Does vit C enanche replication of chlamydia?

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Comments

Hey PaulJ, I would rather

Hey PaulJ,

I would rather concede myself than take 100 grams of Vitamin C orally ;) But there are people who do this and some on this site take "moderate doses", probably in the 5-20 gram level. Anyway I am just arguing here. I actually agree with you that Vitamin C is of dubious value.

- Paul

OK, I'll concede, if you can

OK, I'll concede, if you can take 100 gm at a single dose you should be able to reach those levels in at least some parts of the body.
Blogger at http://perfecthealthdiet.com<. 17-year chronic illness cured with diet and antibioticsi, nearly fully recovered.

Hi PaulJ, I hate to pull a

Hi PaulJ,

I hate to pull a Norman and argue every tedious point but...

such levels aren’t physiologically attainable in the human body

What would make you think that? People take up to 100 grams orally. What do you think the Vitamin C levels are in the cells in the stomach and intestines when they do this? I have personally tried 40 grams infused over an hour a few times. I am not an advocate of either of these approaches as I think they are interesting but mostly ineffective but I do think high levels are achievable in vivo.

- Paul

(Norman, hopefully you will take this with the intended humor.)

Paul –  Here are the only

Paul –  Here are the only two published papers on vitamin C effect on Chlamydia in culture:  
http://www.ncbi.nlm.nih.gov/pubmed/11938727<The results suggested that vitC was a kind of nutrient needed for CT. The proliferation of CT in the cell can be promoted by vitC.
  http://www.ncbi.nlm.nih.gov/pubmed/1400952<We investigated the effects of vitamin C on the growth of C. trachomatis E/UW-5/Cx in a primary culture of human amniotic epithelial cells. The results showed that vitamin C enhances C. trachomatis infection at concentrations of 0.2, 0.6, and 1.2 mg/dl (P less than 0.001). These three concentrations represent the in vivo concentrations of deficiency, normal, and overload levels in serum, respectively. The enhancement was dose dependent. However, the growth of C. trachomatis was inhibited at vitamin C concentrations of 120 and 1,200 mg/dl.  
So you have to get up to 200 times normal cellular levels of vitamin C before it starts inhibiting C. trachomatis growth … such levels aren’t physiologically attainable in the human body.  At all cellular levels achievable in vivo, vitamin C enhances C. trachomatis growth.  Presumably it does the same for C. pneumoniae. 
Of course, the main point stands – that vitamin C is probably helpful for C. pn. patients since it benefits the immunei response and normal cellular function.
Blogger at http://perfecthealthdiet.com<. 17-year chronic illness cured with diet and antibioticsi, nearly fully recovered.

thank's paul, i ll take it 2

thank's paul, i ll take it 2 gr. per day..

 Dome

PaulJ, That is not

PaulJ,

That is not correct. Vitamin C both promotes and inhibits Cpni in a dose dependent manner. Reading between the lines suggests that it induces Cpn into an EBi state which can have both effects depending upon how many of the Cpn in a cell are induced. In any event it does not do a great job of this as it has very short (30 minute) half life so it is basically exiting your system as quickly as you ingest it.

- Paul

Vitamin C does promote

Vitamin C does promote Chlamydia growth in the test tube ... However, it is also important for immunei function and Chlamydia defense in vivo.  I have a chronic infection which may or may not be CPni, though it behaves just like it.  I developed scurvy when my infection was at its peak and that was the low ebb of my disease.  Since I began supplementing with vitamin C, I have been improving (also improved other things at the same time, I'm not attributing the improvement to vitamin C).  I believe the bacteria use and deplete the body's vitamin C, which leads to glutathione depletion and impairment of the immune response, as well as the potential for scurvy, which can be devastating.  You're much better off supplementing with vitamin C is my view. 
Blogger at http://perfecthealthdiet.com<. 17-year chronic illness cured with diet and antibioticsi, nearly fully recovered.

Need info on what would be

Need info on what would be the test to have for chlamydia to give to the doctor.  I tried to do a search but could not find what I seen at one time.  Is there anything else I could bring my doctor to convince her about treatment or other things on this bacteria.  Thank you chipper

CFSi,COPD, asthmai,IBSi, no abs, looking for Doc,vitaminsi, NACi,1200 dy, alpha lopic, iodine 50mg.

 

Chipper,Here's a link to the

Chipper,

Here's a link to the original version of my notebook: http://www.thisisms.com/ftopic-4375-days0-orderasc-15.html< 

You need to go down a few posts to find the one about the notebook.  I'm sure that there are recent articles you might want to add, but this is a start.

Given that, we had a tough time finding a doctor and eventually went directly to Vanderbilt.  But, if Vanderbilt hadn't been an option, I think our best local bet would have been to find a local doctor that knows about Lyme.

Finding a doctor was harder than we expected. Good Luck, Ken

 

In pursuit of ABX<

Don't Allow What You Know To Get In The Way Of What Might Be

any new info about

any new info about intravenous c and cpni/ctri?

i took IV c 7.5g on tuesday and it knocked me down. fever and total sceletonal muscle weaknes.

i read in those articles, vit c helps chlamydial inclusions. it also states 120mg/dl and more acrobic acid inhibits chlamidial inclusions. is 7.5 g of vit c about 150mg/dl? if so, high dosesof vit c shoudl be anti chlamidial?

On CAPi from 03/14. CPNi/CTRi.