CPn as a cause of recurrent optic neuritis in a twelve year old boy
Pohl D, Rostasy K, Gieffers J, Maass M, Hanefeld F.
Department of Paediatrics and Paediatric Neurology, Georg August University Gottingen, Germany.
It has been suggested that Chlamydia pneumoniae (C. pneumoniae) is involved in the pathogenesis of diverse diseasesi of the central nervous system (CNSi), including multiple sclerosis. We report the case of a 12-year-old male with isolated recurrent optic neuritis and an associated CNS infection with C. pneumoniae. The patient presented with three attacks of optic neuritis within 5 months. A positive polymerase chain reaction for C. pneumoniae in the cerebrospinal fluid led to the diagnosis of a CNS infection with C. pneumoniae. After treatment with the antibiotic rifampicin, he experienced no further attacks during the follow-up period of 6 years. These findings suggest the possibility of a C. pneumoniae infection as a contributing factor or even causative event for the development of optic neuritis.
Dev Med Child Neurol. 2006 Sep;48(9):770-2.
PMID: 16904026 [PubMed - in process]
I thought this was interesting because optic neuritis is the first symptom of so many people with MSi..........Sarah
Started the Wheldon regime in August 2003, due to very aggressive SPMSi. Moved to intermittent therapy after one year. In May 2006 still take this, two weeks every two months. EDSSi was about 7, now less than 2.
An Itinerary in Light and Shadow Berger.