Chlamydia Pneumoniae Bacterial Research
Borrelia and Hydroxychloroquine< Not strictly CPn but these cystic bacteria were killed effectively by hydroxychloroquine. Since research into cystic forms is so limited this is included
Repeated respiratory Mycoplasma pneumoniae infections in mice: effects of host genetic background< This paper demonstrates who it is possible a ubiquitous pathogen might cause different diseases in different hosts
Ketoconazole and fluconazole reduce resistance of H pylori to flagyl< Self explanatory important paper.
Induction of immunity in experimental CPn infection< This dissertation holds a good overview of hte lifecycle of CPn as well as offering the possibility of vaccination against this pathogen
Closing on Chlamydia and it's intracellular bag of tricks<This is about chlamydia and it's lifecycle intracellular: how it subverts the host systems and avoids detection
Chlamydia pneumoniae Alters Mildly Oxidized Low-Density Lipoprotein-Induced Cell Death in Human Endothelial Cells, Leading to Necrosis Rather Than Apoptosis<This could also be included in the cardiovascular section as it relates to atherosclerosis, yet it has implications beyond.
Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment< Proof of persistenct in spite of "adequate" therapy
Interesting Curriculum Vitae page with research articles< This researcher is working on vaccine for CPn and mycoplasma. The extensive research links alone make this page valuable. Long and sort of technical with lots of CD4 and t-cell discussion. Photos of intracellular pathogens.
Family Practice article on persistence of CT in women< This article is about CT and how peristence has been shown to be key to recurrent infection with CT.
Persistence in Chlamydiaceae< Technical but readable essay on the current understanding and research related to perisistence of CPn. The concept of persistence is not well understood nor is it generally accepted...YET!
Cpn directly interferes with HIF 1a in host cells< Cpn changes the genesi of the host cell to suit its needs.
Tryptophan depletion as a mechanism of gamma interferon mediated chlamydia persistence< Quote:"Analyses of infected cells cultured in medium with incremental levels of exogenous tryptophan indicated that persistent growth was induced by reducing the amount of this essential amino acid. These studies confirmed that nutrient deprivation by IDO-mediated tryptophan catabolism was the mechanism by which IFN-gamma mediates persistent growth of C. trachomatis."
Role of tryptophan supplementation in chlamydia< This paper is interesting in contrast to the paper above. This author postulates in Medical Hypotheses that giving tryptophan along with antibiotics may force cryptic bodies back into metabolizing states and thus vulnerable to antibiotics.
Silencing or Permanent activation of CPn<Interesting article on these peculiar forms of existence in the body explaining the invisible and chronic nature of CPn.
Persistence<This article relates peristence to atherosclerosis and describes the lack of response by the immune system to the bacterial presence in the cells.