Cpnhelp.org - Chlamydia Pneumoniae Treatment

Clammed - to my knowledge 3rd generation cephs such as Rocephini/ceftriaxone do not have activity against gram negative intracellulari pathogens such as chlamydia or mycoplasma, legionella, etc...

Here is the PI for Rochephin - pages 4 and 5 has the antibiotic sensitivity testing results. 

http://www.rocheusa.com/products/rocephin/pi.pdf

 Also from the Rocephin PI see lines 258 on  bottom of page 9- regarding Chlamydia trach in PID .

Also - Dr. Stratton does not reference any testing on CPNi with cephalosporins in his patent.

Based on mechanism of action of cephs it would make sense to me that they would not work in CPn.

Hope this helps.

^{Daisy - Husband on CAPi 5/07.   Roxy, Diflucan round three 4-4, Rifampin, Bactrim DS, Mepron 4-6, Prednisone, Novantrone, Doxyi, Azithromycin, Flagyli, Minoi}

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Daisy - Husband on CAPi 5/07.  "When Going Thru Hell, Just Keep Going", Winston Churchill

Daisy you are a good woman! Thank you soo much. This is eactly what I was looking for. I sense you see where Im going with this.

Minai 2 questioons is thats ok?

Have you ever taken penacillin, amoxicillini or ampicillin and if you havnt... are you penacillin allerrgic?

When you took the keflex and rocephini were you still on the capi bacteriostatics as well or diod you go off them?

Thanks both of you ~

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CPNi pcri and antibody positive , treating MSi, CFSi, TMJ, trigeminal neuralgia, IBSi neutropenia, pus found in facial bone, Doxyi 100x2,Doxy 200x2 zithro 250x1 alternate days. Metroi pulses each month.

Hi Clammed,

No. Am not allergic. I took Penicillin years ago with no problems. Have been taking Doxyi and Roxy (both macrolides) for over a year and a half with no problems, either.

 Yes. Was still on CAPi when I took the Keflex and Rocephini. Have been off all ABXi temporarily for over a month, until I stop suffering from the neuropathy so badly. Just started drinking Bentonite clay to soak up some of the endotoxinsi and it is definitely helping, so far.

Here is something that was just sent to me about Ceftriaxone(Rocephin) kiling both gram negative and positive bacteria in cases of pneumonia: LINK

--Minai

P.S. Would definitely heed what Michele and others say about which meds and how much to be taking. Straying from the protocol is what caused my problems

P.P.S. Had the same exp with an ER doc. Think it's because they know that they are isolated by ER work in not being held accountable in treating patients long-term. They're actually nice because of it

Minai - Good article on pneumonia.    Still don't believe that cephalosporins work for Cpni though. 

It is true that cephalosporins will work on some gram negative bacteria but they are not believed to work on the gram negative intracellulari ones like mycoplasma, CPn and legionella for example. 

Here's quote from study you linked "Concomitant treatment with erythromycin or metronidazolei was allowed when infection with Legionella pneumophila, Mycoplasma pneumoniae, Chlamydia pneumoniae, or a cephalosporin-resistant anaerobic organism was suspected."

Usually in a hospital setting where they are giving IV 3rd generation cephs for someone with pneumonia they will also add a quinolone or macrolide to cover the gram neg intracellulars.

Same is true in outpatient setting.  I have seen many doctors give a IM shot of Rocephini in the office and then prescribe a round of macrolides to go home on.

I am thinking your severe reaction to the recent IV cephs (and hope you are feeling better and better everyday!) was a die off of something else besides CPn.

^{Daisy - Husband on CAPi 5/07.   Roxy, Diflucan round three 4-4, Rifampin, Bactrim DS, Mepron 4-6, Prednisone, Novantrone, Doxyi, Azithromycin, Flagyl, Minoi}

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Daisy - Husband on CAPi 5/07.  "When Going Thru Hell, Just Keep Going", Winston Churchill