Elevated myoglobin, could it be porphyria?

I was curiouse to know if an elevated myoglobin could be an indication of prophyria?

Has anyone else experiernced this with blood lab results? 

 

Thanks for any information on this topic.

Hi Bonnie,   I just googled, here is an NIH link regarding serum myoglobin elevations.   Louise

http://www.nlm.nih.gov/medlineplus/ency/article/003663.htm<

This link  above does contains a list of conditions associated with serum myoglobin elevations, as Jeanneroz has highlighted them below in her post.

I'll will see what else I can find. 

Was there a profile of tests drawn at the same time or was this an individual test?     

What I see is that creatine converts to creatinine as some aspect of the methylation cycle.

My take is that it is not directly related to porphyriai but could be related to deficient methylation activity. 

The bio chemistry currently is elusive to me but I see the creatine to creatinine shift in Dr AY's diagram and recall that she finds creatinine elevate in some of her patients due to some set of imbalances.      

So that is probably as clear as mud and about all that I can say is don't chalk it up to porphyria at this point until your doctor gives you some perspective.  

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

Hi, bonnie,

I doubt if it is porphyriai, per se.   Considering the fact you are having extreme muscle pain and such, do you think perhaps it could be myositis?  Myositis: "Myositis is an inflammationi or swelling of the muscles, often caused by injury, infection, or an autoimmune disorder.  And it is listed as one possible reason for elevated myoglobin.    It wouldn't appear you have the other illnesses related to abnormal results but  I'm not a doctor.  Did your doctor give you any input on this? 

 I've not seen anyone else post about this on the site... 

What Abnormal Results Mean

Greater-than-normal levels (a "positive" result) may indicate:

JeanneRoz

 

JeanneRoz ~ DXi'd w/ CPNi 4/2007; 6/07 -"officially" dx'd w/CFIDSi/FM; also: HHV6, EBVi, IBSi-C, 100 Doxyi:BIDi<; 500 mg Biaxin BIDi; Tindamax Pulses, B12 shots, ERFA Dessicated Thyroid,Cortef, Iodoral 25 mg, Vit D-6,000 uni

Thank you for the responces. I am leaning towards the possibility of skeletal muscle ischemia, as the cpni is known to be vascular in nature, and I have had many hypercoagulation issues during my treatment. I found a interesting article on coagulation regulatory defect. It mentions with infammation the blood can become thicker and this can cause more mircrobes within the blood to create a anarobic environment. Dr. P has me on more omega 3, up to 6-9  caps per day. I also am taking Lambrokinase and Nattokinase. This is a welll known symptom with possible heavy metals.

I am looking into the methylation test for myself. It is a major breakthough for many chronic illnesses, and adjunt for treatment.

 

 

Bonnie

started Wheldon capi 4/21/08 for Cpni, CMV, EBVi, CFSi. Cap hold 4/09vascultis. Restart 9/09 with Dr.Powell, restore gut, 4000 D3, supplementsi,  Pos. Bartonella and Babesia, Rifampin 600 mgs and Biaxon 1 gram. 

Bonnie, Was there a profile of tests drawn at the same time or was this an individual test and what related previous tests have there been?     

What I see is that creatine converts to creatinine as some aspect of the methylation cycle, do you have any labs that show either of these to be out of range on lab tests?

As I said above, my take is that it is as you suggest inflammationi but not directly related to porphyriai<i.  And it is worth considering the possibility that it could be reduced when any related deficiencies in methylation activity which could contribute pieces to the missing puzzle pieces to re-establish balance and which could be ultimately  by passed with the proper supplementations. 

We are all such works in progress.    Louise

  • CAPi(TiniOnly): 06/07-02/09 for CFSi<
  • MethylationProtocolSupplements: Started08/08
  • Intermtnt CAP: 02/09-02/10
  • Full MethylProtocol & LDNi 02/09
  • Off CAP: 02/10, cont LDN & MethlyProtocol support
  • <

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