Tinidazole

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Anti-bacterial agent used to kill the cryptic form of Cpn. An alternative to flagyl (metronidazole).

Flagyl/Metronidazole v/s Tindamax/Tinidazole - Info Hub

Kim's just starting her December 2009 pulse and she's "Out the Gate Early".  Meaning, Flagyl "fun" started up on day-1 of the pulse.  I've read that folks on Tinii have less of this and I came here today to think about it.  First here's a couple links to RxList:

Flagyl (Metronidazole)< and Tindamax (Tinidazole)<

I thought it was interesting that both of them had peripheral neuropathy listed as side effects.

Being a good cpnhelp'er I did a search and here are links I found:

Driving and Cooking While Pulsing Not Good

The day before Thanksgiving and I was rushing around gathering food to take to my Mom's house. I made too tight a turn in the parking lot, ran over the curb and blew out one of my tires. Looking back, I was probably a little dingy from the 4th day of Tini.

Later in the day I was making pie shells and put them in the oven to bake a bit before I poured in the pumpkin filling. I was looking for some dry beans to weight the crust but only found some rice. I poured the rice in the shell and put them in the oven. When I took them out I found the rice had sunk into the pie crust and I had to dig all of it out. Well, I got most of the rice out but some is still stuck in the crust. The pies were very good in spite of this--just have to pick a few hard kernels out.

I did something crazy

After reading this website...

http://onthepharm.net/2007/08/flagyl-alcohol-reaction.html/<

...I decided to take a chance and have a glass of wine on my second day of a tini pulse. I had no negative reaction whatsoever, other than the anxiety of worrying about what might happen!

Next morning I was still fine. On the third night of taking tini I had 2 glasses of wine. Still no bad reaction.

In fact, in stark contrast to flagyl, which causes me severe depression, I've actually been in a particularly good mood these last 2 days. Is it possible that tini+alcohol could actually have a positive effect on those who don't get violently ill from it?

OT: MS/Lyme - safe to use Fasigyn (1g) for 15 days?

Hello ,im new to the site :)

My story:

I was diagnosed with MSi in 2002, and i recently read how lyme disease can mimic MS, and after getting alot worse on LDNi (which makes MS patients stop progressing) made me realise i could have been misdiagnosed.

So earlier this year had a Lyme disease blood test - Lymphocyte Transformation test, which came back positive, showing two different strains of Borrelia - Garinii and Sensu stricto.

 Ive been using a rife ,achine - 'Doug Coil machine' for the past 5 months, but haven't had a herx reaction, which shows NO spirochetes are being killed, and as the rife machine can only kill spirochetes, i now need to attack the hidden/dormant cyst forms of the infection.

Time to drop the big bomb,Tindamax

Hello to all on CAPi, It has been a while since I have posted. I have been on the CAP since late Dec. 08 and I have to say it has not been easy,but when faced with the fear of Alzheimers I find that I am highly motivated to stick with it. I took my first Tindamax today and it was really scary,especially after reading everything about the bad reactions, but I figure I really want to break thru to the other side! Lately I have had much pain in my head, especially in the front and very bad eye sensitivity. I am hoping the addition of Tindamax will help me. I also have been having what I think is reflux and post nasal drip. I have increased my yogurt and vitamin c intake. I will let you know of my progress and will try to do as many days as I can of the pulse.

Switching from flagyl to tini ... anything I should know?

I'm overdue for a pulse because my last couple flagyli pulses were so bad I needed a break. My doc and I decided we should give Tindamax a try. Now I'm trying to get up the nerve to try it but am hesitant. Anyone want to share their tini experiences or offer advice on any of tini's quirky effects I should watch out for (such as flagyl's alcohol issue)?

Trying to switch to Tini, but ...

Well, I finally completed another full Flagyl pulse on July 10, and I'm ready to pulse again in two days.  The last Flagyl pulse was very difficult on my digestive system no matter what I tried to do to help.  I had lots of pain, bloating, gas, all that fun stuff.  It also didn't go away very quickly after I finished the pulse, although I'm pretty much back to normal now.  I used charcoal, extra probiotics, glucose, Emergen-C with no relief. 

