Would someone please advise what is a safe dose of biotin to take in one dose?   Is it also necessary to take magnesium with this?

Many thanks.


Hi Jam!

In the French experiment / trial, I believe that the bulk of patients were being given 300 mg in two doses. Some patients were given doses up to 600 mg. I make my own capsules, so weights vary greatly. I take a capsule containing 200 mg earlier in the day and then later take a capsule containing 130 mg much later on.

As yet, I personally have felt no improvement although I have yet to wake up dead. I do know a lady that I do believe that has regained bladder control due to biotin.

I have no knowledge of any relationship between magnesium and biotin.


“Don't believe everything you read on the internet.”

―    Abraham Lincoln<

On most of the mainstream biotin sites, they're suggesting 30mg a day.  Obviously, we're dealing with a specific health issue here, which might need a much higher dose, like what supaguy is talking about.  Once I hit 40mg, I start having bizarre dreams, so I'm staying at 30-40 for a good long while.

The difference between what we do and what we are capable of doing would suffice to solve most of the world’s problems. Mohandas Gandhi

I can take 150mg in one go, but any more and I can get palpitations for a while at night.  It never lasts long but it worries me when it happens, because things always seem worse at night....................Sarah

Completed Stratton/Wheldon regime for aggressive secondary progressive MSi in June 2007, after four years, three of which intermittent.   Still improving bit by bit and no relapses since finishing treatment.

HI there,

When do you take biotin?  With your antibioticsi?  With your supplementsi?  Does it matter when you take it?


I take it 2x a day in morning about 11am and again late pm/early evening before my evening antis.  I have no idea if this is correct.  I am off to sleep quite early and this fits into my regime.  Each capsule is 75mg, so 75 x 6 for me for the day.  SuperGuy may advise you differently, but he does fill his own capsules.  You could start on a little less to start as I initially did and then build up.  

Good luck!!!


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