Clinical Outcomes: a small data-set

Clinical outcomes. Here is a summary of the clinical outcome of treatment on the ten patients seen in my laboratory, with established progressive MSi (or progressive neurological illness with MS-like features.) The diagnosis of MS was made at consultant neurologist level.

10 patients were seen and received treatment and were followed up.

In 7 of these progression of the disease was halted.
In all 7 there was some resolution of symptoms.
In all 7 resolution continues.
6 of these 7 patients had cognitive deficits; these were reversed in all 6.

In 3 of the 10 patients progression continued despite 6M treatment.
In 1 of these patients there was little doubt over compliance with medication.
In 2 of these patients compliance with medication was doubtful.

Acute relapse was seen in no patient.

It is a very small number. It includes only those patients seen and followed up on at least three occasions by myself, so does not include self-reporting or anecdotal cases. (It should be borne in mind that the natural history of progressive disease is towards deterioration: although there may be plateaux of stability, the likelihood of a spontaneous global remission is very slim.) David

Thank you, David.  The part I like best is "In all 7 the resolution continues".   The part I am sorry about is so little faith, so little compliance.  Personally, I have other things I would rather do, but the trade-off is  -  let me see, should I make a list beginning with thinking, dressing, swallowing, walking..........17 months, every day  and my list continues to grow.


Ignorance is voluntary bad luck.  Lauritz S.   A true Viking

If you come to a fork in the road, take it. Yogi Berra

3/9 Symptoms returning. Began 5 abxi protocol 5/9 Rifampin 600, Amox 1000, Doxyi 200, MWF Azith 250, flagyli 1000 daily. Began Sept 04 PPMSi EDSSi 6.7 Now good days EDSS 1 Mind, like parachute, work only when open. Charlie Chan  In for the duration.&am

Wonderful news, David. Congratulations on the high rate of benefit to your patients.

 David- Thanks for posting this. Really important to have actual data sets available. So many of us "in process" here that it's hard to stand back and know how powerful this work is. These results are unheard of for MSi. Guess this isn't just a pet theory, huh? This goes in the Handbook!

On Wheldon/Stratton protocol for Cpni in CFSi/FMSi since December 2004.


CAPi for Cpni 11/04. Dxi: 25+yrs CFSi & FMSi. Currently: 250 aithromycin mwf, doxycycline 100mg BIDi, restarted Tinii pulses; Vit D2000 units, T4 & T3, 6mg Iodoral

Here is a very interesting and very positive 9-month-long trial for spondyloarthropathy in which chlamydial involvement was suspected. Doxyi alone did very little. The patients in the "real" treatment arm, doxy plus rifampin, saw ~2x reductions in multiple measures - pain (visual analog scale), morning stiffness (hours), tender joint count, swollen joint count.

J Rheumatol 31.10.1973-80, 2004.

I think there are also some negative trials out there for a similar patient population. One would want to examine whether the regimes used in such trials might simply have been far too weak.

Here is the link for the spondyloarthropathy< study.
LDNi since 2-04, Wheldon/Stratton protocol 2006 2009-2011 CCSVI 3 procedures<

More great news - thank-you so much for the report!




On Wheldon protocol for MSi since April, 2006.  LDNi 1994

5oo mgs Ceftin 2 x/day, 500 mgs Zithromax, 500 mgs 2 x tinii pulses,100 mg diflucan, 4.5 ldni; Wheldon protocol for MSi April, 2006 to May 2008. 2008 MRI shows NO NEW DISEASE ACTIVITY, 2012 MRI no new disease activity.

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