taking mino and azith for two weeks once every two months, but adding the flagyl for five days at the end.

Like most people here, I ever took flagyl every day, but just pulsed it every month or so for five days, and I never took amoxicilln because you don't need it with NACi<: you have been too hard on yourself!.......................Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MSi< in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

After your year on combined<

Submitted by Alfy87< on Thu, 2015-09-17 16:23.

After your year on combined therapy you may want to do a maintenance schedule. My asthmai< came back even after a year of treatment. I should have done 15 days every 2 months for a couple years more. This bug is tough and does not give up easy.. I am back on therapy and after 4 months doing much better.. but I will have to repeat a year once again.

 don't remember ever saying

 don't remember ever saying this:

Day 1-21 is two antibioticsi<i<.

Day 22-26 is all three antibiotics.  OR, day 23-27 is all three antibiotics.  OR, day 24 through 28 is all three antibiotics.

I would never describe it like this.

Jen, that sounds more like me

Jen, that sounds more like me than like you.  (A way of getting the idea across that the patient should take ALL three antibioticsi together for five days out of every twenty-eight days.  Definitely not a description of intermittent treatment, though.)

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi