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Friedman, Yamamoto, Bendinelli: Cpn - Infection and DiseaseSubmitted by AndreasHH on Thu, 2008-07-10 09:36.Hi everybody, this book is a compilation of articles on cpni, published in 2004: http://www.amazon.de/gp/product/0306484870/ref=sib_rdr_dp Does anybody happen to know this book? Is it still worth reading being 4 years old? Greez Andreas ___________________________________________________________ »
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I don't know this book and
I don't know this book and from reading the blurb I probably would not as is looks to me like a scientific book.
A book I did read that does not cost as much is 'the Potbelly syndrome' By Russ Farris. Very well written, easy to understand, good diagrams and pictures. Written by a sufferer...
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Michèle (UK) GFAi: Wheldon CAPi 1st May 2006. Daily Doxyi, Azi MWF, metroi pulse. Zoo keeper for Ella, RRMSi, At worse EDSSi 9, 3 months later 7 now 5.5 Wheldon CAP 16th March 2006
I have that book - its a
I have that book - its a good scientific introduction to chlamydia pneumoniae. It relates cpni infection to a whole host of serious chronic illnesses. So it would be a great book for e.g. showing a doc that this is a serious infection.
The downside is that because it is scientific, a lot of the text concerns intricate biological details which are not clinically relevant. So you probably wouldn't get much in the way of take-home information from a treatment point of view.
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Hunter: Don't think - experiment
@ garcia:What does it say
@ garcia:
What does it say on vaccines? Is it possible to get an immunization - after successfully having completed the therapy by antibioticsi, or maybe even getting clean from cpni by autovaccines (as a therapy itself)?
Greez
Andreas
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What can't kill us will leave us even stronger. (Nietzsche)
Andreas, there isn't a
Andreas, there isn't a commercial human vaccine available at this point in time, so its not possible to get vaccinated yet. Whether treating a current infection induces immunity from further infection is an interesting issue.
The book has a good article on Cpni Vaccines. On the subject of conferring immunity the authors state: "studies in an experimental model of infection with Ctr indicate a short-lived immunity after natural infection."
There are some major issues to be overcome if a vaccine is to be developed though. One issue is that the same antigens (e.g. Hsp60 & OMP-2) can both lead to increased protection or increased susceptibility depending on the vaccine adjuvant used (some adjuvants encourage a Th2 response which leads to increased susceptibility).
The authors state that "A major challenge here is to produce a strong Th1 response conferring protection without immunopathology."
They also go on to say that: "However, immunity after a natural C. Pnumoniae infection is not completely protective."
On balance it seems then that infection will confer some immunity to the host, but that this is by no means perfect.
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Hunter: Don't think - experiment