Antifungals and probiotics

Antifungals and probiotics

Caution: most of the information collected here originates from manufacturers so please consider your options carefully.  

Some comments have come from users of these products, but as we know from our experiences with other medication each of us is different and may react differently to these products too.




Mode of Action


Acidophilus and other “good” intestinal flora

See recommended dosage by manufacturer.

Replaces intestinal flora killed by antibioticsi and/or imbalanced by Cpni, Candida, etc.

Helps prevents C. Difficile infection from antibiotics.

Best is a multi-flora formulation.

Enteric coated may help better survive stomach acids.

Essential when using CAPi’s

Calendula oil

Apply locally




2 x 2 daily

Fibre digesting enzymes eat candida cell walls

Not cheap. Does not need refrigeration

Caprylic acid

Up to 1500mg daily

Based on Coconut oil

antifungal antiviral

Can irritate sensitive GI mucous membranes



500 to 1500mg daily

Anti-inflammatory antifungal




200mg 2-3 times per week

by prescription


Uses p450 liver enzymes for metabolism, so caution if liver is affected.


Administrated intravenously by prescription

Antifungal interferes with candida cell walls

For systemic life threatening infectionsi.

Grapefruit seed extract

Between meals 125mg x 2 daily


Disrupts fungal cell membranes

Reasonably priced


1 cap x2 daily

Herbal antifungal

Not cheap



250mg daily or as directed

prescription only

Antifungal works by interfering with fungal cell walls

Can affect liver function

N-acetyl cysteine


Possible Antifungal action

N-acetyl cysteine may discourage colonization with Candida albicans


As prescribed by doctor

Antymycotic, antifungal affecting fungal cell walls

Allow lozenges to dissolve in the mouth.

Olive leaf extract

1-2 caps twice a day

Anti-viral, anti-candidal, antibacterial.

Stimulates NK cell production, so is immunei boosting

Oregano oil

Also in capsules

As directed

450mg x2

Antifungal, anticandidal, antiviral

Can be used as preventative or treatment of intestinal candida.   Cheap

Pangamin Bifi Plus

4tbl 2-3x daily

bifidobacteria and lactobacilli, saccharomyces cerevisiae

Cheap, available in Czech Republic or internet.

Probiotic Defense."

Now Foods

1x3 daily

Probiotic Homeostatic Soil Organisms

Not cheap

Saccharomyces boulardii

150mg taken between meals

Probiotic yeast survives antibiotics

Do not take with Nystatin, Diflucan, sporonox or other antifungals. Not expensive


30 Mins before meals 2 caps 3x per day

Tannin based antimycotic, attaches to fungal cells preventing colonisation

Not cheap, casein based


1 or 2 sachets daily

Probiotic, microencapsulated

Very expensive

Undecyclenic acid


450 – 750mg daily in 3 doses

Antifungal 6 times more effective than caprylic acid

Can irritate sensitive GI mucous membranes


Although the terms antifungals and probiotics are often used synonymously their actions are slightly different.


Antifungals work by using the differences between human and fungal cells to kill off the fungal organism without harming our own body cell.   However some antifungals can irritate the gut especially if it is particularly sensitive.

Probiotics work by supplying us with the necessary good bacteria or yeasts our GI tracts need for healthy operation. 

Lactic acid bacteria (LAB) are the most common organisms used.

Homeostatic Soil Organisms HSOs are probiotics comprising organisms that destroy fungus.   HSOs were originally found in soil and subsequently cultivated.


 Excellent, Michelle

This probably answers unasked  questions that brain-fogged people did not even know they had.  This is such an important part of the complete regimen since the abxi will kill off many of the "good gut bugs" that are of great importance to all but especially those of us who labor just to keep a semblance of a real life.   Fortunately, it is very easy for us to just "pop another pill" of acidophilus a couple of hours AFTER our abxi to ensure a numerous number - or eat yogurt  Actually, I just take 1 with my AM supps and another with PM..

Rica        EDSSi 6.7 at beginning - now 2
Ignorance is voluntary bad luck.  Lauritz S.   A true Viking
If you come to a fork in the road, take it. Yogi Berra

3/9 Symptoms returning. Began 5 abxi protocol 5/9 Rifampin 600, Amox 1000, Doxyi 200, MWF Azith 250, flagyli 1000 daily. Began Sept 04 PPMSi EDSSi 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

Michele,  Good work!  Rica's right...this is a vitally helpful addition to the site.  Never heard of some of those things which only demonstrates that the more you know, the more you can imagine how much you still don't know.  This will be a good reference for current and future decision-making.  Thanks,  Joyce~~~MSi caregiver and advocate - Dallas

Joyce~caregiver-advocate in Dallas for Steve J (SPMSi).  CAPi since August 06, Cpni, Mpn, B. burgdorferi, systemic candidiasis, EBVi, CMV & other herpes family viral infectionsi, elevated heavy metals, gluten+casein sensitivity. 

Michele, this is great -- your career pays off for the rest of us. I've heard education described as "putting the cookies (biscuits?) on the lowest shelf;" this is a good example!

Thank you! 


On Stratton protocol for CFSi starting 01/06 (NE Ohio, USA).


On CAPi for CFSi starting 01/06 (NE Ohio, USA)

Began rifampin trial 1/14/09

Currently: on intermittent

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