How to Take B12 Methylcobalamin Lozenges?

We have the above lozenges and wonder how best to take them.  Paula has a terrible problem with constantly producing clear mucas down the back of her throat, which she needs to spit out every few seconds.  (Possibly caused by her Samento).

This causes a problem when trying to dissolve the B12 under her tongue (ie, she is spitting some of the dissolved B12 into her paper towel)

On the B12 bottle it suggests either dissolving under the tongue or chewing the lozenges.  If she chewed the lozenges, how long should she wait before swallowing them (hopefully this would be in-between coughing up her mucas)?

How long does it take for the B12 to enter the blood stream?

Would chewing work as well as dissolving under tongue?

We would rather not go down the B12 injection route, so what does everyone suggest?

 Many thanks,

Mark.

Carer. Bedridden severe ME/CFS Feb06. CPNi dxi. Apr07. Samento 15xper day.  Building up on Supp. before CAPi.

UK Carer of bedridden Severe CFS Feb06. Tick bites Summer04.  CPNi dxi.Apr07. Borrelia dx Sept08. Samento 15 drps daily July07.  200mg Doxyi Jan08.  300mg Roxy Apr08 Stopped abxi Nov/Dec08. Building up on Supps again.

B12 only needs to be absorbed before it hits the stomach, so chewing and then letting the stuff further dissolve anywhere in the mouth until it has to be swallowed will be fine.  That is how I always did and still do it.........Sarah    An Itinerary in Light and Shadow   Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still slowly improving and no exacerbation since starting. EDSSi was 7, now 2, less on a good day.
Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

Thanks Sarah,

The problem is that Paula is continually (every few seconds) spitting out mucas into her paper tissue, so this means that some B12 residue is also spat out.

I noticed this in an earlier post by you :-

"You just need to suck the lozenges, or munch them up and swallow the small particles.  If they are absorbed anywhere before they hit the stomach, the effect will be the same, according to DW.  I used to laboriously suck them and take an extra one if I accidentally swallowed one, now I save money by not bothering........Sarah"

Paula's problem is her continous need to spit out, so is it a bit like sucking a sweet and swallowing the saliava, but leaving the tablet in your mouth, or should she mulsh it then swallow tablet? How long would she need to mulch the tablet before swallowing it and absorbing enough B12?

 Sorry for all these questions, but it does get a bit complicated all this cpni stuff Frown 

Carer. Bedridden severe ME/CFS Feb06. CPN dxi. Apr07. Samento 15xper day.  Building up on Supp. before CAPi.

UK Carer of bedridden Severe CFS Feb06. Tick bites Summer04.  CPNi dxi.Apr07. Borrelia dx Sept08. Samento 15 drps daily July07.  200mg Doxyi Jan08.  300mg Roxy Apr08 Stopped abxi Nov/Dec08. Building up on Supps again.

Could you melt the lozenge in a tablespoon of warm water and take it that way, sipping a little of the liquid and holding in the mouth for a few seconds?   I'm not sure if the water would denature the V B12, but if it is done in a short period of time I imagine it would be OK.

Michele (UK) GFAi: Wheldon CAPi 1st May 2006. Daily Doxyi, Azi MWF, metroi pulse. Zoo keeper for Ella, RRMSi, At worse EDSSi 9, 3 months later 7 now 5.5 Wheldon CAP 16th March 2006

Michèle (UK) GFAi: Wheldon CAPi 1st May 2006. Daily Doxyi, Azi MWF, metroi pulse.

 There is also a spray http://www.evitamins.com/product.asp?pid=341 which is the Methylcobalamin form, or regular cyanocobalamin http://shop.1asecure.com/prod.cfm?ProdID=172247&StID=3117 as examples. This might be the most efficient way for her. A spray here, a spray there...

CAPi for Chlamydia pneumonia since 11/04. 25yrs CFSi & FMSi- Currently: 200 Doxycycline, 500mg MWF Azithromycin, Tinii pulses.

A motto, not an aspiration: "Anything worth doing is worth overdoing."

 

CAPi for Cpni 11/04. Dxi: 25+yrs CFSi & FMSi. Currently: 250 aithromycin mwf, doxycycline 100mg BIDi, restarted Tinii pulses; Vit D2000 units, T4 & T3, 6mg Iodoral

Hi Mark and Paula, I often place the lozenger along the upper border of my upper teeth and cheek and try to keep my tongue away from it particularly because it is generally so good tasting.  It could be possible to spit out the mucous and still retain the Loz for absorption by the buccal mucosa.  I find under the tongue to be a location that is harder to ignore.  And you want to ignore it got for as long as possible so that it can be absorbed by the mucous membrane.   I had not heard of the spray option until now.

Louise

CFSi. CPni posititve, Bb positive. Started CAPi 6/24/07  Doxyi and NACi 11/3/07 Macrolide 150mgBID added to Doxy100mgBID,NAC600mgBID 11/22/07 added #1 Tini Full 5 day pulse 500mg BID, porphoria and Lipo Endotoxini sxs, to start Cholyst ASAP.

  • CAPi(TiniOnly): 06/07-02/09 for CFSi
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support

Thanks for these links, Jim. Wish I had had them before I had my compounding pharmacy mix up a batch of the methylcobalamin nasal spray for me--at the cost $80.00 USD!

Am also wondering...are all of the solutions a bright red color? I hate using it and then worrying about what it might stain when it drips back out, or if I sneeze, etc.

--Minai

RRMSi, diagnosed 2/04. NACi 4/06. Started Wheldon/Stratton regime 8/30/06. Doxycycline, 8/06, Azith, 10/06. Switched to Roxithromycin 11/06. Psuedo relapse/die-off with hospitalization 1/07. Gad-enhanced MRI of brain and spine shows NO NEW DISEASE ACTIVITY Restarted CAPi with NAC and Doxy 2/07. LDNi 4/07. Stopped NAC, started Roxi, again 5/07. Now on full doses of Doxy and Roxi. NAC, again, 7/07. 1st Tinidazole Pulse, 8/11/07. USA

Hi,

 Thanks everyone for your help.  We are sticking with the lozenges as Paula has times when she doesn't need to spit out so much, so will take them at that time.

Thanks Jim, but I think we will persevere with the lozenges.

Thanks Louise, I think we will give that a try.

All you guys are the best.

Smile

Mark

Carer. Bedridden severe ME/CFS Feb06. CPNi dxi. Apr07. Samento 15xper day.  Building up on Supp. before CAPi.

UK Carer of bedridden Severe CFS Feb06. Tick bites Summer04.  CPNi dxi.Apr07. Borrelia dx Sept08. Samento 15 drps daily July07.  200mg Doxyi Jan08.  300mg Roxy Apr08 Stopped abxi Nov/Dec08. Building up on Supps again.

Hi,

Paula's production of mucas has subsided by about 80% over the past two days which means she has had no problem taking the B12 losenges.

Lets hope it lasts as she took her last Ivermectin tablet 2 1/2 weeks ago. 

Carer. Bedridden severe ME/CFS Feb06. CPNi dxi. Apr07. Samento 15xper day.  Building up on Supp. before CAPi.

UK Carer of bedridden Severe CFS Feb06. Tick bites Summer04.  CPNi dxi.Apr07. Borrelia dx Sept08. Samento 15 drps daily July07.  200mg Doxyi Jan08.  300mg Roxy Apr08 Stopped abxi Nov/Dec08. Building up on Supps again.

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