Is this a reaction?

My body is so sore???  It seems (to me) that it has been such a long time of 'poping pills' without results.   However, maybe I have had some; I seriously do not know.  I have been a little sore in my shoulder/neck area for about a year; 
I would only notice it when my big brother would give me a big hug (which he doesn't do anymore since I yelped at his big squeeze).  I changed from Flagyli to Tinidazole at my last pulse, which concluded three days ago.  The last few days I have been EXCEEDINGLY sore in this area.  I never thought this could be a reaction until this mornng, thus this blog.  Oh, I occasionlly get sore-to-the-touch on my skull; this has been going on a long time, I don't remember how long.  Would like input on this.   

Tinidazole Pulse Progress

Tinidazole Pulses. (Note: Latest entry at the bottom of page)

3.2.09 - 1 - 500 mg tablet

3.16.09 - 1 - 500 mg tablet

The reason I took one 500 mg tablet 14 days after the first tablet is that most of the reactions from it seemed to be gone so I thought, why not? I am in the process of ramping up to a full pulse so I am taking liberty to change things a bit for my benefit. Speed things up when I can as I am such a slow poke.

Switched to Tini for 4th pulse

Just completed my 4th pulse. Switched to Tiniazole instead of Flagyli. This time managed to get through the whole 5 days with no major hiccups! The only side effects I noticed were;

- slightly swollen glands (which always seem to appear when I start a new antibiotic - hopefully a die off reaction)

- minor nausea and headache on day 2-4

- feeling a bit down - I read that depression can be a side effect of taking Tini. Has anyone else experienced this? (although it could also just be the week of miserable, wet weather Sydneys been through!)

CAP & Adjunct Treatment update March 11, 2009

Treatment Overview on March 11, 2009;

Diagnostic Evaluation May 24, 2007. Chronic Fatigue Sydrome - Progressive onset - 20 to 30 years to overwhelming fatigue, Fibromyalgiai, Mild Form.  C.Pn. positive by Lab test result > 1:512,  Bb positive by Lab test Western Blot after doxycycline taken for 3 -4 weeks for CPni, Borrelia Burgdorferi (Lyme Disease) was revealed as positve on Western Blot late July 2007.

Started CAProtocol 6-21-07 with Doxycycline, N-A-C and all supplementsi<,  CAP Progressed on 10-31-07 Macrolide-added, progressed 11-22-07 Tinidazole-added and also Cholestyramine HS PRN x 7d starting day 3 - 4 of pulse and continuing for +/- 7 days.

Intermittant Protocol

Intermittant Thereapy~~~ There recently have been quite a few who have gone to intermittant therapy (hurray!).  I know in recent discussions comments are made "to refer back to their individual posts" to see what that consists of.  It is difficult sometimes to query this site for such specific information re each member.  

Metronidazole(Flagyl) comparison to TInidazole(Tindamax)

 Chanced upon this older thread started in June2006  I am bumping it up; http://www.cpnhelp.org/flagylvstinidazole< for reference and the original thread in context.

I am extracting a post that is very interesting to me and my situation.  Hope that some others may find it an interesting read as well.  Louise

 

Backsliding...

I am in a quandry.  I am concerned I may be developing a resistance to doxyi and/or azith, is that possible? Or could it just be time for me to mix it up?

 I am again very ill with severe bronchitis and/or cpni pneumoniae symptoms.  I am almost physically at the point I was in March of 2007 when I was first diagnosed (bed ridden, chest pain, deep bronchial coughing, very weak)  This is about the 3rd episode over the last 6 months (2nd within the past 2 months!)

In all honesty my improvements over the past year haven't been significant, other than a reduction in brain fog and a reduction in my FM symptoms.  As each month passes I keep adding to the mix..... I KNOW that is part of this process -- it just becomes more obvious how infected I must be.

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