Clinical Outcomes: a small data-set
Clinical outcomes. Here is a summary of the clinical outcome of treatment on the ten patients seen in my laboratory, with established progressive MSi (or progressive neurological illness with MS-like features.) The diagnosis of MS was made at consultant neurologist level.
10 patients were seen and received treatment and were followed up.
In 7 of these progression of the disease was halted.
In all 7 there was some resolution of symptoms.
In all 7 resolution continues.
6 of these 7 patients had cognitive deficits; these were reversed in all 6.
In 3 of the 10 patients progression continued despite 6M treatment.
In 1 of these patients there was little doubt over compliance with medication.
In 2 of these patients compliance with medication was doubtful.
Acute relapse was seen in no patient.
It is a very small number. It includes only those patients seen and followed up on at least three occasions by myself, so does not include self-reporting or anecdotal cases. (It should be borne in mind that the natural history of progressive disease is towards deterioration: although there may be plateaux of stability, the likelihood of a spontaneous global remission is very slim.) David